搜索页_ mitogen and extracellular signal activated kinase (mitogen activated kinase kinase)

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在“Elsevier电子期刊”中，命中：3,119条，耗时：0.044981 秒

在所有数据库中总计命中：3,987条

1.Expression and activation of platelet-derived growth factor β receptor, mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) and extracellular signal-regulated kinase (ERK) in canine mammary tumours

作者：Gennaro Altamura^a ; ^{gennaro.altamura@unina.it} ; Barbara degli Uberti^b ; ^{barbara.degliuberti@cert.izsmportici.it} ; Giorgio Galiero^b ; ^{giorgio.galiero@cert.izsmportici.it} ; Manuela Martano^a ; ^{manuela.martano@unina.it} ; Antonella Pirro^a ; ^{divas3@hotmal.it} ; Marco Russo^a ; ^{marco.russo@unina.it} ; Giuseppe Borzacchiello^a ; ^{borzacch@unina.it}

关键词：PDGFβR ; MEK ; ERK ; TKR inhibitors ; Oncology

刊名：Research in Veterinary Science

出版年：2017

2.Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation

作者：Wei Wu^a ; ^b ; Mahendra D. Chordia^c ; ^g ; Barry P. Hart^d ; E. Sathyajith Kumarasinghe^c ; Min K. Ji^c ; Ajay Bhargava^e ; Michael W. Lawlor^f ; Ji-Yeon Shin^a ; ^b ; Fusako Sera^a ; Shunichi Homma^a ; Antoine Muchir^a ; ^b ; ^h ; Uday R. Khire^c ; ^d ; ^{ukhire@allomek.com} ; Howard J. Worman^a ; ^b ; ^{hjw14@columbia.edu}

关键词：Cardiomyopathy ; Emery-Dreifuss muscular dystrophy ; Extracellular signal-regulated kinase ; Lamin ; MEK inhibitor ; Mitogen-activated protein kinase

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

3.Cigarette smoke extract induces epithelial-mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway

作者：Xin Sun^a ; ¹ ; Qifei Deng^b ; ¹ ; Zhaofeng Liang^c ; Zhiqi Liu^a ; Hao Geng^a ; Li Zhao^a ; Qirui Zhou^d ; Jie Liu^a ; Jiaxing Ma^a ; Daming Wang^a ; Dexin Yu^a ; ^{yudx_urology@126.com} ; Caiyun Zhong^e ; ^{cyzhong@njmu.edu.cn}

关键词：CSE ; Cigarette smoke extract ; CS ; Cigarette smoke ; EMT ; Epithelial&ndash ; mesenchymal transition ; MAPK ; Mitogen-activated protein kinase ; ERK1/2 ; extracellular regulated protein kinases 1 and 2 ; AP-1 ; activator protein 1 ; DMSO ; dimethyl sulfoxide ; MTT ; thiazolyl blue tetrazolium bromide ; qRT-PCR ; quantitative reverse transcription-polymerase chain reaction

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Polycyclic xanthones via pH-switched biotransformation of α-mangostin catalysed by horseradish peroxidase exhibited cytotoxicity against hepatoblastoma cells in vitro

作者：Jia-Jia Wu ^{wujiajia1045529@163.com} ; Ting Ma ^{maxueting0842910@163.com} ; Zhi-Min Wang ^{418973903@qq.com} ; Wen-Jun Xu ^{cpu_xuwenjun@163.com} ; Xue-Lian Yang ^{792697415@qq.com} ; Jian-Guang Luo ^{luojg@cpu.edu.cn} ; Ling-Yi Kong ; ^{cpu_lykong@126.com} ; Xiao-Bing Wang ; ^{xbwang@cpu.edu.cn}

关键词：HRP ; horseradish peroxidase ; MMP ; mitochondrial membrane potential ; PARP ; poly-(ADP-ribose)-polymerase ; ROS ; reactive oxygen species ; MAPK ; mitogen-activated protein kinase ; ERK ; extracellular signal-regulated kinase ; JNK ; c-Jun N-terminal kinases ; p38 ; p38 mitogen-activated protein kinase ; Bax ; Bcl-2 Associated X Protein ; Bcl-2 ; B cell lymphoma/lewkmia-2

刊名：Journal of Functional Foods

出版年：2017

5.Systematic Identification of Oncogenic EGFR Interaction Partners

作者：Julia Petschnigg¹ ; Max Kotlyar² ; Louise Blair¹ ; Igor Jurisica² ; ³ ; ⁴ ; ⁵ ; Igor Stagljar⁶ ; ⁷ ; ⁸ ; Robin Ketteler¹ ; ^{r.ketteler@ucl.ac.uk}

关键词：EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-regulated kinase ; GFP ; green fluorescent protein ; Grb2 ; growth factor receptor-bound protein 2 ; SH ; Src homology ; MAPK ; mitogen-activated protein kinase ; TK ; tyrosine kinase ; TKI ; TK inhibitor ; NSCLC ; non-small cell lung cancer ; MaMTH ; mammalian membrane two-hybrid ; TACC ; transforming acidic coiled-coil protein ; GO ; gene ontology ; Cub ; C-terminal half of ubiquitin ; TF ; transcription factor ; Nub ; N-ter

刊名：Journal of Molecular Biology

出版年：2017

6.N-Acetyl-chitobiose ameliorates metabolism dysfunction through Erk/p38 MAPK and histone H3 phosphorylation in type 2 diabetes mice

作者：Xia Wu^a ; Jing Wang^b ; Yuqin Shi^b ; Sai Chen^a ; Qiaojuan Yan^a ; Zhengqiang Jiang^b ; ^{zhqjiang@cau.edu.cn} ; Hao Jing^b

关键词：ALX ; alloxan ; COS ; chitooligosaccharide ; Erk ; extracellular signal-regulated kinase ; (GlcNAc)2 ; N-acetyl-chitobiose (PubChem CID ; 160244) ; H&E ; haematoxylin and eosin ; HOMA-IR ; homeostasis model assessment of insulin resistance ; IC50 ; the 50% inhibitory concentration ; IL-1β ; interleukin-1 beta ; JNK ; c-Jun terminal kinase ; MAPK ; mitogen-activated protein kinase ; MDA ; malondialdehyde ; MKK ; MAPK kinases ; MSK ; mitogen and stress activated protein kinase ; NF-κB ; nuclear factor-kappaB ; SOD ; superoxide

刊名：Journal of Functional Foods

出版年：2017

7.Acute arsenic exposure induces inflammatory responses and CD4⁺ T cell subpopulations differentiation in spleen and thymus with the involvement of MAPK, NF-kB, and Nrf2

作者：Xiaoxu Duan^a ; ¹ ; Shuang Gao^b ; ¹ ; Jinlong Li^a ; Liuzhong Wu^c ; Yang Zhang^a ; Wei Li^a ; Lu Zhao^a ; Jinli Chen^a ; Shan Yang^a ; Guifan Sun^a ; Bing Li^a ; ^{bli10@cmu.edu.cn}

关键词：TNF-α ; tumor necrosis factor α ; ROS ; reactive oxygen species ; NF-kB ; nuclear factor kappa B ; MAPK ; mitogen-activated protein kinase ; ERK1/2 ; extracellular-signal-regulated kinases 1/2 ; JNK ; c-Jun N-terminal kinases ; Nrf2 ; nuclear factor E2-related factor 2 ; Gata3 ; GATA-binding protein 3 ; IFN-γ ; interferon gamma ; HO-1 ; heme oxygenase-1 ; MPO ; myeloperoxidase ; MDA ; malondialdehyde ; H2O2 ; hydrogen peroxide ; CAT ; catalase ; GSH-Px ; glutathione peroxidase ; GST ; glutathione-S-transferase ; Treg cells ; re

刊名：Molecular Immunology

出版年：2017

8.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

9.Regulation of proteasome activity by P2Y₂ receptor underlies the neuroprotective effects of extracellular nucleotides

作者：Laura de Diego-Garcí ; a^a ; ^c ; Mercedes Ramí ; rez-Escudero^a ; Á ; lvaro Sebastiá ; n-Serrano^a ; ^c ; Juan Ignacio Diaz-Herná ; ndez^a ; ^d ; Jesú ; s Pintor^b ; José ; J. Lucas^d ; ^e ; Miguel Dí ; az-Herná ; ndez^a ; ^c ; ^{migueldiaz@ucm.es}

关键词：UPS ; Ubiquitin-Proteasome System ; P2Y2R ; P2Y2 receptor ; IP3 ; inositol 14 ; 5-trisphosphate ; MEK1/2 ; MAP kinase kinases ; ERK ; extracellular signal-regulated kinase ; PKC ; protein kinase C ; PKA ; protein kinase A ; PI3K ; inositol 14 ; 5-trisphosphate 3-kinases ; MAPK/ERK ; mitogen-activated protein kinases ; GFP ; green fluorescent protein ; YFP ; yellow fluorescent protein ; ATP ; adenosine triphosphate ; UTP ; uridine triphosphate ; PPADS ; pyridoxalphosphate-6-azophenyl-2&prime ; 4&prime ; -disulfonic acid ; Up4U

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

10.Chemerin-induced arterial contraction is G_i- and calcium-dependent

作者：David J. Ferland ; ^{ferlandd@msu.edu} ; Emma S. Darios ; Richard R. Neubig ; Benita Sjö ; gren ; Nguyen Truong ; Rosa Torres ; Thomas S. Dexheimer ; Janice M. Thompson ; Stephanie W. Watts

关键词：Akt ; protein kinase B ; ANG II ; angiotensin II ; CaM ; calmodulin ; CCRL2 ; chemokine (CC motif) receptor-like 2 ; CMKLR1 ; chemokine-like receptor 1 ; Erk MAPK ; extracellular signal-regulated kinase mitogen activated protein kinase ; GAP ; GTPase activating protein ; GEF ; guanine nucleotide exchange factor ; GPR1 ; G protein-coupled receptor 1 ; MLC ; myosin light-chain ; MLCK ; myosin light-chain kinase ; MLCP ; myosin light-chain phosphatase ; PD098059 ; 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one ; PE ; phenyleph

刊名：Vascular Pharmacology

出版年：2017

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