作者：Xihong Zhou^a ; ^b ; ^c ; ^d ; Dan Wan^a ; ^b ; ^c ; ^d ; ^{w.dan@isa.ac.cn} ; Yumei Zhang^e ; Yiming Zhang^a ; ^b ; ^c ; ^d ; Cimin Long^a ; ^b ; ^c ; ^d ; Shuai Chen^a ; ^b ; ^c ; ^d ; Liuqin He^a ; ^b ; ^c ; ^d ; Bie Tan^a ; ^b ; ^c ; ^d ; Xin Wu^a ; ^b ; ^c ; ^d ; ^{wuxin@isa.ac.cn} ; Yulong Yin^a ; ^b ; ^c ; ^d ; ^{yinyulong@isa.ac.cn}

关键词：Desaturase ; Elongase ; Pig ; Polyunsaturated fatty acid

刊名：Biochemical and Biophysical Research Communications

出版年：2017

作者：Mó ; nica Lopes-Marques^a ; ^b ; Rodrigo Ozó ; rio^a ; ^b ; Ricardo Amaral^c ; Douglas R. Tocher^d ; Ó ; scar Monroig^d ; ¹ ; ^{oscar.monroig@stir.ac.uk} ; L. Filipe C. Castro^a ; ^e ; ¹ ; ^{filipe.castro@ciimar.up.pt}

关键词：Arapaima gigas ; Fatty acid desaturase (Fads) ; Long-chain polyunsaturated fatty acids (LC-PUFAs) ; Teleosts ; Evolution

刊名：Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

出版年：2017

作者：Angela Oboh^a ; ^b ; Mó ; nica B. Betancor^a ; Douglas R. Tocher^a ; Oscar Monroig^a ; ^{oscar.monroig@stir.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Biosynthesis ; Clarias gariepinus ; Elongase ; Essential fatty acids ; Desaturase ; Long-chain polyunsaturated fatty acids

刊名：Aquaculture

出版年：2016

作者：L. Filipe C. Castro^a ; ^b ; Douglas R. Tocher^c ; Oscar Monroig^c ; ^{oscar.monroig@stir.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：aa ; amino acid ; ACP ; acyl carrier protein ; ALA ; α-linolenic acid (18 ; 3n-3) ; ARA ; arachidonic acid (20 ; 4n-6) ; BHT ; butylated hydroxytoluene ; cDNA ; complementary DNA ; CoA ; Coenzyme A ; DHA ; docosahexaenoic acid (22 ; 6n-3) ; ELOVL ; elongation of very long-chain fatty acid protein ; EPA ; eicosapentaenoic acid (20 ; 5n-3) ; ER ; endoplasmic reticulum ; FACES ; fatty acid chain elongation system ; FADS ; fatty acyl desaturase ; FAE1 ; fatty acid elongase 1 ; FAS ; fatty acid synthase ; HADC ; β-hydroxyacyl-CoA dehydras

刊名：Progress in Lipid Research

出版年：2016

作者：Wenxia Li¹ ; Zhengfu Feng¹ ; Xiaojun Song ; Wei Zhu ; ^{zhuw001@163.com" class="auth_mail" title="E-mail the corresponding author} ; Yanjiang Hu

关键词：Aj-ELOVL5 ; elongase gene of Apostichopus japonicus ; ALA ; α-linolenic acid ; C18 ; 3 n-3 ; ARA ; arachidonic acid ; C20 ; 4 n-6 ; DGLA ; dihomo-γ-linolenic acid ; C20 ; 3 n-6 ; DHA ; docosahexaenoic acid ; C22 ; 6 n-3 ; DPA ; docosapentaenoic acid ; C22 ; 5 n-3 ; EPA ; eicosapentaenoic acid ; C20 ; 5 n-3 ; GC&ndash ; MS ; gas chromatography&ndash ; mass spectrometry ; GLA ; γ-linolenic acid ; C18 ; 3 n-6 ; PUFA ; long chain polyunsaturated fatty acid ; qRT-PCR ; quantitative real-time polymerase chain reaction

刊名：Gene

出版年：2016

作者：Dizhi Xie^a ; ^b ; ¹ ; Fang Chen^a ; ^b ; ¹ ; Siyuan Lin^a ; Cuihong You^a ; Shuqi Wang^a ; Qinghao Zhang^a ; Ó ; scar Monroig^c ; Douglas R. Tocher^c ; Yuanyou Li^a ; ^{yyli@stu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Elovl5 ; Elovl4 ; LC-PUFA biosynthesis ; Scatophagus argus

刊名：Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

出版年：2016

作者：M.B. Betancor^a ; ^{m.b.betancor@stir.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; R.E. Olsen^b ; ^c ; D. Solstorm^b ; O.F. Skulstad^b ; D.R. Tocher^a

关键词：Omega  ; &minus ;   ; 3 long chain polyunsaturated fatty acids ; Atlantic salmon ; Land-locked ; Desaturases ; Elongases

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

作者：Chanikul Chutrakul ; Sukanya Jeennor ; Sarocha Panchanawaporn ; Pattsarun Cheawchanlertfa ; Sarinya Suttiwattanakul ; Mayura Veerana ; Kobkul Laoteng ; ^{laotengk@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{kobkul@biotec.or.th" class="auth_mail" title="E-mail the corresponding author}

关键词：LC-PUFAs ; long chain-polyunsaturated fatty acids ; DGLA ; dihomo-γ-linolenic acid ; GLA ; γ-linolenic acid ; PGE1 ; prostaglandin E1 ; PA ; palmitoleic acid ; OA ; oleic acid ; LA ; linoleic acid ; ARA ; arachidonic acid ; GAL1 ; β-galactosidase promoter ; PEG ; polyethylene glycol ; ALA ; α-linolenic acid ; STA ; stearidonic acid ; EPA ; eicosapentaenoic acid ; STC ; sorbitol ; Tris&ndash ; HCl ; CaCl2 solution ; TL ; total lipids ; TLC ; thin-layer chromatography ; NL ; neutral lipids ; FAMEs ; fatty acid methyl esters ; ETA ; eicos

刊名：Journal of Biotechnology

出版年：2016

作者：Y. Shi^a ; X. Sun^a ; Y. Sun^a ; L. Hou^a ; M. Yao^a ; K. Lian^b ; J. Li^c ; X. Lu^a ; L. Jiang^a ; ^{jianglingling1959@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ACOX1 ; acyl-CoA oxidase 1 ; AD ; Alzheimer&rsquo ; s disease ; Aβ ; β-amyloid peptide ; AβPP ; amyloid β precursor protein ; BACE1 ; β-secretase ; DBP ; D-bifunctional protein ; DM ; diabetes mellitus ; DHA ; docosahexenoic acid ; ELOVLs ; elongase of very long chain fatty acids ; EPA ; eicosapentenoic acid ; HO-1 ; heme oxygenase 1 ; HD ; high-fat diet ; IOD ; integrate optical density ; MDA ; malondialdehyde ; MWM ; Morris water maze ; NOX4 ; NADPH oxidase 4 ; ND ; normal pellet diet ; PBS ; phosphate-buffered saline ; STZ ; strep

刊名：Neuroscience

出版年：2016

作者：Greta Carmona-Antoñ ; anzas ^{gec1@stir.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Xiaozhong Zheng ^{xzheng@staffmail.ed.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Douglas R. Tocher ^{d.r.tocher@stir.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Michael J. Leaver ; ^{m.j.leaver@stir.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Aa ; Amino acid ; ARA ; Arachidonic acid ; bp ; Base pair ; DHA ; Docosahexaenoic acid ; ELOVL ; Fatty-acyl elongase ; EPA ; Eicosapentaenoic acid ; FAD ; Fatty-acyl desaturase ; FHM ; Fathead minnow ; LC-PUFA ; Long-chain polyunsaturated fatty acids ; LTR ; Long terminal repeat ; LXR ; Liver X receptor ; LXRE ; Liver X receptor response element ; Myr ; Million years ; NF-Y ; Nuclear transcription factor Y ; PUFA ; Polyunsaturated fatty acids ; RXR ; Retinoic X receptor ; SRE ; Sterol response element ; SREBP ; Sterol regulatory

刊名：Gene

出版年：2016