作者：Lucia Longo^a ; Maria Cecilia Mengoli^b ; Federica Bertolini^c ; ^{bertolini.federica@policlinico.mo.it} ; ^{federica.bertolini@tiscali.it} ; Stefania Bettelli^b ; Samantha Manfredini^b ; Giulio Rossi^d

关键词：Lung cancer ; Adenocarcinoma ; Squamous cell carcinoma ; EGFR ; Mutation

刊名：Lung Cancer

出版年：2017

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

作者：Federica Guffanti^* ; ³ ; Rosaria Chilà ; ^* ; ³ ; Ezia Bello^* ; Massimo Zucchetti^&dagger ; ; Monique Zangarini^&dagger ; ; Laura Ceriani^&dagger ; ; Mariella Ferrari^&dagger ; ; Monica Lupi^&dagger ; ; Anne Jacquet-Bescond^&Dagger ; ; Mike F. Burbridge^&Dagger ; ; Marie-Jeanne Pierrat^&Dagger ; ; Giovanna Damia^* ; ^{giovanna.damia@marionegri.it}

刊名：Neoplasia

出版年：2017

作者：Clara Lubeseder-Martellato^a ; ^{clara.lubeseder-martellato@tum.de} ; Katharina Alexandrow^a ; Ana Hidalgo-Sastre^a ; Irina Heid^b ; Sophie Luise Boos^a ; ^c ; Thomas Briel^a ; Roland M. Schmid^a ; ^c ; Jens T. Siveke^a ; ^c ; ^d ; ^{j.siveke@dkfz.de}

关键词：Oncogenic KRas ; Fluid-phase endocytosis ; Pancreatic ductal adenocarcinoma (PDAC) ; Acinar-to-ductal metaplasia (ADM) ; Acinar epithelial explants ; Neural-Wiskott-Aldrich syndrome protein (N-WASP) ; Mice models

刊名：EBioMedicine

出版年：2017

作者：Dandan Li^a ; ¹ ; Lu Zhang^a ; ¹ ; Junhao Zhou^b ; Hong Chen^a ; ^{hopehong2003@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：CSE ; EGFR-TKI resistance ; EMT ; Src ; NSCLC

刊名：Lung Cancer

出版年：2016

作者：Steffen Filskov Sorensen ; MD^a ; ^{stesoe@rm.dk" class="auth_mail" title="E-mail the corresponding author} ; Christina Demuth^b ; Britta Weber^a ; Boe Sandahl Sorensen^b ; Peter Meldgaard^a

关键词：Non-small cell lung cancer ; EGFR mutation ; Soluble PD-1 ; Erlotinib ; Tumor microenvironment

刊名：Lung Cancer

出版年：2016

作者：Lin Zhou^a ; Jiazhuo He^a ; Weijie Xiong^a ; Yongmei Liu^a ; Jing Xiang^b ; Qin Yu^b ; Maozhi Liang^b ; Xiaojuan Zhou^a ; Zhenyu Ding^a ; Meijuan Huang^a ; Li Ren^a ; Jiang Zhu^a ; Lu Li^a ; Mei Hou^a ; Lieming Ding^c ; Fenlai Tan^c ; You Lu^a ; ^{radyoulu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：BBB ; blood-brain barrier ; BCRP ; breast cancer&ndash ; resistant protein ; CIs ; confidence intervals ; CSF ; cerebrospinal fluid ; CT ; computed tomography ; DCR ; disease control rates ; DLT ; dose-limiting toxicity ; ECOG ; Eastern Cooperative Oncology Group ; EC-PFS ; extracranial lesions progression-free survival ; EGFR-TKIs ; epidermal growth factor receptor tyrosine kinase inhibitors ; FACT-L ; functional assessment of cancer therapy-lung scale ; HPLC/MS/MS ; high-performance liquid chromatography/tandem mass s

刊名：Lung Cancer

出版年：2016

作者：Maria Moksnes Bjaanæ ; s^a ; ^b ; ¹ ; ^{mamok@rr-research.no" class="auth_mail" title="E-mail the corresponding author} ; Thomas Fleischer^a ; ^e ; ¹ ; ^{thomas.fleischer@rr-research.no" class="auth_mail" title="E-mail the corresponding author} ; Ann Rita Halvorsen^a ; ^{Ann.Rita.Halvorsen@rr-research.no" class="auth_mail" title="E-mail the corresponding author} ; Antoine Daunay^h ; ^{antoine.daunay@cephb.fr" class="auth_mail" title="E-mail the corresponding author} ; Florence Busato^g ; ^{busato@cng.fr" class="auth_mail" title="E-mail the corresponding author} ; Steinar Solberg^c ; ^{Steinar.Solberg@oslo-universitetssykehus.no" class="auth_mail" title="E-mail the corresponding author} ; Lars Jø ; rgensen^c ; ^{Lars.Jorgensen@oslo-universitetssykehus.no" class="auth_mail" title="E-mail the corresponding author} ; Elin Kure^a ; ^{Elin.Kure@rr-research.no" class="auth_mail" title="E-mail the corresponding author} ; Hege Edvardsen^a ; ² ; ^{hege.edvardsen@abbvie.com" class="auth_mail" title="E-mail the corresponding author} ; Anne-Lise Bø ; rresen-Dale^a ; ^d ; ^{a.l.borresen-dale@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author} ; Odd Terje Brustugun^a ; ^b ; ^{ot.brustugun@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jö ; rg Tost^g ; ^{tost@cng.fr" class="auth_mail" title="E-mail the corresponding author} ; Vessela Kristensen^a ; ^e ; ^f ; ^{v.n.kristensen@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author} ; Å ; slaug Helland^a ; ^b ; ^{aslaug.helland@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：DNA methylation ; Lung cancer ; EGFR ; NSCLC ; LUAD ; TP53 ; mRNA ; Adenocarcinoma ; KRAS ; Prognosis ; CpG ; TP53 ; 450K

刊名：Molecular Oncology

出版年：2016

作者：Corey A. Carter^a ; ^{coreycartermd@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Bryan Oronsky^b ; Scott Caroen^b ; Jan Scicinski^b ; Pedro Cabrales^c ; Aiste Degesys^a ; Christina Brzezniak^a

关键词：NSCLC ; T790 mutation ; EGFR ; RRx-001 ; Episensitization

刊名：Respiratory Medicine Case Reports

出版年：2016