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在“Elsevier电子期刊”中，命中：940条，耗时：0.0459749 秒

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1.Effect on catecholase activity and interaction with biomolecules of metal complexes containing differently tuned 5-substituted ancillary tetrazolato ligands

作者：Manideepa Saha ; Novina Malviya ; Mriganka Das ; Indrani Choudhuri ; Shaikh M. Mobin ; Biswarup Pathak ; Suman Mukhopadhyay ; ^{suman@iiti.ac.in}

关键词：Metal tetrazolato complexes ; Catecholase like activity ; DNA binding ; Protein binding ; DFT study

刊名：Polyhedron

出版年：2017

2.DNA-duplex linker for AFM-SELEX of DNA aptamer against human serum albumin

作者：Musashi Takenaka ; Yuzo Okumura ; Tomokazu Amino ; Yusuke Miyachi ; Chiaki Ogino ; ^{ochiaki@port.kobe-u.ac.jp} ; Akihiko Kondo

关键词：SELEX ; Atomic force microscope ; DNA aptamer ; Human serum albumin

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.TPP riboswitch characterization in Alishewanella tabrizica and Alishewanella aestuarii and comparison with other TPP riboswitches

作者：Elnaz Mehdizadeh Aghdam^a ; ^b ; ^c ; Malte Sinn^d ; Vahideh Tarhriz^a ; Abolfazl Barzegar^e ; ^f ; Jö ; rg S. Hartig^d ; ^{joerg.hartig@uni-konstanz.de} ; Mohammad Saeid Hejazi^a ; ^b ; ^{saeidhejazi@tbzmed.ac.ir} ; ^{msaeidhejazi@yahoo.com}

关键词：Alishewanella tabrizica ; Thiamine pyrophosphate ; Riboswitch ; In-line probing ; SPR

刊名：Microbiological Research

出版年：2017

4.A method for measuring binding constants using unpurified in vivo biotinylated ligands

作者：Anastassia K. Pogoutse^a ; ¹ ; Christine Chieh-Lin Lai^a ; ¹ ; Nicholas Ostan^b ; Rong-hua Yu^b ; Anthony B. Schryvers^b ; Trevor F. Moraes^a ; ^{trevor.moraes@utoronto.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：Bio-layer interferometry (BLI) ; Biomolecular interactions ; Dissociation constant (KD) ; Lysate ; In vivo biotinylation ; BirA

刊名：Analytical Biochemistry

出版年：2016

5.A new, simple and robust radioligand binding method used to determine kinetic off-rate constants for unlabeled ligands. Application at α_2A- and α_2C-adrenoceptors

作者：Staffan Uhlé ; n^a ; ^b ; ^{staffan.uhlen@neuro.uu.se" class="auth_mail" title="E-mail the corresponding author} ; Helgi B. Schiö ; th^b ; Jan Anker Jahnsen^a

关键词：Spiroxatrine ; MK912 ; Off-rate ; Residence time ; [3H]-RX821002 ; Kinetics

刊名：European Journal of Pharmacology

出版年：2016

6.Kinetic speciation of mercury-humate complexes in aqueous solutions by using competing ligand exchange method

作者：Krushna Vudamala¹ ; Parthasarathi Chakraborty ; ¹ ; ^{pchak@nio.org" class="auth_mail" title="E-mail the corresponding author}

关键词：Mercury speciation ; Competing ligand exchange method ; Dynamic complexes ; Dissociation rate constant ; Ambersep GT74 ; Dissolved organic carbon

刊名：Microchemical Journal

出版年：2016

7.Fragment-based discovery of inhibitor scaffolds targeting the metallo-β-lactamases NDM-1 and VIM-2

作者：Tony Christopeit ; Hanna-Kirsti S. Leiros ; ^{hanna-kirsti.leiros@uit.no" class="auth_mail" title="E-mail the corresponding author}

关键词：FBDD ; fragment based drug discovery ; MBL ; metallo-β-lactamase ; PAINS ; Pan Assay Interference Compounds ; SBL ; serine-β-lactamases ; NDM ; New Delhi metallo-β-lactamase ; VIM ; Verona integron-encoded metallo-β-lactamase ; IMP ; Imipenemase ; SPR ; surface plasmon resonance ; ka ; on-rate ; kd ; off-rate ; KD ; dissociation constant ; QM ; quantum mechanics ; QPLD ; QM-polarized ligand docking

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein

作者：Kaitlyn V. Ledwitch ; Morgan E. Gibbs ; Robert W. Barnes ; Arthur G. Roberts ; ^{audie@uga.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AMPPNP ; adenosine 5&prime ; -(β ; γ-imido)triphosphate ; COPASI ; complex pathway simulator ; DDM ; n-dodecyl-β-d-maltoside ; F0H ; initial fluorescence intensity at the high concentration phase ; F0L ; initial fluorescence intensity at the low concentration phase ; KA ; association constant ; KD ; dissociation constant ; KH ; equilibrium constant at high concentration ; KL ; equilibrium constant at low concentration ; KSV ; Stern-Volmer quenching constant ; L ; ligand ; NTA ; nickel-nitrilotriacetic acid ; PAGE ; polyac

刊名：Biochemical Pharmacology

出版年：2016

9.Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data

作者：Lisa A. Stott^a ; David A. Hall^b ; Nicholas D. Holliday^a ; ^{nicholas.holliday@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; concentration response curve ; EC50 ; effective agonist concentration for 50% maximum response ; Emax ; maximum system response ; GPCR ; G protein coupled receptor ; D2R ; dopamine D2 receptor ; GTPγS ; guanosine 5&prime ; -O-[γ-thio]triphosphate ; KA ; agonist equilibrium dissociation constant ; KE ; concentration of agonist&ndash ; receptor complex which produces a half maximal effect ; MAPK ; mitogen activated protein kinase ; RAi ; relative intrinsic activity ratio ; Rmax ; maximum agonist response ; RT ; total

刊名：Biochemical Pharmacology

出版年：2016

10.Equilibrium and kinetic selectivity profiling on the human adenosine receptors

作者：Dong Guo¹ ; Gabrielle S. Dijksteel ; Tirsa van Duijl ; Maxime Heezen ; Laura H. Heitman ; Adriaan P. IJzerman ; ^{ijzerman@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：ARs ; adenosine receptors ; CGS15943 ; 9-chloro-2-(2-furanyl)-[12 ; 4]triazolo [1 ; 5-c]quinazolin-5-amine ; CHAPS ; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate ; CPA ; N6-cyclopentyladenosine ; DPCPX ; 1 ; 3-dipropyl-8-cyclopentylxanthine ; IB-MECA ; N6-(3-Iodobenzyl)adenosine-5&prime ; -N-methyluronamide ; GPCR ; G protein-coupled receptor ; k1 ; the association rate constant of the radioligand ; k2 ; the dissociation rate constant of the radioligand ; k3 ; the association rate constant of the unlabeled l

刊名：Biochemical Pharmacology

出版年：2016

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