搜索页_+nucleoside+analog+inhibitors

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在“Elsevier电子期刊”中，命中：599条，耗时：0.0269861 秒

在所有数据库中总计命中：834条

1.Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases

作者：Milo&scaron ; Luká ; č^a ; ¹ ; Dana Hocková ; ^a ; Dianne T. Keough^b ; Luke W. Guddat^b ; Zlatko Janeba^a ; ^{janeba@uochb.cas.cz}

关键词：Acyclic nucleoside phosphonates ; 6-oxopurine ; Hypoxanthine-guanine-(xanthine) phosphoribosyltransferase ; Copper(I)-catalyzed azide-alkyne cycloaddition

刊名：Tetrahedron

出版年：2017

2.Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard first-line antiretroviral therapy regimen: a substudy of the randomised, open-label, non-inferiority SEC

作者：Prof Mark A Boyd ; MD^a ; ^b ; ^{mark.boyd@adelaide.edu.au} ; Janaki Amin ; PhD^b ; Patrick W G Mallon ; PhD^c ; Nagalingeswaran Kumarasamy ; MD^d ; Johan Lombaard ; MD^e ; Prof Robin Wood ; PhD^f ; Prof Ploenchan Chetchotisakd ; MD^g ; Prof Praphan Phanuphak ; PhD^h ; Lerato Mohapi ; MDⁱ ; Iskandar Azwa ; MD^j ; Waldo H Belloso ; MD^k ; Prof Jean-Michel Molina ; PhD^l ; Prof Jennifer Hoy ; MD^m ; Cecilia L Moore ; MIPH^b ; Prof Sean Emery ; PhD^b ; Prof David A Cooper ; FAA^b ; on behalf of the SECOND-LINE Study Group^&dagger ;

刊名：The Lancet HIV

出版年：2017

3.New antiviral approaches for respiratory syncytial virus and other mononegaviruses: Inhibiting the RNA polymerase

作者：Rachel Fearns^a ; ^{rfearns@bu.edu" class="auth_mail" title="E-mail the corresponding author} ; Jerome Deval^b ; ^{jdeval@its.jnj.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Respiratory syncytial virus ; Non-segmented negative-strand RNA virus ; RNA-dependent RNA polymerases (RdRps) ; Virus inhibitors ; Nucleoside analog ; Non-nucleoside inhibitor

刊名：Antiviral Research

出版年：2016

4.Simultaneous quantitative determination of 5-aza-2′-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors

作者：Nicole M. Anders^a ; ^b ; ¹ ; Jianyong Liu^a ; ^b ; ¹ ; Teresia Wanjiku^a ; ^b ; Hugh Giovinazzo^c ; Jianya Zhou^a ; ^b ; ^d ; Ajay Vaghasia^a ; ^b ; William G. Nelson^a ; ^b ; ^c ; ^e ; ^f ; Srinivasan Yegnasubramanian^a ; ^b ; ^f ; ^{syegnasu@jhmi.edu" class="auth_mail" title="E-mail the corresponding author} ; Michelle A. Rudek^a ; ^b ; ^g ; ^{mrudek2@jhmi.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：5-Aza-2&prime ; -deoxycytidine ; Decitabine ; DNA methyltransferase inhibitor ; LC/MS/MS ; Genomic DNA ; Global DNA demethylation ; 5-Methyl-2&prime ; -deoxycytidine ; 5-Methylcytosine

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

5.Structural optimization of non-nucleoside DNA methyltransferase inhibitor as anti-cancer agent

作者：Bo Zhong^a ; Sergei Vatolin^b ; Nethrie D. Idippily^a ; Rati Lama^a ; Laila A. Alhadad^a ; Frederic J. Reu^b ; ^{reuf@ccf.org" class="auth_mail" title="E-mail the corresponding author} ; Bin Su^a ; ^c ; ^{B.su@csuohio.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：DNMT1 ; Cancer ; Non-nucleosides ; Drug development

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine

作者：Philip C.T. Tang^a ; Cui Yang^b ; Rachel Wai-Sum Li^a ; Simon Ming-Yuen Lee^c ; Maggie Pui-man Hoi^c ; Shun-Wan Chan^d ; Yiu-Wa Kwan^e ; Chung-Ming Tse^f ; George Pak-Heng Leung^a ; ^{gphleung@hku.hk" class="auth_mail" title="E-mail the corresponding author}

关键词：Cancer ; Cardiovascular disease ; Equilibrative nucleoside transporters ; Inhibitor

刊名：European Journal of Pharmacology

出版年：2016

7.Thiazolo[3,2-a]benzimidazol-3(2H)-one derivatives: Structure-activity relationships of selective nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) inhibitors

作者：Sang-Yong Lee^a ; Arianna Perotti^a ; Steven De Jonghe^b ; Piet Herdewijn^b ; Theodor Hanck^a ; Christa E. Mü ; ller^a ; ^{christa.mueller@uni-bonn.de" class="auth_mail" title="E-mail the corresponding author}

关键词：APs ; alkaline phosphatases ; CE ; capillary electrophoresis ; CHES ; 2-(N-cyclohexylamino)ethanesulfonic acid ; HEPES ; 4-(2-hydroxyethyl)piperazine-1-ethanesulfonic acid ; eN ; ecto-5&prime ; -nucleotidase ; LDC (18 ; 1) ; 1-oleoyl-sn-glycero-3-phosphocholine ; p-Nph-5&prime ; -TMP ; p-nitrophenyl 5&prime ; -thymidine monophosphate ; NPPs ; ecto-nucleotide pyrophosphatases/phosphodiesterases ; NTPDases ; ecto-nucleoside triphosphate diphosphohydrolases ; POM ; polyoxometalate ; SDS ; sodium dodecyl sulfate ; TNAP ; tissue-n

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

8.HIV-1 non-nucleoside reverse transcriptase inhibitors: incorporation of benzylphosphonate moiety for solubility improvement

作者：Elena S. Matyugina^a ; Vladimir T. Valuev-Elliston^a ; Alexander O. Chizhov^b ; Sergei N. Kochetkov^a ; Anastasia L. Khandazhinskaya^a ; ^{khandazhinskaya@bk.ru" class="auth_mail" title="E-mail the corresponding author}

刊名：Mendeleev Communications

出版年：2016

9.Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents

作者：Lijun Song^a ; Martijn D.P. Risseeuw^a ; Matheus Froeyen^b ; Izet Karalic^a ; Jan Goeman^c ; Davie Cappoen^d ; Johan Van der Eycken^c ; Paul Cos^d ; Hé ; lè ; ne Munier-Lehmann^e ; ^f ; Serge Van Calenbergh^a ; ^{serge.vancalenbergh@ugent.be" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV ; human immunodeficiency virus ; LTBI ; latent tuberculosis infection ; MDR-TB ; multidrug-drug resistant tuberculosis ; Mtb ; Mycobacterium tuberculosis ; TMPK ; thymidine monophosphate kinase ; dTMP ; thymidine 5&prime ; -monophosphate ; dTDP ; thymidine 5&prime ; -diphosphate ; dTTP ; thymidine 5&prime ; -triphosphate

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

10.Design and synthesis of novel distamycin-modified nucleoside analogues as HIV-1 reverse transcriptase inhibitors

作者：Chao Li ; Chunying Ma ; Jin Zhang ; Ning Qian ; Jingjing Ding ; Renzhong Qiao ; Yufen Zhao

关键词：Nucleoside analogue ; Anti-HIV ; Antiretrovirals ; Distamycin ; ProTide

刊名：Antiviral Research

出版年：February, 2014

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