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在“Elsevier电子期刊”中，命中：1,125条，耗时：0.0180241 秒

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1.Mulberry fruit ameliorates Parkinson's-disease-related pathology by reducing α-synuclein and ubiquitin levels in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid model

作者：Pil Sung Gu^a ; ¹ ; Minho Moon^b ; ¹ ; Jin Gyu Choi^a ; Myung Sook Oh^a ; ^c ; ^{msohok@khu.ac.kr}

关键词：Mulberry fruit ; α-Synuclein ; Parkinson's disease ; 1-Methyl-4-phenyl-123 ; 6-tetrahydropyridine ; Probenecid

刊名：The Journal of Nutritional Biochemistry

出版年：2017

2.The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

作者：Jolanta Konieczny^a ; ^{koniecz@if-pan.krakow.pl} ; Anna Czarnecka^a ; ^&dagger ; ; Tomasz Lenda^a ; Kinga Kamińska^a ; Lucyna Antkiewicz-Michaluk^b

关键词：DA ; dopamine ; DOPAC ; dihydroxyphenylacetic acid ; HVA ; homovanilic acid ; MPP+ ; 1-methyl-4-phenylpyridinium ion ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; PD ; Parkinson&rsquo ; s disease ; SN ; substantia nigra ; SNc ; substantia nigra pars compacta ; SNr ; substantia nigra pars reticulata ; UPS ; ubiquitin&ndash ; proteasome system

刊名：Neuroscience

出版年：2017

3.Resveratrol attenuates MPP⁺-induced mitochondrial dysfunction and cell apoptosis via AKT/GSK-3β pathway in SN4741 cells

作者：Weijun Zeng^a ; ¹ ; Wei Zhang^b ; ^c ; ¹ ; Fangfang Lu^a ; Li Gao^a ; Guodong Gao^a ; ^{gaogd1954@163.com}

关键词：Res ; Resveratrol ; MPP+ ; 1-methyl-4-phenylpyridinium ; PD ; Parkinson&rsquo ; s disease ; GSK-3 ; Glycogen synthase kinase-3 ; GSK-3β ; Glycogen synthase kinase-3 beta ; AKT ; Protein kinase B ; MMP ; Mitochondrial membrane potential ; PI3K ; Phosphatidylinositol 3-kinase ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MTT ; 3-(4 ; 5-dimethylthiazol-2yl)-2 ; 5-diphenyltetrazolium bromide

刊名：Neuroscience Letters

出版年：2017

4.Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

作者：An-Guo Wu^a ; ¹ ; Wu Zeng^a ; ¹ ; Vincent Kam-Wai Wong^a ; Yi-Zhun Zhu^b ; Amy C.Y. Lo^c ; Liang Liu^a ; ^{lliu@must.edu.mo} ; Betty Yuen-Kwan Law^a ; ^{yklaw@must.edu.mo}

关键词：CHMs ; Chinese herbal medicines ; ATG ; autophagy-related proteins ; AD ; Alzheimer&rsquo ; s disease ; PD ; Parkinson&rsquo ; s disease ; AMPK ; 5&prime ; adenosine monophosphate-activated protein kinase ; mTOR ; mammalian target of rapamycin ; HD ; Huntington&rsquo ; s disease ; HH ; hedera helix ; PF ; petroleum ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; EF ; ethylacetate fraction ; HTT ; huntingtin ; NF ; n-butanol ; GFP ; green fluorescent protein ; PE ; phosphatidylethanolamine ; AHS ; acid hydrolyzed solution ; CM

刊名：Pharmacological Research

出版年：2017

5.Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein

作者：Yeomoon Sim^a ; Gunhyuk Park^a ; Hyeyoon Eo^b ; Eugene Huh^b ; ^c ; Pil Sung Gu^b ; Seon-Pyo Hong^b ; Youngmi Kim Pak^d ; Myung Sook Oh^a ; ^b ; ^{msohok@khu.ac.kr}

关键词：6-OHDA ; 6-hydroxydopamine ; DAT ; dopamine transporter ; ERK ; extracellular signal-regulated kinase ; HPLC ; high-performance liquid chromatography ; MABH ; herbal extract combination of Bupleuri Radix ; Moutan Cortex Radicis and Angelica Dahuricae Radix ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; Nurr1 ; nuclear receptor-related 1 protein ; PBS ; phosphate-buffered saline ; PD ; Parkinson&rsquo ; s disease ; ROP ; ropinirole ; SNpc ; substantia nigra pars compacta ; ST ; striatum ; TH ; tyrosine hydroxylase

刊名：Neuroscience

出版年：2017

6.Subcutaneous rotenone rat model of Parkinson's disease: Dose exploration study

作者：Zhen-Nian Zhang¹ ; Jing-Si Zhang¹ ; Jun Xiang ; Zhong-Hai Yu ; Wen Zhang ; Min Cai ; Xiang-Ting Li ; Ting Wu ; Wen-Wei Li ; Ding-Fang Cai ; ^{dingfangcai@163.com}

关键词：5-HT ; 5-hydroxytryptamine ; serotonin ; 6-OHDA ; 6-hydroxydopamine ; DA ; dopamine ; DOPAC ; dihydroxyphenylacetic acid ; EDTA ; ethylenediaminetetraacetic acid ; HPLC ; high performance liquid chromatography ; HVA ; homovanillic acid ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; PBS ; phosphate-buffered saline ; PD ; Parkinson's disease ; SNc ; substantia nigra pars compacta ; TH ; tyrosine hydroxylase ; MAO-B ; monoamine oxidase-B

刊名：Brain Research

出版年：2017

7.Enhanced dopaminergic neurotoxicity mediated by MPTP in IL-32β transgenic mice

作者：Yu Yeon Jung^a ; ^{hygienkh@naver.com} ; Nikita Katila^b ; ^{nikitakatila28@gmail.com} ; Sabita Neupane^b ; ^{sabita_neupane@hotmail.com} ; Sina Shadfar^b ; ^{sina.shadfar@yahoo.com} ; Uttam Ojha^b ; ^{uttamojha47@gmail.com} ; Sunil Bhurtel^b ; ^{bhurtelsunil11@gmail.com} ; Sunil Srivastav^b ; ^{sunsri2003@hotmail.com} ; Dong Ju Son^c ; ^{sondj1@chungbuk.ac.kr} ; Pil-Hoon Park^b ; ^{parkp@yu.ac.kr} ; Do Young Yoon^d ; ^{ydy4218@konkuk.ac.kr} ; Jin Tae Hong^c ; ^{jinthong@chungbuk.ac.kr} ; Dong-Young Choi^b ; ^{dychoi@yu.ac.kr}

关键词：Parkinson's disease ; Interleukin-32β ; Microglia ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine (MPTP) ; Neuroinflammation

刊名：Neurochemistry International

出版年：2017

8.Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson's disease

作者：Patrick K.K. Yeung^a ; Angela K.W. Lai^a ; Hyo Jin Son^b ; Xu Zhang^a ; Onyou Hwang^b ; Stephen S.M. Chung^c ; Sookja K. Chung^a ; ^d ; ^{skchung@hkucc.hku.hk}

关键词：Parkinson's disease ; Aldose reductase ; Knockout mice ; Oxidative stress

刊名：Neurobiology of Aging

出版年：2017

9.Neuroprotective mechanisms of plant extracts against MPTP induced neurotoxicity: Future applications in Parkinson’s disease

作者：Abdelrahman Ibrahim Abushouk^a ; ^b ; ^c ; Ahmed Negida^c ; ^d ; ^e ; Hussien Ahmed^c ; ^d ; ^e ; Mohamed M. Abdel-Daim^f ; ^{abdeldaim.m@vet.suez.edu.eg} ; ^{abdeldaim.m@gmail.com}

关键词：ASK-1 ; Apoptosis signal regulating kinase-1 ; BDNF ; Brain Derived Neurotrophic Factor ; CI ; Chrysanthemum indicum Linn ; DAT ; Dopamine transporter ; EGb761 ; Ginkgo biloba extract 761 ; EGCG ; Epigallocatechin-3-gallate ; GR ; Glutathione Reductase ; H2O2 ; Hydrogen peroxide ; HO-1 ; Heme-Oxygenase 1 ; JNK ; c-Jun NH2-terminal kinase ; LAMP-2A ; Lysosome associated membrane protein type 2A ; LC3-II ; Light chain 3- phosphatidylethanolamine conjugate ; MAPK ; mitogen activated protein kinases ; MDA ; Malondialdehyde ; M

刊名：Biomedicine & Pharmacotherapy

出版年：2017

10.2-Acetyl-7-hydroxy-6-methoxy-1-methyl-1,2,3,4,-tetrahydroisoquinoline exhibits anti-inflammatory properties and protects the nigral dopaminergic neurons

作者：Hyo Jin Son^a ; Se Hee Han^a ; Ji Ae Lee^a ; Cheol Soon Lee^b ; Jai Woong Seo^c ; Dae Yoon Chi^c ; ^d ; ^{dychi@sogang.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Onyou Hwang^a ; ^{oyhwang@amc.seoul.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：AMTIQ ; 2-acetyl-7-hydroxy-6-methoxy-1-methyl-1234 ; -tetarhydroisoquinoline ; BH4 ; tetrahydrobiopterin ; CYP ; cytochrome P450 ; DAergic ; dopaminergic ; ELISA ; enzyme-linked immuno sorbent assay ; GTPCH ; GTP cyclohydrolase I ; IL-1β ; interleukin-1β ; iNOS ; inducible NO synthase ; LPS ; lipopolysaccharide ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; NF-κB ; nuclear factor-κB ; NO ; nitric oxide ; PBS ; phosphate-buffered saline ; PD ; Parkinson&rsquo ; s disease ; PCR ; polymerase chain reaction ; RT ; reverse

刊名：European Journal of Pharmacology

出版年：2016

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