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在“Elsevier电子期刊”中，命中：247条，耗时：0.0129913 秒

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1.Rational design, synthesis and in vitro evaluation of novel exo-methylene butyrolactone salicyloylamide as NF-κB inhibitor

作者：Kulrawee Sidthipong^a ; Jun Ma^b ; Wei Lin Yu^b ; Yan Feng Wang^b ; Susumu Kobayashi^c ; Satoshi Kishino^d ; Naoki Koide^e ; Takashi Yokochi^e ; Kuniki Kato^a ; Shoshiro Okada^f ; Kazuo Umezawa^a ; ^{umezawa@aichi-med-u.ac.jp}

关键词：(&minus ; )-DHMEQ ; Cysteine ; NF-κB ; α-Exomethylene-γ-lactone ; Bioconjugate

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation

作者：Jae-Gyu Kim^a ; Hyung-Joo Kwon^b ; ^c ; Guang Wu^c ; Yohan Park^a ; Jae-Yong Lee^a ; ^d ; Jaebong Kim^a ; ^d ; Sung-Chan Kim^a ; ^d ; Myoen Choe^e ; Seung Goo Kang^f ; Goo-Young Seo^g ; Pyeung-Hyeun Kim^g ; Jae-Bong Park^a ; ^c ; ^d ; ^{jbpark@hallym.ac.kr}

关键词：CA ; constitutively active ; DMEM ; Dulbecco's modified Eagle's medium ; DN ; dominant negative ; GAP ; GTPase activating protein ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; GDF ; GDI displacement factor ; GDI ; guanine nucleotide dissociation inhibitor ; GEF ; guanine nucleotide exchange factor ; GSH ; glutathione ; Rhotekin-RBD ; Rhotekin Rho-binding domain ; ROCK ; Rho-dependent coiled-coil kinase ; ROS ; reactive oxygen species ; WT ; wild-type ; NF-κB ; nuclear factor-κB ; IκB ; inhibitor of NF-κB ; IKK ; IκB ki

刊名：Free Radical Biology and Medicine

出版年：2017

3.Maspin inhibits macrophage phagocytosis and enhances inflammatory cytokine production via activation of NF-κB signaling

作者：Yimeng Wang^a ; ^b ; Luguo Sun^b ; Zhenbo Song^a ; ^c ; Danfeng Wang^a ; ^b ; Yongli Bao^a ; ^{baoyl800@nenu.edu.cn} ; Yuxin Li^b ; ^c ; ^{liyx486@nenu.edu.cn}

关键词：Arg-1 ; arginase 1 ; CM ; conditioned medium ; FITC ; fluorescein isothiocyanate ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; iNOS ; inducible nitric oxide synthase ; IFN ; interferon ; IKK ; inhibitor of NF-κB kinase ; IκB ; inhibitor of NF-κB ; LPS ; lipopolysaccharide ; Mφ ; macrophage ; NBS ; neonatal bovine serum ; PDTC ; pyrrolidine dithiocarbamate ; rMaspin ; recombinant Maspin ; SEM ; standard error of the mean

刊名：Molecular Immunology

出版年：2017

4.IκB kinase inhibition as a potential treatment of osteoarthritis - results of a clinical proof-of-concept study

作者：K. Grothe^&dagger ; ; ^{Kirsten.Grothe@sanofi.com} ; K. Flechsenhar^&dagger ; ; ^{Klaus.Flechsenhar@sanofi.com} ; T. Paehler^&Dagger ; ; ^{Tobias.Paehler@sanofi.com} ; O. Ritzeler^§ ; ; ^{Olaf.Ritzeler@sanofi.com} ; J. Beninga^‖ ; ^{Jochen.Beninga@sanofi.com} ; J. Saas^&dagger ; ; ^{Joachim.Saas@sanofi.com} ; M. Herrmann^&dagger ; ; ^{Matthias.Herrmann@sanofi.com} ; K. Rudolphi^&dagger ; ; ^{Karl.Rudolphi@sanofi.com}

关键词：IκB kinase inhibitor ; Slow-release formulation ; Intra-articular injection ; Treatment of knee osteoarthritis ; Clinical findings

刊名：Osteoarthritis and Cartilage

出版年：2017

5.Class I histone deacetylases regulate p53/NF-κB crosstalk in cancer cells

作者：Claudia Schä ; fer^a ; Anja Gö ; der^b ; Mandy Beyer^b ; Nicole Kiweler^b ; Nisintha Mahendrarajah^b ; Anke Rauch^a ; Teodora Nikolova^b ; Natasa Stojanovic^c ; Martin Wieczorek^a ; Thomas R. Reich^b ; Maja T. Tomicic^b ; Michael Linnebacher^d ; Jü ; rgen Sonnemann^e ; Sascha Dietrich^f ; Andreas Sellmer^g ; Siavosh Mahboobi^g ; Thorsten Heinzel^a ; Gü ; nter Schneider^h ; ¹ ; Oliver H. Krä ; mer^b ; ¹ ; ^{okraemer@uni-mainz.de}

关键词：BCL ; B cell lymphoma ; CLL ; chronic lymphatic leukemia ; DSB ; DNA double strand break ; HDAC ; histone deacetylase ; HDACi ; histone deacetylase inhibitor ; MS-275 ; entinostat ; NF-κB ; nuclear factor &lsquo ; kappa-light-chain-enhancer&rsquo ; of activated B cells ; PDAC ; pancreatic ductal adenocarcinoma ; PTM ; posttranslational modification ; VPA ; valproic acid

刊名：Cellular Signalling

出版年：2017

6.Advanced glycation end products interfere with gastric smooth muscle contractile marker expression via the AGE/RAGE/NF-κB pathway

作者：Ting Yu¹ ; Yongping Zheng¹ ; Yun Wang ; Wenjie Xiong ; Lin Lin ; ^{linlin9100@aliyun.com}

关键词：AGE ; advanced glycation end products ; SM ; smooth muscle ; RAGE ; advanced glycation end products receptor ; SMCs ; smooth muscle cells ; NF-κB ; nuclear factor-κB ; CML ; Nε-(carboxymethyl) lysine ; MHC ; myosin heavy chains ; GI ; gastrointestinal ; SD ; Sprague-Dawley ; STZ ; streptozotocin ; CCh ; carbachol ; HRP ; horseradish peroxidase ; PBS ; phosphate-buffered saline ; STZ-D ; STZ-induced diabetic ; DAB ; 3 ; 3-diaminobenzidin ; ROI ; region of interest ; SM-22α ; 22 ; kDa smooth muscle protein

刊名：Experimental and Molecular Pathology

出版年：2017

7.Rho-kinase inhibitor treatment prevents pulmonary inflammation and coagulation in lipopolysaccharide-induced lung injury

作者：Renyu Ding ; ^{renyuding@126.com} ; Dongmei Zhao ; Xiaoxia Li ; Baoyan Liu ; Xiaochun Ma ; ^{xcma2972@sina.com}

关键词：Acute lung injury ; (ALI) ; Lipopolysaccharide ; (LPS) ; Human pulmonary microvascular endothelial cells ; (HPMECs) ; Myeloperoxidase ; (MPO) ; Interleukins 1-beta ; (IL-1β) ; Interluekin-6 ; (IL-6) ; Nuclear factor ; ((NF)-κB.) ; Tumor necrosis factor ; (TNF)-α ; Tissue factor ; (TF) ; Plasminogen activator inhibitors ; (PAIs) ; Bronchoalveolar lavage fluid ; (BALF) ; Enzyme-linked immunosorbent assay ; (ELISA) ; Radioimmunoprecipitation assay ; (RIPA) ; Real-time polymerase chain reaction ; (qPCR) ; Dimethylarginine dime

刊名：Thrombosis Research

出版年：2017

8.Simultaneous Inhibition of PI3Kδ and PI3Kα Induces ABC-DLBCL Regression by Blocking BCR-Dependent and -Independent Activation of NF-κB and AKT

作者：Juliane Paul¹ ; ⁵ ; Maurice Soujon¹ ; ⁵ ; Antje M. Wengner¹ ; Sabine Zitzmann-Kolbe¹ ; Andrea Sturz¹ ; Katja Haike¹ ; Koh Hui Keng Magdalene² ; Sze Huey Tan³ ; Martin Lange¹ ; Soo Yong Tan² ; ⁶ ; Dominik Mumberg¹ ; Soon Thye Lim⁴ ; Karl Ziegelbauer¹ ; Ningshu Liu¹ ; ^{ningshu.liu@bayer.com}

关键词：PI3Kα ; PI3Kδ ; NF-κB ; BCR ; MYD88 ; CARD11 ; DLBCL ; follicular lymphoma ; ibrutinib-resistance ; copanlisib

刊名：Cancer Cell

出版年：2017

9.Saponin fraction isolated from Conyza blinii H.Lév. demonstrates strong anti-cancer activity that is due to its NF-κB inhibition

作者：Long Ma^a ; ^b ; ^{woshimalong1983@163.com} ; ^{malong@tust.edu.cn} ; Haiyan Liu^a ; Ping Qin^a ; Chenxi Hu^a ; Shuli Man^a ; Yuyin Li^a ; Zhen Liu^a ; Zhenxing Liu^a ; Aipo Diao^a ; ^b ; ^{diaoaipo@tust.edu.cn}

关键词：Saponin ; Conyza blinii H.Lé ; v. ; Traditional Chinese medicine (TCM) ; Anti-Cancer activity ; Apoptosis ; NF-κB inhibition

刊名：Biochemical and Biophysical Research Communications

出版年：2017

10.Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca²⁺-NFATc1 signaling pathway and prevents ovariectomy-induced bone loss

作者：Xiangzhou Zeng^a ; ^b ; Yueyang Zhang^a ; Song Wang^c ; Keng Wang^a ; Lei Tao^a ; Min Zou^a ; Nana Chen^a ; Jiake Xu^d ; Shuwen Liu^a ; ^{liusw@smu.edu.cn} ; Xiaojuan Li^a ; ^{lixiaoj@smu.edu.cn}

关键词：Art ; artesunate ; RANKL ; receptor activator of nuclear factor-κB (NF-κB) ligand ; M-CSF ; macrophage colony-stimulating factor ; TRAP ; tartrate-resistant acid phosphatase ; TRAF6 ; tumor necrosis factor receptor associated factor 6 ; IκB ; inhibitor of nuclear factor-κB ; NF-κB ; nuclear factor-κB ; NFATc1 ; nuclear factor of activated T cells c1 ; Micro-CT ; microcomputer tomography

刊名：Biochemical Pharmacology

出版年：2017

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