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在“Elsevier电子期刊”中，命中：386条，耗时：小于0.01 秒

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1.Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine nucleoside phosphorylase

作者：Giulia Cattaneo^a ; ¹ ; Daniela Ubiali^a ; ^e ; ² ; Enrica Calleri^a ; ² ; Marco Rabuffetti^b ; Georg C. Hö ; fner^c ; Klaus T. Wanner^c ; Marcela C. De Moraes^d ; Leonardo K.B. Martinelli^f ; Dió ; genes Santiago Santos^f ; Giovanna Speranza^b ; ^e ; Gabriella Massolini^a ; ^{gabriella.massolini@unipv.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Mycobacterium tuberculosis purine nucleoside phosphorylase ; Human purine nucleoside phosphorylase ; Enzyme inhibition ; LC-ESI-MS/MS assay ; 96-Well enzymatic assay ; 8-Substituted purine ribonucleosides

刊名：Analytica Chimica Acta

出版年：2016

2.6-Methylpurine derived sugar modified nucleosides: Synthesis and evaluation of their substrate activity with purine nucleoside phosphorylases

作者：Abdalla E.A. Hassan^a ; ^b ; ^{abdallaelsayed@zu.edu.eg" class="auth_mail" title="E-mail the corresponding author} ; Reham A.I. Abou-Elkhair^a ; William B. Parker^a ; ^c ; Paula W. Allan^a ; John A. Secrist III^a

关键词：6-Methylpurine ; 2-Fluoroadenine ; Purine nucleosides ; Vorbrü ; ggen glycosylation ; Purine nucleoside phosphorylase ; Cancer gene therapy

刊名：Bioorganic Chemistry

出版年：2016

3.6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase

作者：Abdalla E.A. Hassan^a ; ^c ; ^{abdallaelsayed@zu.edu.eg" class="auth_mail" title="E-mail the corresponding author} ; Reham A.I. Abou-Elkhair^a ; ^c ; William B. Parker^a ; ^b ; Paula W. Allan^a ; John A. Secrist III^a ;

关键词：6-Methylpurine ; 2-Fluoroadenine ; Purine nucleoside phosphorylase ; Prodrugs ; Cancer gene therapy

刊名：European Journal of Medicinal Chemistry

出版年：2016

4.Development of a capillary electrophoresis method for analyzing adenosine deaminase and purine nucleoside phosphorylase and its application in inhibitor screening

作者：Yanfei Qi ; Youxin Li ; ^{lyx@tju.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; ^{liyouxin2008@163.com" class="auth_mail" title="E-mail the corresponding author} ; James J. Bao

关键词：Capillary electrophoresis ; Adenosine deaminase ; Purine nucleoside phosphorylase ; Inhibitor screening ; Red blood cells ; Traditional Chinese medicines

刊名：Analytical Biochemistry

出版年：2016

5.Development of a new HPLC method using fluorescence detection without derivatization for determining purine nucleoside phosphorylase activity in human plasma

关键词：PNP ; purine nucleoside phosphorylase ; Pi ; inorganic phosphate ; INO ; inosine ; GUO ; guanosine ; UA ; uric acid ; HYPO ; hypoxanthine ; GUA ; guanine ; XAN ; xanthine ; NaOH ; sodium hydroxide ; K2HPO4 ; dipotassium phosphate ; KH2PO4 ; monopotassium phosphate ; HEPES ; 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid ; DAD ; diode array detector ; PFP ; pentafluorophenyl ; QC ; quality control ; LOD ; limit of detection ; LOQ ; limit of quantification ; r ; correlation coefficient

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

6.A continuous spectrophotometric enzyme-coupled assay for deoxynucleoside triphosphate triphosphohydrolases

作者：Deepa Singh^a ; Roel M. Schaaper^a ; Alejandro Hochkoeppler^b ; ^c ; ^{a.hochkoeppler@unibo.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Enzyme-coupled assay ; Deoxynucleoside triphosphatase ; Escherichia coli Dgt ; Purine nucleoside phosphorylase ; Xanthine oxidase ; 8-Oxoguanine

刊名：Analytical Biochemistry

出版年：2016

7.Complex coordinated extracellular metabolism: Acid phosphatases activate diluted human leukocyte proteins to generate energy flow as NADPH from purine nucleotide ribose

作者：John B. Hibbs Jr.^a ; ^b ; ^{john.hibbs@hsc.utah.edu" class="auth_mail" title="E-mail the corresponding author} ; Zdenek Vavrin^b ; James E. Cox^c ; ^d

关键词：AUC ; area under the curve ; FGT ; female genital tract ; GC&ndash ; MS ; gas chromatography-mass spectrometry ; GSH ; reduced glutathione ; GSSG ; oxidized glutathione ; LC&ndash ; MS ; liquid chromatography&ndash ; mass spectrometry ; NET ; neutrophil extracellular trap ; NO ; nitric oxide ; NOB-PPP ; non-oxidative branch pentose phosphate pathway ; OB-PPP ; oxidative branch pentose phosphate pathway ; Pi ; inorganic phosphate ; PAP ; human prostate acid phosphatase ; PNP ; purine nucleoside phosphorylase ; PNCP ; purine nucl

刊名：Redox Biology

出版年：2016

8.Enzymatic synthesis and RNA interference of nucleosides incorporating stable isotopes into a base moiety

作者：Akihiko Hatano^a ; ^{a-hatano@sic.shibaura-it.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Mitsuya Shiraishi^b ; Nanae Terado^a ; Atsuhiro Tanabe^a ; Kenji Fukuda^c

关键词：Thymidine phosphorylase ; Nucleoside synthesis ; Nucleosides incorporating stable isotopes ; 13C NMR ; RNA interference

刊名：Bioorganic & Medicinal Chemistry

出版年：2015

9.A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritima

作者：Hanan M.A. Moustafa^a ; ^b ; Taha I. Zaghloul^b ; Y.-H. Percival Zhang^a ; ^c ; ^{ypzhang@vt.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Biocatalysis ; Enzymatic assay ; Phosphopentomutase ; Thermophilic enzyme ; Thermotoga maritima

刊名：Analytical Biochemistry

出版年：2016

10.Purine metabolism in response to hypoxic conditions associated with breath-hold diving and exercise in erythrocytes and plasma from bottlenose dolphins (Tursiops truncatus)

作者：Iris del Castillo Velasco-Martí ; nez^a ; ^{idelcastillo@pg.cibnor.mx" class="auth_mail" title="E-mail the corresponding author} ; Claudia J. Herná ; ndez-Camacho^b ; ^{cjhernandez78@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Lí ; a C. Mé ; ndez-Rodrí ; guez^a ; ^{lmendez04@cibnor.mx" class="auth_mail" title="E-mail the corresponding author} ; Tania Zenteno-Saví ; n^a ; ^{tzenteno04@cibnor.mx" class="auth_mail" title="E-mail the corresponding author}

关键词：Breath-hold diving ; Bottlenose dolphin ; Erythrocytes ; Exercise ; Hypoxia ; Purine metabolism ; Purine salvage

刊名：Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology

出版年：2016

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