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在“Elsevier电子期刊”中，命中：356条，耗时：0.1229658 秒

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1.Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor

作者：Zhuang Jin^a ; Hua Lin^a ; Sathish Srinivasan^b ; Jerome C. Nwachukwu^b ; Nelson Bruno^b ; Patrick R. Griffin^a ; Kendall W. Nettles^b ; ; Theodore M. Kamenecka^a ; ^{kameneck@scripps.edu}

关键词：AF-1 ; activation function-1 ; AF-2 ; activation function-2 ; AP-1 ; activator protein 1 ; dppp ; 1 ; 3-bis(diphenylphosphino)propane ; DEX ; dexamethasone ; DIEA ; N ; N-diisopropylethylamine ; FKBP5 ; FK506-binding protein 5 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid-response element ; HATU ; 1-[bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxid hexafluorophosphate ; IL-6 ; Interleukin-6 ; LBD ; ligand-binding domain ; LPS ; lipopolysaccharide ; MMTV ; mouse mammary tumor virus ; NF-κB ; nuclear

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Lessons from tissue compartment-specific analysis of androgen receptor alterations in prostate cancer

作者：Mark Daniel^a ; ^b ; Scott M. Dehm^b ; ^c ; ^d ; ^dehm@umn.edu

关键词：LHRH ; luteinizing hormone releasing hormone ; ADT ; androgen depletion therapy ; CRPC ; castration-resistant prostate cancer ; CYP17 ; cytochrome P450 c17 ; MR ; mineralocorticoid receptor ; ER ; estrogen receptor ; PR ; progestins receptor ; GR ; glucocorticoid receptor ; NTD ; NH2-terminal domain ; AF-1 ; activation function 1 ; LBD ; ligand bind domain ; ARE ; androgen response element ; RIP ; RNA co-immunoprecipitation ; NCOA ; nuclear receptor coactivator ; NCOR ; nuclear receptor corepressor ; CTC ; circulating tumor c

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

3.Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction

作者：Saurabh G. Vispute^a ; Pengli Bu^a ; ^b ; Yuan Le^a ; Xingguo Cheng^a ; ^{chengx@stjohns.edu}

关键词：APAP ; acetaminophen ; bp ; base pair ; ChIP ; chromatin immunoprecipitation ; Cyp ; cytochrome p450 enzyme ; DEX ; dexamethasone ; Fgf21 ; fibroblast growth factor 21 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid receptor response element ; GSH ; Glutathione ; i.p. ; intraperitoneal ; NAPQI ; N-acetyl-p-benzoquinone imine ; PGC1α ; peroxisome proliferator-activated receptor gamma coactivator protein-1α ; PPAR ; peroxisome proliferator-activated receptor ; PXR ; pregnane X receptor ; TSS ; transcription start site

刊名：Toxicology

出版年：2017

4.N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor

作者：Stella Logotheti^a ; ^b ; Nikolas Khoury^a ; Spiros A. Vlahopoulos^c ; Elena Skourti^a ; Dimitra Papaevangeliou^a ; Triantafyllos Liloglou^d ; Vassilis Gorgoulis^e ; Irina Budunova^f ; Anthony M. Kyriakopoulos^g ; Vassilis Zoumpourlis^a ; ^{vzub@eie.gr" class="auth_mail" title="E-mail the corresponding author}

关键词：BrTaur ; N-bromotaurine ; ClTaur ; N-chlorotaurine ; FACS ; fluorescence-activated cell sorting ; GC ; glucocorticoid ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid responsive elements

刊名：Translational Research

出版年：2016

5.Biased signalling from the glucocorticoid receptor: Renewed opportunity for tailoring glucocorticoid activity

作者：Christine R. Keenan ; Michael J. Lew ; Alastair G. Stewart ; ^{astew@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：AP-1 ; activator protein 1 ; AR ; androgen receptor ; cAMP ; cyclic adenosine monophosphate ; p57 ; Kip2 ; cyclin-dependent kinase inhibitor 1C ; COX-2 ; cyclooxygenase-2 ; DC ; deisobutyrylciclesonide ; Dex ; dexamethasone ; KA ; dissociation constant ; ER ; oestrogen receptor ; ERK ; extracellular signal-regulated kinase ; FF ; fluticasone furoate ; GILZ ; glucocorticoid-induced leucine zipper ; GPCR ; G protein coupled receptor ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid response element ; GRIP-1 ; glucocorticoid

刊名：Biochemical Pharmacology

出版年：2016

6.Proliferation and fission of peroxisomes ‿An update

作者：Michael Schrader^a ; ^b ; ^{m.schrader@exeter.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Joseph L. Costello^a ; Luis F. Godinho^b ; Afsoon S. Azadi^a ; Markus Islinger^c

关键词：ER ; endoplasmic reticulum ; GC ; glucocorticoid ; GREs ; glucocorticoid response element ; GR ; glucocorticoid receptor ; mTOR ; mammalian target of rapamycin ; ORE ; oleate response elements ; PBD ; peroxisome biogenesis disorder ; PEX ; peroxin ; PPAR ; peroxisome proliferator-activated receptor ; PPRE ; peroxisome proliferator response element ; PTS ; peroxisomal targeting signal ; ROS ; reactive oxygen species

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

7.Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants

作者：Diana A. Stavreva^a ; ^{stavrevd@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Lyuba Varticovski^a ; Ludmila Levkova^b ; Anuja A. George^a ; ¹ ; Luke Davis^a ; ² ; Gianluca Pegoraro^a ; Vicki Blazer^c ; Luke Iwanowicz^c ; Gordon L. Hager^a ; ^{hagerg@exchange.nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：EDCs ; endocrine disrupting chemicals ; TH ; thyroid hormone ; GR ; glucocorticoid receptor ; TR ; thyroid receptor ; T3 ; 3 ; 3&prime ; 5-triiodothyronine ; TRIAC ; Tiratricol or triiodothyroacetic acid ; rT3 ; reverse triiodothyronine or 3 ; 3&prime ; 5&prime ; -triiodothyronine ; T4 ; thyroxine ; BPA ; Bisphenol A ; TBBPA ; 3 ; 3&prime5 ; 5&prime ; -tetrabromobisphenol A ; TREs ; TH-response elements ; RXR ; retinoid X receptor ; NCoR ; nuclear corepressor ; SMRT ; silencing mediator of retinoid and thyroid hormone receptor ; HDAC

刊名：Toxicology

出版年：2016

8.Voluntary exercise blocks Western diet-induced gene expression of the chemokines CXCL10 and CCL2 in the prefrontal cortex

作者：Jesse L. Carlin^a ; Nicola Grissom^b ; Zhe Ying^c ; Fernando Gomez-Pinilla^c ; Teresa M. Reyes^b ; ^{reyesta@ucmail.uc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CREB ; cAMP response element binding protein ; CNS ; central nervous system ; CCL2 ; chemokine (C-C Motif) ligand 2 ; CCR2 ; chemokine (C-C Motif) receptor 2 ; CTRL ; control ; CXCL10 ; C-X-C motif chemokine 10 ; COX-2 ; cyclooxygenase 2 ; EPM ; elevated plus maze ; EX RD ; exercise-regular diet group ; EX-WD ; exercise-western diet group ; GFAP ; glial fibrillary acidic protein ; GR ; glucocorticoid receptor ; HFD ; high fat diet ; IL-1β ; interleukin 1 beta ; IL-1 ; interleukin-1 ; IL-18 ; interleukin-18 ; IL-6 ; interleukin-

刊名：Brain, Behavior, and Immunity

出版年：2016

9.Mechanisms and risk assessment of steroid resistance in acute kidney transplant rejection

作者：Niels V. Rekers^a ; ^b ; J.W. de Fijter^c ; Frans H.J. Claas^a ; Michael Eikmans^a ; ^{m.eikmans@lumc.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：AP-1 ; activator protein-1 ; AR ; acute rejection ; ATG ; anti-thymocyte globulin ; CAN ; chronic allograft nephropathy ; CBP ; CREB-binding protein ; CREB ; cyclic AMP-responsive element-binding ; DBD ; DNA-binding domain ; F2R ; coagulation factor II receptor ; FKBP ; FK506-binding protein ; GC ; glucocorticoid ; GCs ; glucocorticoids ; GR ; glucocorticoid receptor ; GRα ; glucocorticoid receptor α ; GRβ ; glucocorticoid receptor β ; GRE ; glucocorticoid responsive element ; GRP-1 ; GR-interacting protein 1 ; HDAC ; histone d

刊名：Transplant Immunology

出版年：2016

10.Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent

作者：Sayantani Sinha ; ^{Sinhas@email.chop.edu" class="auth_mail" title="E-mail the corresponding author} ; Kenta Uchibe ; Yu Usami ; Maurizio Pacifici ; Masahiro Iwamoto ; ^{IwamotoM@email.chop.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：HO ; heterotopic ossification ; FOP ; Fibrodysplasia Ossificans Progressiva ; RAR ; retinoic acid receptor ; BMP ; bone morphogenetic protein ; GRE ; glucocorticoid response element ; RARE ; retinoic acid response element ; ACVR1 ; activin receptor 1 ; ALK2 ; activin receptor-like kinase-2 ; NSAIDs ; non-steroidal anti-inflammatory drugs

刊名：Bone

出版年：2016

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