搜索页_ peroxisome proliferator-activated receptor-γ coactivator 1α

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1.Concerted action of histone methyltransferases G9a and PRMT-1 regulates PGC-1α-RIG-I axis in IFNγ treated glioma cells

作者：Ruchi Ghildiyal ; Ellora Sen ; ^{ellora@nbrc.ac.in}

关键词：IFNγ ; interferon gamma ; RIG-I ; retinoic acid (RA)-inducible gene-I ; SFM ; serum free media ; ChIP ; chromatin immunoprecipitation ; NFκB ; nuclear factor kappa B ; PGC-1α ; peroxisome proliferator-activated receptor gamma coactivator-1 alpha ; PRMT-1 ; protein arginine methyltransferase 1 ; MTS ; 3-(4 ; 5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium ; TUNEL ; terminal deoxynucleotidyl transferase dUTP nick end labeling

刊名：Cytokine

出版年：2017

2.Estrogen Signals Through Peroxisome Proliferator-Activated Receptor−γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease

作者：Aurè ; le Besse-Patin¹ ; ² ; Mé ; lissa Lé ; veillé ; ¹ ; ² ; Daniel Oropeza¹ ; ³ ; Bich N. Nguyen⁴ ; ⁵ ; Annik Prat⁶ ; Jennifer L. Estall¹ ; ² ; ³ ; ^{jennifer.estall@ircm.qc.ca}

关键词：NASH ; PGC-1 ; ROS ; PGC1B

刊名：Gastroenterology

出版年：2017

3.Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase inhibitors in neurons: Potential contribution to HIV-associated neurocognitive disorders

作者：Kui-Ming Hung^a ; ^b ; Pei-Chun Chen^b ; Han-Chieh Hsieh^c ; Marcus J Calkins^a ; ^{mjcalkins@mail.ncku.edu.tw}

关键词：NRTI ; nucleoside/nucleotide reverse transcriptase inhibitor ; HAND ; HIV-associated neurocognitive disorders ; cART ; combination antiretroviral therapy ; pol γ ; polymerase γ ; mtDNA ; mitochondrial DNA ; ddI ; didanosine ; AZT ; zidovudine ; FTC ; emtricitabine ; TDF ; tenofovir ; ddC ; zalcitabine ; d4T ; stavudine ; 3TC ; lamivudine ; ABC ; abacavir ; PGC-1α ; peroxisome proliferator-activated receptor γ coactivator 1α ; mtUPR ; mitochondrial unfolded protein response ; CO1 ; Cytochrome oxidase I ; ND1 ; NADH Dehydrogenase

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

4.Effect of novel dietary supplement on metabolism in vitro and in vivo

作者：Roger A. Vaughan^a ; ^b ; ^c ; ^d ; ^{roger.vaughan@ttu.edu} ; ^{vaughanr@unm.edu} ; Ailish C. White^b ; Jason R. Beam^b ; Nicholas P. Gannon^c ; Randi Garcia-Smith^c ; Roy M. Salgado^b ; Marco Bisoffi^c ; ^e ; ^f ; Kristina A. Trujillo^c ; ^e ; Carole A. Conn^d ; Christine M. Mermier^b

关键词：Obesity ; Thermogenic agent ; Fat burner ; Resting energy expenditure ; Mitochondrial biogenesis ; Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)

刊名：Journal of Traditional and Complementary Medicine

出版年：2017

5.Ginger extract increases muscle mitochondrial biogenesis and serum HDL-cholesterol level in high-fat diet-fed rats

作者：Soojung Oh^a ; ¹ ; Mak-Soon Lee^a ; ¹ ; Sunyoon Jung^a ; ¹ ; Seunghae Kim^a ; Hyeyoung Park^a ; Seonyoung Park^a ; Seog-Young Kim^a ; Chong-Tai Kim^b ; Young-Hee Jo^b ; In-Hwan Kim^c ; Yangha Kim^a ; ^{yhmoon@ewha.ac.kr}

关键词：ABCA1 ; ATP-binding cassette transporter A1 ; ApoA-1 ; apolipoprotein A-1 ; CYP7A1 ; 7 alpha-hydroxylase ; GEH ; high-fat diet containing 0.5% ginger extract ; GEL ; high-fat diet containing 0.25% ginger extract ; HDL-C ; high-density lipoprotein-cholesterol ; HF ; high-fat diet ; LCAT ; lecithin-cholesterol acyltransferase ; LDL-C ; low-density lipoprotein-cholesterol ; mtDNA ; mitochondrial DNA ; NRF ; nuclear respiratory factor ; PGC-1α ; peroxisome proliferator-activated receptor γ coactivator-1α ; PPAR ; peroxisome

刊名：Journal of Functional Foods

出版年：2017

6.PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease

作者：Juan Carlos Corona^a ; ^b ; Michael R. Duchen^a ; ^{m.duchen@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：PPARγ ; peroxisome proliferation-activated receptor gamma ; 15D-PGJ2 ; 15-deoxy-Δ12 ; 14-Prostaglandin J2 ; TZDs ; thiazolidinediones ; CNS ; central nervous system ; WAT ; white adipose tissue ; BAT ; brown adipose tissue ; SRC ; steroid receptor coactivator ; CBP ; CREB-binding protein ; AF-1 ; transcriptional activation domain ; PGC1α ; peroxisome proliferator-activated receptor gamma coactivator 1α ; TFAM ; mitochondrial transcription factor A ; mtDNA ; mitochondrial DNA ; UCP-1 ; uncoupling protein 1 ; UCP-2 ; uncoupli

刊名：Free Radical Biology and Medicine

出版年：2016

7.Upregulation of MKP-7 in response to rosiglitazone treatment ameliorates lipopolysaccharide-induced destabilization of SIRT1 by inactivating JNK

作者：Jung Seok Hwang^a ; Sun Ah Ham^a ; Taesik Yoo^a ; Won Jin Lee^a ; Kyung Shin Paek^b ; Jae-Hwan Kim^c ; Chi-Ho Lee^a ; Han Geuk Seo^a ; ^{hgseo@konkuk.ac.kr}

关键词：SIRT1 ; silent mating type information regulation 2 homolog 1 ; PPARγ ; peroxisome proliferator-activated receptor γ ; LPS ; lipopolysaccharide ; MKP-7 ; mitogen-activated protein kinase phosphatase-7 ; PGC-1α ; peroxisome proliferator-activated receptor gamma coactivator-1α ; NF-κB ; nuclear factor kappa B ; AP-1 ; activator protein-1 ; HMGB1 ; high mobility group box 1 ; JNK1 ; c-Jun N-terminal kinase 1 ; MDM2 ; mouse double minute 2 homolog ; USP-22 ; ubiquitin-specific protease-22 ; PPRE ; PPAR-response element ; S

刊名：Pharmacological Research

出版年：2016

8.Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of duchenne muscular dystrophy: A comparison with the gold standard, α-methyl prednisolone

作者：Roberta Francesca Capogrosso^a ; ^d ; ¹ ; Anna Cozzoli^a ; ¹ ; Paola Mantuano^a ; Giulia Maria Camerino^a ; Ada Maria Massari^a ; Valeriana Teresa Sblendorio^a ; Michela De Bellis^a ; Roberto Tamma^c ; Arcangela Giustino^b ; Beatrice Nico^c ; Monica Montagnani^b ; Annamaria De Luca^a ; ^{annamaria.deluca@uniba.it" class="auth_mail" title="E-mail the corresponding author}

关键词：DMD ; Duchenne muscular dystrophy ; EDL ; extensor digitorum longus muscle ; TA ; tibialis anterior muscle ; GC ; gastrocnemius muscle ; SIRT1 ; NAD-dependent histone deacetylase sirtuin 1 ; PGC-1α ; peroxisome proliferator-activated receptor γ coactivator-1α ; PPAR ; peroxisome proliferator-activated receptors ; Src-TK ; Src tirosine-kinase ; NOX ; NADPH oxidase ; ROS ; reactive oxygen species ; PDN ; α-methyl prednisolone ; gm ; resting sarcolemma ionic conductance ; gCl ; resting conductance to chloride ion ; MT ; mech

刊名：Pharmacological Research

出版年：2016

9.CTRP3 promotes energy production by inducing mitochondrial ROS and up-expression of PGC-1α in vascular smooth muscle cells

作者：Han Feng^a ; ^b ; ^c ; Jin-Yu Wang^a ; ^b ; ^c ; Ming Zheng^a ; ^b ; ^c ; Cheng-Lin Zhang^a ; ^b ; ^c ; Yuan-Ming An^a ; ^b ; ^c ; Li Li^a ; ^b ; ^c ; ^{lilyby@163.com" class="auth_mail" title="E-mail the corresponding author} ; Li-Ling Wu^a ; ^b ; ^c ; ^{pathophy@bjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：CTRP3 ; Energy metabolism ; Oxidative phosphorylation ; Mitochondrial reactive oxygen species ; Peroxisome proliferator-activated receptor γ co-activator 1-α ; Vascular smooth muscle cell

刊名：Experimental Cell Research

出版年：2016

10.Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients

作者：Thomas Trian ; PhD^a ; ^b ; ^{thomas.trian@u-bordeaux.fr" class="auth_mail" title="E-mail the corresponding author} ; Benoit Allard ; PhD^a ; ^b ; Annaig Ozier ; MD ; PhD^a ; ^b ; ^c ; Elise Maurat^a ; ^b ; Isabelle Dupin ; PhD^a ; ^b ; Matthieu Thumerel ; MD^a ; ^b ; ^c ; Olga Ousova ; PhD^a ; ^b ; Jennifer Gillibert-Duplantier ; PhD^a ; ^b ; Valé ; rie Le Morvan ; PhD^d ; Hugues Begueret ; MD ; PhD^c ; Pierre-Olivier Girodet ; MD ; PhD^a ; ^b ; ^c ; Roger Marthan ; MD ; PhD^a ; ^b ; ^c ; Patrick Berger ; MD ; PhD^a ; ^b ; ^c

关键词：Asthma ; remodeling ; lentivirus ; peroxisome proliferator-activated receptor γ coactivator 1α ; mitochondrial transcription factor A

刊名：Journal of Allergy and Clinical Immunology

出版年：2016

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