搜索页_+ligand+binding+assay

常用资源

电子图书

期刊论文

学位会议

外文资源

特色专题

内部出版物

Wiley电子期刊(70)	SpringerLink电子期刊(851)	NATURE电子期刊(23)	ACS电子期刊(1056)
Springer电子图书(13)	ProQuest学位论文(1)	Elsevier电子期刊(3889)

在“Elsevier电子期刊”中，命中：3,889条，耗时：0.0869604 秒

在所有数据库中总计命中：5,903条

1.Bivalent kinetic binding model to surface plasmon resonance studies of antigen-antibody displacement reactions

作者：Dagmar Gelinsky-Wersing^a ; Wolfram Wersing^b ; ¹ ; ^{wolfram.wersing@t-online.de} ; Wolfgang Pompe^a

关键词：Small molecule sensor ; SPR detection ; Protein interaction ; Ligand binding ; Kinetic rate constants ; Kinetic simulation

刊名：Analytical Biochemistry

出版年：2017

2.Drug-protein binding of Danhong injection and the potential influence of drug combination with aspirin: Insight by ultrafiltration LC-MS and molecular modeling

作者：Junfeng Zhu ; Xiaojiao Yi ; Peng Huang ; Shuqing Chen ; Yongjiang Wu ; ^{yjwu@zju.edu.cn}

关键词：Drug-protein binding ; Danhong injection ; Aspirin ; Human serum albumin ; Ultrafiltration LC&ndash ; MS ; Molecular modeling

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2017

3.An aptamer-based effective method for highly sensitive detection of chloramphenicol residues in animal-sourced food using real-time fluorescent quantitative PCR

作者：Ye Duan^a ; ¹ ; Lihui Wang^a ; ¹ ; Zhiqiang Gao^b ; Huishan Wang^c ; Hexiao Zhang^b ; ^{zhanghx@bjciq.gov.cn} ; Hao Li^a ; ^{lihao@mail.buct.edu.cn} ; ^{lihaoh@163.com}

关键词：B&W ; washing and binding ; CAP ; chloramphenicol ; Ct ; cycle threshold ; dsDNA ; double stranded DNA ; ELISA ; enzyme linked immunosorbent assay ; EU ; European Union ; FF ; florfenicol ; FRET ; fluorescence resonance energy transfer ; GC ; gas chromatography ; LC ; liquid chromatography ; LC-MS ; liquid chromatography mass spectrometry ; LOD ; limit of detection ; MRPL ; minimum required performance limit ; qRT-PCR ; real-time fluorescent quantitative PCR ; SELEX ; systematic evolution of ligands by exponential enrichmen

刊名：Talanta

出版年：2017

4.Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

作者：Jeanne G. Quirit^a ; ^{jgquirit@berkeley.edu} ; Sergey N. Lavrenov^b ; ^{satory@mail.ru} ; Kevin Poindexter^a ; ^{kpoindexter25@gmail.com} ; Janice Xu^a ; ^{jamicexu@scripps.edu} ; Christine Kyauk^a ; ^{ckyauk@berkeley.edu} ; Kathleen A. Durkin^c ; ^{durkin@berkeley.edu} ; Ida Aronchik^a ; ^{idaaronchik@gmail.com} ; Thomas Tomasiak^d ; ^{tomasiak@msg.ucsf.edu} ; Yaroslav A. Solomatin^b ; ^{hercules44@yandex.ru} ; Maria N. Preobrazhenskaya^b ; ^{satory@mail.ru} ; Gary L. Firestone^a ; ^{glfire@berkeley.edu}

关键词：Indole-3-carbinol analogues ; Ligand-target protein interactions ; NEDD4-1 ubiquitin ligase ; In silico computational modeling ; Anti-cancer compounds ; Melanoma cells

刊名：Biochemical Pharmacology

出版年：2017

5.Interaction between bioactive compound 11a-N-tosyl-5-deoxi-pterocarpan (LQB-223) and Calf thymus DNA: Spectroscopic approach, electrophoresis and theoretical studies

作者：Marina M. Silva^a ; Eduarda O.O. Nascimento^a ; Edeí ; ldo F. Silva Jú ; nior^a ; Joã ; o Xavier de Araú ; jo Jú ; nior^a ; ^b ; Camilla C. Santana^b ; Luciano Aparecido M. Grillo^b ; Rafaela S. de Oliveira^c ; Paulo R.R.Costa^d ; Camilla D. Buarque^c ; Josué ; Carinhanha C. Santos^a ; ¹ ; ^{josue@iqb.ufal.br} ; ^{jcarinhanha@yahoo.com.br} ; Isis M. Figueiredo^a ; ¹ ; ^{figueiredo.isis@gmail.com}

关键词：11a-N-tosyl-5-carbapterocarpan ; 11a-N-arylsulfonyl-tetrahydro-5H-benzo[a]carbazole ; CT DNA interaction ; Spectroscopic techniques ; Theoretical studies ; Electrophoresis

刊名：International Journal of Biological Macromolecules

出版年：2017

6.Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRα from Drugbank database

作者：Dan Xu¹ ; ^a ; Lijun Cai¹ ; ^a ; Shangjie Guo^a ; Lei Xie^a ; Meimei Yin^a ; Ziwen Chen^a ; Hu Zhou^a ; Ying Su^a ; ^b ; Zhiping Zeng^a ; ^{zengzhiping@xmu.edu.cn} ; Xiaokun Zhang^a ; ^b ; ^{xkzhang@xmu.edu.cn}

关键词：RXRα ; Old drug ; Agonist ; Antagonist ; Virtual screening

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Benzoflavones as cholesterol esterase inhibitors: Synthesis, biological evaluation and docking studies

作者：Harbinder Singh^a ; Jatinder Vir Singh^a ; Manish K. Gupta^b ; Palwinder Singh^c ; Sahil Sharma^a ; ^{ss.gq2009@gmail.com} ; Kunal Nepali^a ; ; Preet Mohinder S. Bedi^a ;

关键词：Benzoflavone ; Baker Venkataraman rearrangement ; Cholesterol esterase inhibition ; Enzyme kinetics ; Docking studies

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

8.Resistin promotes CCL4 expression through toll-like receptor-4 and activation of the p38-MAPK and NF-κB signaling pathways: implications for intervertebral disc degeneration

作者：Z. Li^&dagger ; ; ^a ; X. Wang^&Dagger ; ; ^a ; H. Pan^&dagger ; ; H. Yang^‖ ; X. Li^&dagger ; ; K. Zhang^§ ; ; H. Wang^&dagger ; ; Z. Zheng^&dagger ; ; H. Liu^&dagger ; ; ^{hippocratez@163.com} ; J. Wang^&dagger ; ; ^{zzuwjr@163.com}

关键词：Resistin ; Chemokine ; CCL4 ; Intervertebral disc ; Nucleus pulposus

刊名：Osteoarthritis and Cartilage

出版年：2017

9.A lifetime-sensitive fluorescence anisotropy probe for DNA-based bioassays: The case of SYBR Green

作者：Benoit Chovelon^a ; ^b ; ^c ; Emmanuelle Fiore^a ; ^b ; Patrice Faure^c ; ^d ; Eric Peyrin^a ; ^b ; ^{eric.peyrin@ujf-grenoble.fr} ; Corinne Ravelet^a ; ^b ; ^{corinne.ravelet@ujf-grenoble.fr}

关键词：Fluorescence anisotropy ; SYBR Green ; Lifetime ; DNA oligonucleotide ; Wide applicability

刊名：Biosensors and Bioelectronics

出版年：2017

10.Homogeneous time-resolved G protein-coupled receptor-ligand binding assay based on fluorescence cross-correlation spectroscopy

作者：Thomas Antoine^a ; ¹ ; David Ott^a ; ¹ ; Katharina Ebell^a ; Kerrin Hansen^a ; Luc Henry^b ; Frank Becker^a ; Stefan Hannus^a ; ^{stefan.hannus@intana.de" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCR ; Homogeneous time-resolved binding assay ; Fluorescence correlation spectroscopy ; Fluorescence cross-correlation spectroscopy ; Affinity determination ; Binding kinetics

刊名：Analytical Biochemistry

出版年：2016

按检索点细分(3889)

题名(64)

关键词(82)

文摘(3364)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700