搜索页_ insulin/insulin-like growth factor signaling pathway

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在“Elsevier电子期刊”中，命中：1,626条，耗时：0.1259105 秒

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1.Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

作者：Natasha B. Leighl¹ ; Naiyer A. Rizvi² ; Lopes Gilberto de Lima Jr.³ ; ⁴ ; Wichit Arpornwirat⁵ ; Charles M. Rudin⁶ ; Alberto A. Chiappori⁷ ; Myung-Ju Ahn⁸ ; Laura Q.M. Chow⁹ ; Lyudmila Bazhenova¹⁰ ; Arunee Dechaphunkul¹¹ ; Patrapim Sunpaweravong¹² ; Keith Eaton¹³ ; ¹⁴ ; Jihong Chen¹⁵ ; Sonja Medley¹⁵ ; Srinivasu Poondru¹⁵ ; Margaret Singh¹⁵ ; Joyce Steinberg¹⁵ ; Rosalyn A. Juergens¹⁶ ; ^{juergensr@hhsc.ca} ; Shirish M. Gadgeel¹⁷ ; ¹⁸

关键词：Combination ; Epidermal growth factor receptor inhibitor ; First-line therapy ; Insulin-like growth factor-1 inhibitor ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

2.De novo transcriptome analysis reveals insights into different mechanisms of growth and immunity in a Chinese soft-shelled turtle hybrid and the parental varieties

作者：Haiqi Zhang^a ; ^b ; ^{zmk407@126.com} ; Xiaojun Xu^b ; ^{24587980@qq.com} ; Zhongyang He^b ; ^{zjscxpz@126.com} ; Tianlun Zheng^b ; ^{tlzheng@126.com} ; Jianzhong Shao^a ; ^{shaojz@zju.edu.cn}

关键词：AGBL2 ; ATP/GTP binding protein-like 2 ; BMPR1A ; Bone morphogenetic protein receptor ; type 1A ; CLEC3B ; C-type lectin domain family 3 ; C1QTNF1 ; C1q and tumor necrosis factor related protein1 ; DDAH1 ; Dimethylarginine dimethylaminohydrolase 1 ; DEGs ; Differentially expressed genes ; DHA ; Docosahexaenoic acid ; ECSIT ; Evolutionary conserved signaling intermediate in Toll pathway ; EPA ; Eicosapentaenoic acid ; GABRG2 ; Gamma-aminobutyric acid A receptor ; GDA ; Guanine deaminase ; GH ; Growth hormone ; GHITM ; Gro

刊名：Gene

出版年：2017

3.Insulin-like growth factor-1 protects SH-SY5Y cells against β-amyloid-induced apoptosis via the PI3K/Akt-Nrf2 pathway

作者：Zigao Wang^a ; ^b ; ¹ ; Lu Xiong^c ; ¹ ; Guanqun Wang^b ; ^d ; Wenbin Wan^a ; Chunjiu Zhong^a ; Hengbing Zu^b ; ^{hbzyy8@sina.com}

关键词：IGF-1 ; β-amyloid ; Apoptosis ; Oxidative stress ; PI3K/Akt ; Nrf2

刊名：Experimental Gerontology

出版年：2017

4.Silencing IGF-II impairs C-myc and N-ras expressions of SMMC-7721 cells via suppressing FAK/PI3K/Akt signaling pathway

作者：Yuanyuan Ji^a ; Zhidong Wang^b ; ^{xawzd@163.com} ; Zongfang Li^c ; Na Huang^a ; Haiyan Chen^a ; Baohua Li^a ; Bo Hui^b

关键词：Hepatocellular carcinoma (HCC) ; Insulin-like growth factor -II (IGF-II) ; C-myc ; N-ras ; Proliferation

刊名：Cytokine

出版年：2017

5.Activation of the Tor/Myc signaling axis in intestinal stem and progenitor cells affects longevity, stress resistance and metabolism in drosophila

作者：Olha M. Strilbytska^a ; Uliana V. Semaniuk^a ; Kenneth B. Storey^b ; Bruce A. Edgar^c ; Oleh V. Lushchak^a ; ^{olehl@pu.if.ua}

关键词：AKH ; adipokinetic hormone ; CAFE ; capillary feeding assay ; DILP ; Drosophila insulin-like peptide ; EB ; enteroblast ; EC ; enterocyte ; EE ; enteroendocrine cell ; EGFR ; epidermal growth factor receptor ; ISC ; intestinal stem cell ; JAK/STAT ; Janus kinase and signal transducer and activator of transcription ; PEPCK ; phosphoenolpyruvate carboxykinase ; ROS ; reactive oxygen species ; Su(H) ; suppressor of hairless ; S6K ; kinase of S6 protein ; TAG ; triglycerides ; TOR ; target of rapamycin ; TSC ; tuberous sclerosis

刊名：Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

出版年：2017

6.Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond

作者：Mary Nakazawa ; Natasha Kyprianou ; ^{nkypr2@uky.edu}

关键词：ADT ; Androgen deprivation therapy ; AR ; Androgen receptor ; CRPC ; Castration resistant prostate cancer ; DHT ; Dihydrotestosterone ; EGF ; Epidermal growth factor ; EMT ; Epithelial mesenchymal transition ; ERβ ; Estrogen receptor β ; FGF ; Fibroblast growth factor ; IGF ; Insulin-like growth factor ; MET ; Mesenchymal epithelial transition ; PDGF ; Platelet derived growth factor ; PI3 K ; Phosphatidylinositol 3-OH kinase ; PTEN ; Phosphatase tensin homolog ; RTK ; Receptor tyrosine kinase ; SHH ; Sonic Hedgehog ; TGFβ ; T

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

7.Statin suppresses Hippo pathway-inactivated malignant mesothelioma cells and blocks the YAP/CD44 growth stimulatory axis

作者：Kosuke Tanaka^a ; ^b ; ^c ; Hirotaka Osada^a ; ^b ; Yuko Murakami-Tonami^a ; Yoshitsugu Horio^c ; Toyoaki Hida^c ; Yoshitaka Sekido^a ; ^b ; ^{ysekido@aichi-cc.jp}

关键词：Statin ; CD44 ; Hippo pathway ; YAP ; Cancer stem cell ; Malignant mesothelioma

刊名：Cancer Letters

出版年：2017

8.Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes

作者：Akihiro Nagano^a ; ^b ; ¹ ; Masaki Arioka^a ; ¹ ; Fumi Takahashi-Yanaga^a ; ^c ; ^{yanaga@clipharm.med.kyushu-u.ac.jp} ; Etsuko Matsuzaki^b ; ^d ; Toshiyuki Sasaguri^a

关键词：Osteoblast ; Celecoxib ; Wnt/β-catenin signaling pathway ; Mineralization ; Fracture healing

刊名：Journal of Pharmacological Sciences

出版年：2017

9.Hesperidin derivative-11 inhibits fibroblast-like synoviocytes proliferation by activating Secreted frizzled-related protein 2 in adjuvant arthritis rats

关键词：Hesperidin (PubChem CID ; 53477767) ; Formaldehyde (PubChem CID ; 712) ; Acetone (PubChem CID ; 180) ; Triton X-100(PubChem CID ; 5590) ; Ethylene Diamine Tetraacetic Acid (PubChem CID ; 6049)

刊名：European Journal of Pharmacology

出版年：2017

10.Phospholipase Cγ in Toll-like receptor-mediated inflammation and innate immunity

作者：Yoe-Sik Bae^a ; ^b ; ^{yoesik@skku.edu} ; Ha Young Lee^a ; Young Su Jung^a ; Mingyu Lee^b ; Pann-Ghill Suh^c

刊名：Advances in Biological Regulation

出版年：2017

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