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在“Elsevier电子期刊”中，命中：692条，耗时：0.1119466 秒

在所有数据库中总计命中：937条

1.Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu₅ negative allosteric modulation

作者：Xavier Gó ; mez-Santacana^a ; ^b ; ^c ; ¹ ; James A.R. Dalton^b ; ^d ; Xavier Rovira^e ; ^f ; Jean Philippe Pin^e ; ^f ; Cyril Goudet^e ; ^f ; Pau Gorostiza^c ; ^g ; ^h ; Jesú ; s Giraldo^b ; ^d ; Amadeu Llebaria^a ; ^{amadeu.llebaria@iqac.csic.es}

关键词：mGlu5 ; Isomers ; Partial efficacy ; NAM ; Antagonist ; Inverse agonist

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Binding Modes of Full and Partial Agonists in the Orthosteric Binding Site of the Glycine Receptor

刊名：Biophysical Journal

出版年：2017

3.The effects of varenicline on methamphetamine self-administration and drug-primed reinstatement in male rats

作者：Steven T. Pittenger^a ; ^{pittenges@gmail.com} ; Scott T. Barrett^b ; Shinnyi Chou^c ; Rick A. Bevins^b

关键词：Relapse ; Chantix ; Drug dependence ; Addiction ; Reward enhancement

刊名：Behavioural Brain Research

出版年：2017

4.Characterization of liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in rat partial and full nigral 6-hydroxydopamine lesion models of Parkinson's disease

作者：Henrik H Hansen^a ; ^{hbh@gubra.dk" class="auth_mail" title="E-mail the corresponding author} ; Katrine Fabricius^a ; Pernille Barkholt^a ; Jens D. Mikkelsen^b ; Jacob Jelsing^a ; Charles Pyke^c ; Lotte Bjerre Knudsen^c ; Niels Vrang^a ; ^{niels@gubra.dk" class="auth_mail" title="E-mail the corresponding author}

关键词：Parkinson's disease ; 6-Hydroxydopamine ; Dopaminergic neuron ; Tyrosine hydroxylase ; GLP-1 receptor agonist ; Liraglutide

刊名：Brain Research

出版年：2016

5.Novel full logistic model for estimation of the estrogenic activity of chemical mixtures

作者：Martin Ezechiá ; &scaron ; ^a ; ^b ; Tomá ; &scaron ; Cajthaml^a ; ^b ; ^{cajthaml@biomed.cas.cz" class="auth_mail" title="E-mail the corresponding author}

关键词：Concentration addition ; Estrogen receptor ; Additive effect ; Logistic curve ; Endocrine disrupting compounds ; T47D

刊名：Toxicology

出版年：2016

6.Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives

作者：Elodie Landagaray^a ; ^b ; ¹ ; Mohamed Ettaoussi^a ; ^b ; ¹ ; ² ; ^{m.ettaoussi@yahoo.fr" class="auth_mail" title="E-mail the corresponding author} ; Romain Duroux^a ; ^b ; ^c ; Jean A. Boutin^d ; Daniel-Henri Caignard^e ; Philippe Delagrange^e ; Patricia Melnyk^a ; ^b ; ^c ; Pascal Berthelot^a ; ^b ; ^c ; Saï ; d Yous^a ; ^b ; ^c ; ^{said.yous@univ-lille2.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Melatonin ; MT1 ; MT2 ; Naphthofuranic derivatives ; Partial agonist

刊名：European Journal of Medicinal Chemistry

出版年：2016

7.In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations

作者：Federica Ferrari^a ; Maria Camilla Cerlesi^a ; Davide Malfacini^a ; Laila Asth^b ; Elaine C. Gavioli^b ; Blair V. Journigan^c ; Uma Gayathri Kamakolanu^c ; Michael E. Meyer^c ; Dennis Yasuda^c ; Willma E. Polgar^d ; Anna Rizzi^a ; Remo Guerrini^e ; Chiara Ruzza^a ; Nurulain T. Zaveri^c ; Girolamo Calo^a ; ^{g.calo@unife.it}

关键词：NOP and classical opioid receptors ; Bioluminescence resonance energy transfer ; Calcium mobilization and mouse colon vas deferens and assays ; Receptor and [35S]GTPγS binding

刊名：European Journal of Pharmacology

出版年：2016

8.New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile

作者：Victoria Obermoser^a ; Margarethe E. Urban^b ; Manuela S. Murgueitio^c ; Gerhard Wolber^c ; Ulrich Kintscher^d ; Ronald Gust^a ; ^{ronald.gust@uibk.ac.at" class="auth_mail" title="E-mail the corresponding author}

关键词：PPARγ ; Transactivation ; Cytotoxicity ; Binding mode ; Molecular modeling

刊名：European Journal of Medicinal Chemistry

出版年：2016

9.Terlipressin, a vasoactive prodrug recommended in hepatorenal syndrome, is an agonist of human V1, V2 and V1B receptors: Implications for its safety profile

关键词：Terlipressin ; PubChem CID ; 72081 ; [Arginine8]Vasopressin ; PubChem CID ; 90488786 ; [Lysine8]Vasopressin ; PubChem CID ; 90488785 ; SR49059 ; PubChem CID ; 60943

刊名：Pharmacological Research

出版年：2016

10.The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands

作者：Diana Zurlo^a ; ¹ ; Pamela Ziccardi^a ; ¹ ; Carolina Votino^a ; Tommaso Colangelo^a ; Carmen Cerchia^b ; Fabrizio Dal Piaz^c ; Sabrina Dallavalle^d ; Salvatore Moricca^e ; Ettore Novellino^b ; Antonio Lavecchia^b ; ^{antonio.lavecchia@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Vittorio Colantuoni^a ; Angelo Lupo^a ; ^{lupo@unisannio.it" class="auth_mail" title="E-mail the corresponding author}

关键词：CAD ; caspase-activated deoxyribonuclease ; CRC ; colorectal cancer ; HR-ESI-MS ; high resolution electrospray ionization mass ; LBD ; ligand-binding domain ; MDA ; malondialdehyde ; NCoEx ; nuclear corepressor exchange factor ; PPARs ; peroxisome proliferator-activated receptors ; PBS ; phosphate saline buffer ; PPARγ ; peroxisome proliferator-activated receptor γ ; PPRE ; PPAR response element ; POX/PRODH ; proline oxidase/proline dehydrogenase ; RGZ ; rosiglitazone ; RSV ; Rous Sarcoma Virus ; RXR ; retinoid X receptor

刊名：Biochemical Pharmacology

出版年：2016

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