搜索页_+hiPSC-CMs

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Wiley电子期刊(3)	NATURE电子期刊(1)	ACS电子期刊(3)
SpringerLink电子期刊(12)	Elsevier电子期刊(31)

在“Elsevier电子期刊”中，命中：31条，耗时：0.0119943 秒

在所有数据库中总计命中：50条

1.Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

作者：Gun-Sik Cho¹ ; ² ; ⁸ ; Dong I. Lee¹ ; ⁸ ; Emmanouil Tampakakis¹ ; ² ; Sean Murphy¹ ; ² ; Peter Andersen¹ ; ² ; Hideki Uosaki¹ ; ² ; ⁹ ; Stephen Chelko¹ ; Khalid Chakir¹ ; Ingie Hong³ ; Kinya Seo¹ ; Huei-Sheng Vincent Chen⁴ ; Xiongwen Chen⁵ ; Cristina Basso⁶ ; ⁷ ; Steven R. Houser⁵ ; Gordon F. Tomaselli¹ ; Brian O&rsquo ; Rourke¹ ; Daniel P. Judge¹ ; David A. Kass¹ ; ^{dkass@jhmi.edu} ; Chulan Kwon¹ ; ² ; ¹⁰ ; ^{ckwon13@jhmi.edu}

关键词：cardiomyocyte ; maturation ; iPS ; cardiac progenitor ; neonatal ; disease modeling ; cardiomyopathy ; ARVC ; T-tubule ; calcium transient ; sarcomere shortening

刊名：Cell Reports

出版年：2017

2.Evaluation of nefazodone-induced cardiotoxicity in human induced pluripotent stem cell-derived cardiomyocytes

作者：Sujeong Lee^a ; ¹ ; ^{crystalee@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Hyang-Ae Lee^a ; ^b ; ^c ; ¹ ; ^{hyangaelee@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Sung Woo Choi^b ; ^{djmaya@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Sung Joon Kim^b ; ² ; ^{sjoonkim@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Ki-Suk Kim^a ; ^c ; ² ; ^{idkks00@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) ; Cardiotoxicity ; Nefazodone ; Patch clamp ; Action potentials ; Ion channels

刊名：Toxicology and Applied Pharmacology

出版年：2016

3.Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging

作者：Graham T. Dempsey^a ; Khuram W. Chaudhary^b ; ^{khuram.w.chaudhary@gsk.com" class="auth_mail" title="E-mail the corresponding author} ; Nicholas Atwater^a ; Cuong Nguyen^a ; Barry S. Brown^b ; John D. McNeish^c ; Adam E. Cohen^d ; ^e ; ^f ; Joel M. Kralj^a

关键词：CiPA ; Comprehensive in vitro Proarrhythmia Assay ; TdP ; Torsades de Pointes ; AP ; action potential ; CT ; Ca2 ; + transient ; hiPSC ; human induced pluripotent stem cell ; CM ; cardiomyocyte ; CaViar ; Ca2 ; + and voltage indicator ; CheRiff ; channelrhodopsin variant ; EAD ; early after depolarization ; ECG ; electrocardiogram ; hERG ; human Ether-à ; -go-go-Related Gene ; MEA ; multi-electrode array ; Arch ; Archaerhodopsin ; VSD ; voltage sensitive dye

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

4.Electrophysiological characterization of iCell² hiPSC derived cardiomyocytes: The new generation of CDI hiPSC-CMs

作者：Amy E. Taylor^a ; ; Victor Zamora^a ; ^b ; Maria P. Hortigon-Vinagre^a ; ^b ; Andrew Allan^a ; Francis L. Burton^a ; ^b ; Blake D. Anson^c ; Margaret A. Craig^a ; Godfrey L. Smith^a ; ^b

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

5.Characterization of the physiology and cardiotoxicity of cardiac 3D microtissues of hiPSC-derived cardiomyocytes (hiPSC-CMs)

作者：Maria P. Hortigon-Vinagre^a ; ; Victor Zamora^a ; ^b ; Viben Alageswaran^a ; David Craig^a ; David Fluri^c ; Francis L. Bruton^a ; ^b ; Irina Agarkova^c ; Jens M. Kelm^c ; Margaret A. Craig^b ; Godfrey L. Smith^a ; ^b

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

6.Use of FDSS/μCell imaging platform for preclinical cardiac electrophysiology safety screening of compounds in human induced pluripotent stem cell-derived cardiomyocytes

作者：Haoyu Zeng ; ^{haoyu.zeng@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Maria I. Roman ; Edward Lis ; Armando Lagrutta ; Frederick Sannajust

关键词：hiPSC-CM ; Preclinical cardiac safety ; Ca2 ; +-transient

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

7.Interaction between amiodarone and hepatitis-C virus nucleotide inhibitors in human induced pluripotent stem cell-derived cardiomyocytes and HEK-293 Cav_1.2 over-expressing cells

作者：Armando Lagrutta ; PhD ; ^{armando_lagrutta@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Haoyu Zeng ; PhD ; John Imredy ; PhD ; Bharathi Balasubramanian ; MS ; Spencer Dech ; MA ; Edward Lis ; BS ; Jixin Wang ; MS ; Jin Zhai ; MS ; Joseph DeGeorge ; PhD ; Frederick Sannajust ; PharmD ; PhD

关键词：AMIO ; amiodarone ; CCBs ; calcium channel blockers ; DEA ; desethylamiodarone ; DDI ; drug-drug interaction(s) ; DRON ; dronedarone ; FP ; field potential ; HCV-NI ; hepatitis-C virus nucleotide inhibitor ; hiPSC-CMs ; human induced Pluripotent Stem Cell-derived Cardiomyocytes ; IMP ; impedance ; MNI-1 ; Merck-Nucleotide Inhibitor #1 ; NCX1 ; sodium-calcium exchanger 1 ; P-gp ; P-glycoprotein ; SERCA ; sarcoplasmic-endoplasmic reticulum calcium-ATPase ; SOF ; sofosbuvir

刊名：Toxicology and Applied Pharmacology

出版年：2016

8.Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation

作者：Icilio Cavero^a ; ^{iciliocavero@outlook.com" class="auth_mail" title="E-mail the corresponding author} ; Jean-Michel Guillon^b ; Veronique Ballet^b ; Mike Clements^c ; Jean-Fré ; dé ; ric Gerbeau^d ; Henry Holzgrefe^e

关键词：Comprehensive in vitro Proarrhythmia Assay (CiPA) ; Field potential data sampling and analysis ; Induced pluripotent cell cardiomyocytes (hiPSC-CMs) ; Multi electrode array (MEA) ; Patch clamp technologies ; Pending issues and solutions ; Validation ; Voltage sensitive dye (VSD)

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

9.Safety pharmacology studies using EFP and impedance

作者：Alison Obergrussberger ; ^{ali@nanion.de" class="auth_mail" title="E-mail the corresponding author} ; Krisztina Juhasz ; Ulrich Thomas ; Sonja Stö ; lzle-Feix ; Nadine Becker ; Leo Dö ; rr ; Matthias Beckler ; Corina Bot ; Michael George ; Niels Fertig

关键词：CardioExcyte 96 ; Dofetilide ; E4031 ; EAD-like ; Extracellular field potential ; Impedance ; Isoproterenol ; Nifedipine ; Pentamidine ; Safety pharmacology

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

10.The prospective IQ-CSRC trial: A prototype early clinical proarrhythmia assessment investigation for replacing the ICH E14 thorough QTc (TQT) study

作者：Icilio Cavero^a ; ^{iciliocavero@outlook.com" class="auth_mail" title="E-mail the corresponding author} ; Henry Holzgrefe^b ; Mike Clements^c

关键词：AP ; cardiac action potential ; CiPA ; comprehensive in vitro proarrhythmia assay ; CSRC ; Cardiac Safety Research Consortium ; Cmax ; maximal plasma concentration ; CTWG ; clinical translational working group ; DRest ; rate-normalized Tpeak ; &minus ; ; Tend ; = ; Tpe interval ; ECG ; electrocardiogram ; E-R ; exposure-response ; FDA ; Food and Drug Administration ; FIH ; first-in-humans ; hERG ; human ether-à ; -go-go-related gene ; hiPSC-CMs ; human induced pluripotent stem cell derived cardiomyocyte

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

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