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在“Elsevier电子期刊”中，命中：59条，耗时：0.0139939 秒

在所有数据库中总计命中：80条

1.Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative

作者：Kiyoshi Takasuna^a ; ^b ; ^c ; ^{takasuna.kiyoshi.a3@daiichisankyo.co.jp} ; Keiichi Asakura^b ; ^c ; ^d ; Seiichi Araki^b ; ^c ; ^e ; Hiroyuki Ando^b ; ^c ; ^f ; Katsuyuki Kazusa^b ; ^c ; ^g ; Takashi Kitaguchi^b ; ^c ; ^h ; Takeshi Kunimatsu^b ; ^c ; ⁱ ; Shinobu Suzuki^b ; ^c ; ^j ; Norimasa Miyamoto^b ; ^c ; ^k

关键词：CSAHi ; Consortium for Safety Assessment using Human iPS Cells ; FPDc10 ; concentration inducing FPDc prolongation by 10% ; CMIS ; cell motion imaging system ; hiPS-CMs ; human induced pluripotent stem cell-derived cardiomyocytes ; CRD ; contraction-relaxation duration ; IBD10 ; impedance-based duration from 10% rising to 10% falling amplitude ; PWD90 ; peak width duration at 90% amplitude ; MEA ; multi-electrode array ; CPMP ; committee for proprietary medicinal products ; APD ; action potential duration ; TdP ; To

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2017

2.Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

作者：Gun-Sik Cho¹ ; ² ; ⁸ ; Dong I. Lee¹ ; ⁸ ; Emmanouil Tampakakis¹ ; ² ; Sean Murphy¹ ; ² ; Peter Andersen¹ ; ² ; Hideki Uosaki¹ ; ² ; ⁹ ; Stephen Chelko¹ ; Khalid Chakir¹ ; Ingie Hong³ ; Kinya Seo¹ ; Huei-Sheng Vincent Chen⁴ ; Xiongwen Chen⁵ ; Cristina Basso⁶ ; ⁷ ; Steven R. Houser⁵ ; Gordon F. Tomaselli¹ ; Brian O&rsquo ; Rourke¹ ; Daniel P. Judge¹ ; David A. Kass¹ ; ^{dkass@jhmi.edu} ; Chulan Kwon¹ ; ² ; ¹⁰ ; ^{ckwon13@jhmi.edu}

关键词：cardiomyocyte ; maturation ; iPS ; cardiac progenitor ; neonatal ; disease modeling ; cardiomyopathy ; ARVC ; T-tubule ; calcium transient ; sarcomere shortening

刊名：Cell Reports

出版年：2017

3.Evaluation of nefazodone-induced cardiotoxicity in human induced pluripotent stem cell-derived cardiomyocytes

作者：Sujeong Lee^a ; ¹ ; ^{crystalee@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Hyang-Ae Lee^a ; ^b ; ^c ; ¹ ; ^{hyangaelee@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Sung Woo Choi^b ; ^{djmaya@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Sung Joon Kim^b ; ² ; ^{sjoonkim@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Ki-Suk Kim^a ; ^c ; ² ; ^{idkks00@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) ; Cardiotoxicity ; Nefazodone ; Patch clamp ; Action potentials ; Ion channels

刊名：Toxicology and Applied Pharmacology

出版年：2016

4.CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability-

作者：Yumiko Nozaki^a ; Yayoi Honda^a ; Hitoshi Watanabe^a ; Shota Saiki^b ; ^g ; ¹ ; Kiyotaka Koyabu^b ; Tetsuji Itoh^b ; Chiho Nagasawa^c ; ^g ; ¹ ; Chiaki Nakamori^c ; Chiaki Nakayama^c ; Hiroshi Iwasaki^c ; Shinobu Suzuki^d ; ^g ; ¹ ; Ikumi Washio^d ; Etsushi Takahashi^e ; ^g ; ¹ ; Kaori Miyamoto^e ; Atsuhiro Yamanishi^f ; ^g ; ¹ ; Hiroko Endo^f ; Junko Shinozaki^f ; Hisashi Nogawa^f ; Takeshi Kunimatsu^a ; ^g ; ^h ; ¹ ; ^{takeshi-kunimatsu@ds-pharma.co.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Consortium for drug safety assessment using human iPS cells (CSAHi) ; Comprehensive in vitro Proarrthythmia assay (CiPA) ; Inter-facility variability ; Multi electrode array (MEA) ; Human iPS cells-derived cardiomyocytes (hiPS-CMs) ; Early after depolarization (EAD) or triggered activity (TA)

刊名：Regulatory Toxicology and Pharmacology

出版年：2016

5.Automated detection and analysis of depolarization events in human cardiomyocytes using MaDEC

作者：Agnieszka F. Szymanska^a ; ^{aggie.szymanska@gmail.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; Christopher Heylman^bAuthor Vitae ; Rupsa Datta^bAuthor Vitae ; Enrico Gratton^bAuthor Vitae ; Zoran Nenadic^aAuthor Vitae

关键词：Voltage-sensitive dye imaging ; hiPS derived cardiomyocytes ; Signal detection ; Matched filter ; Classification

刊名：Computers in Biology and Medicine

出版年：2016

6.Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging

作者：Graham T. Dempsey^a ; Khuram W. Chaudhary^b ; ^{khuram.w.chaudhary@gsk.com" class="auth_mail" title="E-mail the corresponding author} ; Nicholas Atwater^a ; Cuong Nguyen^a ; Barry S. Brown^b ; John D. McNeish^c ; Adam E. Cohen^d ; ^e ; ^f ; Joel M. Kralj^a

关键词：CiPA ; Comprehensive in vitro Proarrhythmia Assay ; TdP ; Torsades de Pointes ; AP ; action potential ; CT ; Ca2 ; + transient ; hiPSC ; human induced pluripotent stem cell ; CM ; cardiomyocyte ; CaViar ; Ca2 ; + and voltage indicator ; CheRiff ; channelrhodopsin variant ; EAD ; early after depolarization ; ECG ; electrocardiogram ; hERG ; human Ether-à ; -go-go-Related Gene ; MEA ; multi-electrode array ; Arch ; Archaerhodopsin ; VSD ; voltage sensitive dye

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

7.Characterization of the physiology and cardiotoxicity of cardiac 3D microtissues of hiPSC-derived cardiomyocytes (hiPSC-CMs)

作者：Maria P. Hortigon-Vinagre^a ; ; Victor Zamora^a ; ^b ; Viben Alageswaran^a ; David Craig^a ; David Fluri^c ; Francis L. Bruton^a ; ^b ; Irina Agarkova^c ; Jens M. Kelm^c ; Margaret A. Craig^b ; Godfrey L. Smith^a ; ^b

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

8.A comparison of drug-induced changes in electrical excitability using optogenetic sensors and conventional field stimulation in hiPS-derived cardiomyocytes (hiPSC-CMs)

作者：Victor Zamora^a ; ^b ; ; Maria Hortigon-Vinagre^a ; ^b ; Andrew Allan^a ; Hua Rong Lu^c ; Francis Burton^a ; ^b ; David Gallacher^c ; Godfrey Smith^a ; ^b

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

9.Electrophysiological characterization of iCell² hiPSC derived cardiomyocytes: The new generation of CDI hiPSC-CMs

作者：Amy E. Taylor^a ; ; Victor Zamora^a ; ^b ; Maria P. Hortigon-Vinagre^a ; ^b ; Andrew Allan^a ; Francis L. Burton^a ; ^b ; Blake D. Anson^c ; Margaret A. Craig^a ; Godfrey L. Smith^a ; ^b

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

10.Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes

作者：Haoyu Zeng ; ^{haoyu.zeng@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Maria I. Roman ; Edward Lis ; Armando Lagrutta ; Frederick Sannajust

关键词：hiPSC-CM ; Preclinical cardiac safety ; Ca2 ; +-transient

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

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