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在“Elsevier电子期刊”中，命中：135条，耗时：0.0759687 秒

在所有数据库中总计命中：193条

1.NS5A resistance leading to failure of 24-week therapy with sofosbuvir/ledipasvir and ribavirin for the treatment of hepatitis C genotype 1a infection in a HIV-1 co-infected patient

作者：Ksenia Sevastianova^a ; ^{ksenia.sevastianova@helsinki.fi" class="auth_mail" title="E-mail the corresponding author} ; Jonathan Dean^b ; Ciaran Bannan^a ; Miriam Coghlan^a ; Gillian Farrell^a ; Catherine Murray^a ; Cillian F. De Gascun^b ; Colm Bergin^a ; ^c

关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; cART ; combination antiretroviral therapy ; DAA ; direct-acting antiviral ; DDI ; drug&ndash ; drug interaction ; EOTR ; end-of-treatment response ; GT ; genotype ; HCV ; hepatitis C virus ; HIV-1 ; human immunodeficiency virus type 1 ; IFN ; interferon ; INR ; international normalized ratio ; LDV ; ledipasvir ; MELD ; Model for End-Stage Liver Disease ; NS3 ; non-structural protein 3 ; NS5A ; non-structural protein 5A ; NS5B ; non-structural protein 5B ; PI ; pr

刊名：Journal of Clinical Virology

出版年：2016

2.The importance of resistance to direct antiviral drugs in HCV infection in clinical practice

作者：Christoph Sarrazin ; ^{sarrazin@em.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV ; hepatitis C virus ; DAA ; direct-acting antiviral agent ; NS3 ; non-structural protein 3 ; NS5A ; non-structural protein 5A ; NS5B ; non-structural protein 5B ; RAVs ; resistance associated variants ; IP-10 ; interferon-gamma-inducible protein 10 ; IFNL4 ; interferon lambda 4 ; IL28B ; interleukin 28B ; HIV ; human immunodeficiency virus ; HBV ; hepatitis B virus ; PEG/R ; pegylated interferon plus ribavirin ; PI ; protease inhibitor ; SVR ; sustained virological response ; EC50 ; half maximal effective concentration

刊名：Journal of Hepatology

出版年：2016

3.Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B

关键词：CYP4F12 ; Hepatitis C virus ; Viral replication

刊名：Biochemical and Biophysical Research Communications

出版年：2016

4.The cyclophilin-inhibitor alisporivir stimulates antigen presentation thereby promoting antigen-specific CD8⁺ T cell activation

作者：Katharina Esser-Nobis¹ ; Julia Schmidt² ; Katja Nitschke² ; Christoph Neumann-Haefelin² ; Robert Thimme² ; Volker Lohmann¹ ; ^{Volker_lohmann@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV ; hepatitis C virus ; CsA ; cyclosporine A ; MHC ; major histocompatibility complex ; Cyp ; cyclophilin ; E ; T ratio ; effector-to-target ratio ; NS5BEM ; epitope-matched HCV non-structural protein 5B ; IFN ; interferon ; b2m ; beta-2 microglobulin ; GLuc ; Gaussia-luciferase ; TFR ; transferrin receptor ; ERAP1 ; endoplasmic reticulum aminopeptidase 1 ; SFA ; sanglifehrin A ; CsH ; cyclosporine H ; TCR ; T cell receptor ; GeoMFI ; geometric mean fluorescence intensity

刊名：Journal of Hepatology

出版年：2016

5.The -94Ins/DelATTG polymorphism in NFκB1 promoter modulates chronic hepatitis C and liver disease progression

作者：Fatima-Zohra Fakhir^a ; ^b ; Mustapha Lkhider^c ; Wafaa Badre^d ; Rhimou Alaoui^d ; Pascal Pineau^e ; Sayeh Ezzikouri^a ; ^{sayeh.ezzikouri@pasteur.ma" class="auth_mail" title="E-mail the corresponding author} ; Soumaya Benjelloun^a ; ^{soumaya.benjelloun@pasteur.ma" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV ; Hepatitis C Virus ; PRR ; pattern recognition receptor ; NF-κB ; nuclear factor-kappa B ; TNFR1 ; tumor necrosis factor receptor 1 ; NS5B ; non-structural protein 5B ; IκB ; inhibitor of kappa B ; TNFA ; tumor necrosis factor alpha ; IL8 ; interleukin 8 ; IL1B ; interleukin 1B

刊名：Infection, Genetics and Evolution

出版年：2016

6.Direct anti-HCV agents

作者：Xingquan Zhang ^{xiz002@ucsd.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C virus ; Cure HCV ; Sustained virologic response ; Direct antiviral agents ; NS3/4A protease inhibitor

刊名：Acta Pharmaceutica Sinica B

出版年：2016

7.Synthesis of novel imidazo[1,2-a]pyridine-4-hydroxy-2H-coumarins by Groebke-Blackburn-Bienaymé multicomponent reaction as potential NS5B inhibitors

作者：Parth Manvar ; Faraz Shaikh ; Rajesh Kakadiya ; ^{r.kakadiya.82@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Krunal Mehariya ; Ranjan Khunt ; Bipin Pandey ; Anamik Shah ; ^{anamik_shah@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Groebke&ndash ; Blackburn&ndash ; Bienaym&eacute ; reaction ; Hepatitis C virus ; 4-Hydroxy-3-Formylcoumarin ; Imidazo[1 ; 2-a]pyridine ; NS5B inhibitors ; Molecular docking ; Multicomponent reaction (MCR)

刊名：Tetrahedron

出版年：2016

8.Inhibition of hepatitis C virus in mouse models by lipidoid nanoparticle-mediated systemic delivery of siRNA against PRK2

作者：Jae-Su Moon ; BS^a ; ¹ ; Seung-Hoon Lee ; BS^a ; ¹ ; Song-Hee Han ; MS^a ; Eun-Jung Kim ; MS^a ; Hee Cho ; BS^a ; Wooseong Lee ; BS^a ; Mi-Kyung Kim ; PhD^a ; Tae-Eun Kim ; MS^a ; Hyun-Ji Park ; BS^a ; Jin-Kyu Rhee ; PhD^b ; ² ; Seong-Jun Kim ; PhD^a ; ³ ; Seung-Woo Cho ; PhD^a ; Seung Hyun Han ; PhD^c ; Jong-Won Oh ; PhD^a ; ^{jwoh@yonsei.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV ; siRNA ; Lipidoid ; Nanoparticles ; PRK2 ; Antivirals

刊名：Nanomedicine: Nanotechnology, Biology and Medicine

出版年：2016

9.Therapeutic potential of Taraxacum officinale against HCV NS5B polymerase: In-vitro and In silico study

作者：Sidra Rehman^a ; ^{sidrarehman@ciit.net.pk" class="auth_mail" title="E-mail the corresponding author} ; ^{sidra.cemb@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Bushra Ijaz^b ; Nighat Fatima^c ; Syed Aun Muhammad^d ; Sheikh Riazuddin^e

关键词：HCV ; Hepatitis C virus ; TM ; Taraxacum Officinale ; MOE ; Molecular operator Environment ; Huh-7 ; Human Hepatoma cell line ; CHO ; Chinese Hamster Ovarian cells

刊名：Biomedicine & Pharmacotherapy

出版年：2016

10.Synthesis and anti-HCV determinant motif identification in pyranone carboxamide scaffold

作者：Tuniki Balaraju^a ; Ananda Kumar Konreddy^a ; Afsana Parveen^a ; Massaki Toyama^b ; Wataru Ito^b ; Srinivas Karampuri^a ; Masanori Baba^b ; Ashoke Sharon^a ; ^{asharon@bitmesra.ac.in" class="auth_mail" title="E-mail the corresponding author} ; Chandralata Bal^a ; ^{cbal@bitmesra.ac.in" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C Virus ; Pyranone carboxamide ; Non-nucleoside inhibitor

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

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