作者：Ana Salomé ; Pires^a ; ^b ; ^c ; ^d ; ¹ ; ^{a.salome.pires@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Clá ; udia Raquel Marques^a ; ¹ ; ^{claudiarfmarques@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Joã ; o Carlos Encarnaç ; ã ; o^a ; ^b ; ^{joaocrispim90@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ana Margarida Abrantes^a ; ^b ; ^c ; ^{mabrantes@fmed.uc.pt" class="auth_mail" title="E-mail the corresponding author} ; Ana Catarina Mamede^a ; ^b ; ^c ; ^e ; ^{ana_mamede@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Mafalda Laranjo^a ; ^b ; ^c ; ^{mafaldalaranjo@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ana Cristina Gonç ; alves^a ; ^b ; ^f ; ^{acc.goncalves@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ana Bela Sarmento-Ribeiro^a ; ^b ; ^f ; ^g ; ^{absarmento@fmed.uc.pt" class="auth_mail" title="E-mail the corresponding author} ; Maria Filomena Botelho^a ; ^b ; ^c ; ^{mfbotelho@fmed.uc.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：AA ; ascorbic acid ; CRC ; colorectal cancer ; DHA ; dehydroascorbic acid ; GLUT ; glucose transporters ; HIF ; hypoxia inducible factor ; IC50 ; half-maximal inhibitory concentration ; ROS ; reactive oxygen species ; SOD ; superoxide dismutase ; SVCT ; sodium-dependent vitamin C transporter ; ψm ; mitochondrial membrane potential

刊名：European Journal of Cell Biology

出版年：2016

作者：Poonsit Hiransai¹ ; ² ; ^{poonsit.hi@wu.ac.th" class="auth_mail" title="E-mail the corresponding author} ; ^{poonsit.hi@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jitbanjong Tangpong² ; ³ ; Chuthamat Kumbuar² ; Namon Hoonheang² ; Onrunee Rodpech² ; Padchara Sangsuk² ; Urairat Kajklangdon² ; Waraphorn Inkaow²

关键词：Tithonia diversifolia ; Anti-nitric oxide production ; Anti-proliferation ; Antioxidant

刊名：Asian Pacific Journal of Tropical Biomedicine

出版年：2016

作者：Jun Yeon Park¹ ; ^☆ ; Pilju Choi² ; ^☆ ; Ho-kyong Kim³ ; Ki Sung Kang¹ ; ^{kkang@gachon.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Jungyeob Ham² ; ^{ham0606@kist.re.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：anticancer ; ginsenoside ; microwave ; Panax ginseng ; prostate cancer

刊名：Journal of Ginseng Research

出版年：2016

作者：Jeanny Kwon ; MD ; PhD^&lowast ; ; Dan Hyo Kim ; MS^&dagger ; ; Ji Min Park ; BS^&dagger ; ; Young Hee Park ; MD^&lowast ; ; Yeo Hyun Hwang ; PhD^&dagger ; ; Hong-Gyun Wu ; MD ; PhD^&lowast ; ; ^&Dagger ; ; Kyung Hwan Shin ; MD ; PhD^&lowast ; ; In Ah Kim ; MD ; PhD^&lowast ; ; ^&dagger ; ; ^&Dagger ; ; ^§ ; ; ^{inah228@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author}

刊名：International Journal of Radiation Oncology*Biology*Physics

出版年：2016

作者：Elena Diez-Cecilia^a ; Robert Carson^b ; Brendan Kelly^a ; Sandra van Schaeybroeck^b ; James T. Murray^c ; Isabel Rozas^a ; ^{rozasi@tcd.ie" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; colorectal cancer ; PK ; protein kinase ; PKI ; protein kinase inhibitor ; FDA ; Federal Drug Agency ; HL-60 ; acute myeloid leukaemia cell line ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; IC50 ; half maximal inhibitory concentration ; RCSB Protein Data Bank ; Research Collaboratory for Structural Bioinformatics protein data bank ; MD ; molecular dynamics ; 4-Cl-3-CF3-Ph ; 4-chloro-3-trifluoromethylphenyl ; DFG-motif ; aspartic acid ; phenylalanine ; glycine motif ; FRET ; fluorescence r

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

作者：Paul Martin ; PhD¹ ; ^{paul.martin@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Michael Gillen ; BS (Pharm)² ; David Millson ; MD¹ ; ^* ; Stuart Oliver ; MD¹ ; Clive Brealey ; PhD¹ ; ^* ; Robert Elsby ; PhD¹ ; ^* ; Muhammad Baluom ; PhD³ ; David Lau ; PhD³ ; Tim Mant ; MB⁴

关键词：digoxin ; drug interaction ; fostamatinib ; pharmacokinetic parameters ; rheumatoid arthritis

刊名：Clinical Therapeutics

出版年：2015

作者：Katharina Korpis ; Frauke Weber ; Stefanie Brune ; Bernhard W眉nsch ; Patrick J. Bednarski

关键词：AI ; apoptosis inhibitor ; Bmax ; maximal ligand binding sites ; BODIPY 665/676 C11 ; 4-difluoro-3 ; 5-bis(4-phenyl-1 ; 3-butadienyl)-4-bora-3a ; 4a-diaza-s-indacene ; DCFDA ; 2&prime ; 7&prime ; -dichlorofluorescein diacetate ; DAPI ; 4 ; 6-diamino-2-phenylindole ; DMSO ; dimethylsulfoxide ; DTG ; ditolylguanidine ; IC50 ; half maximal inhibitory drug concentration ; Kd ; ligand dissociation constant ; Ki ; inhibitory dissociation constant ; LC3B ; microtubule-associated protein light chain 3 ; LPO ; Lipid peroxidation ; 3-MA ; 3

刊名：Bioorganic and Medicinal Chemistry

出版年：1 January, 2014

作者：Natalia Lisiak ; Anna Paszel-Jaworska ; Barbara Bednarczyk-Cwynar ; Lucjusz Zaprutko ; Mariusz Kaczmarek ; Maria Rybczy艅ska

关键词：BECN 1 ; beclin 1 ; CDDO ; 2-cyano-3 ; 12-dioxoolean-1 ; 9-dien-28-oic acid ; IC50 ; half maximal inhibitory concentration ; HIMOXOL ; methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate ; MAPK ; mitogen-activated protein kinase ; MAP LC3尾 ; microtubule-associated protein light chain beta ; MDC ; monodansylcadaverine ; OA ; oleanolic acid ; UA ; ursolic acid

刊名：Chemico-Biological Interactions

出版年：5 February, 2014

作者：Brian R. Vuillemenot^a ; ^{bvuillemenot@bmrn.com" class="auth_mail} ; Derek Kennedy^a ; Randall P. Reed^b ; Robert B. Boyd^b ; Mark T. Butt^c ; Donald G. Musson^a ; Steve Keve^a ; Rhea Cahayag^a ; Laurie S. Tsuruda^a ; Charles A. O'Neill^a

关键词：aCSF ; artificial cerebrospinal fluid ; AUC ; area under the curve ; CHO ; Chinese hamster ovary ; CLN2 ; ceroid lipofuscinosis neuronal type 2 ; Cmax ; maximal concentration ; CRIM ; cross-reactive immunological material ; D ; deep tissue ; ERT ; enzyme replacement therapy ; EU ; endotoxin unit ; H&E ; hematoxylin and eosin ; GFAP ; glial fibrillary acidic protein ; ICV ; intracerebroventricular ; IT ; intrathecal ; IT-L ; intrathecal-lumbar ; LLOQ ; lower limit of quantification ; NBF ; neutral buffered formalin ; ND ; not de

刊名：Toxicology and Applied Pharmacology

出版年：15 May, 2014

作者：L铆gia C. Gomes-da-Silva ; Jos茅 S. Ramalho ; Maria C. Pedroso de Lima ; S茅rgio Sim玫es ; Jo茫o N. Moreira

关键词：PLK1 ; polo-like kinase 1 ; siRNA ; small-interfering RNA ; CTR ; control ; PC3 ; PC3 prostate cancer cells ; HMEC-1 ; human microvascular endothelial cells ; eGFP ; enhanced Green Fluorescent Protein ; IC50 ; half maximal death concentration ; DRI ; dose reduction index ; G2/M phases ; G2/mitosis phases ; DOTAP ; 1 ; 2-dioleoyl-3-trimethylammonium-propane ; DSPC ; 1 ; 2-distearoyl-sn-glycero-3-phosphocholine ; DOPE ; 1 ; 2-dioleoyl-sn-glycero-3-phosphoethanolamine ; C16-Ceramide mPEG2000 ; N-Palmitoyl-Sphingosine-1-[Succiny

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：November, 2013