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在“Elsevier电子期刊”中，命中：780条，耗时：0.0389792 秒

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1.Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer

作者：Atsushi Nakamura ; ^{atsushi_nakamura@shionogi.co.jp} ; Hiroko Ono ; Azusa Ando ; Mikie Hinata ; Kazuki Niidome ; Shigeki Omachi ; Gaku Sakaguchi ; Shunji Shinohara

关键词：Antinociception ; Bone cancer pain ; Extracellular regulated kinase ; Opioid ; Rewarding effect

刊名：Journal of Pharmacological Sciences

出版年：2017

2.5-HT₇ receptor-mediated fear conditioning and possible involvement of extracellular signal-regulated kinase

作者：Kotaro Takeda ; Minoru Tsuji ; ^{mtsuji@iuhw.ac.jp} ; Kazuya Miyagawa ; Hiroshi Takeda

关键词：5-HT ; serotonin ; DR4004 ; 2a-[4-(4-phenyl-123 ; 6-tetrahydropyridyl)butyl]-2a34 ; -tetrahydrobenzo(c ; d)indol-2-(1H)-one ; ERK ; extracellular signal-regulated kinase 1/2 ; pERK ; phosphorylated ERK ; CS ; conditioned stimulus ; US ; unconditioned stimulus ; mRNA ; messenger RNA ; i.p. ; intraperitoneally ; ANOVA ; analysis of variance ; TrkB ; tropomyosin-related kinase B ; BDNF ; brain-derived neurotrophic factor

刊名：Neuroscience Letters

出版年：2017

3.Analgesic effect of coumarins from Radix angelicae pubescentis is mediated by inflammatory factors and TRPV1 in a spared nerve injury model of neuropathic pain

作者：Ruili Li^a ; ¹ ; Chao Zhao^a ; ¹ ; Minna Yao^a ; Ying Song^b ; Yin Wu^a ; ; Aidong Wen^a ; ^{lwrcll@163.com}

关键词：CRAP ; Coumarins from Radix angelicae pubescentis ; SNI ; spared nerve injury ; DRG ; dorsal root ganglion ; CRAP ; coumarins from Radix angelicae pubescentis ; IL-1β ; interleukin-1β ; IL-6 ; interleukin-6 ; TNF-α ; tumor necrosis factor-α ; TRPV1 ; Transient receptor potential cation channel 1 ; pERK ; Phosphorylated extracellular regulated protein kinases ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinases ; LOD ; limit of detection ; LOQ ; limit of quantification ; ELISA ; Enzyme-linked immunosorbent

刊名：Journal of Ethnopharmacology

出版年：2017

4.A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents

作者：Isabel Leung¹ ; ² ; Nick Jarvik² ; Sachdev S. Sidhu¹ ; ² ; ^{sachdev.sidhu@utoronto.ca}

关键词：Ubv ; ubiquitin variant ; Ub ; ubiquitin ; wt ; wild-type ; EGFR ; epidermal growth factor receptor ; EGF ; epidermal growth factor ; Her3 ; human epidermal growth factor receptor 3 ; NRG ; neuregulin ; Grb2 ; growth factor receptor-bound protein 2 ; GST ; glutathione S-transferase ; SPR ; surface plasmon resonance ; IP ; immunoprecipitation ; Grb2-SH2 ; Grb2 SH2 domain ; p-Tyr ; phospho-tyrosine ; pERK ; phosphorylated ERK ; pMEK ; phosphorylated MEK ; ERK ; extracellular signal-regulated kinase ; MEK ; MAPK/ERK kinase

刊名：Journal of Molecular Biology

出版年：2017

5.Regulation of Siglec-8-induced intracellular reactive oxygen species production and eosinophil cell death by Src family kinases

作者：Gen Kano^a ; ^b ; Bruce S. Bochner^c ; Nives Zimmermann^a ; ^d ; ^{nives.zimmermann@cchmc.org}

关键词：Eosinophils ; Cell death

刊名：Immunobiology

出版年：2017

6.Statins inhibited the MIP-1α expression via inhibition of Ras/ERK and Ras/Akt pathways in myeloma cells

作者：Masanobu Tsubaki^a ; Kenji Mashimo^a ; ^b ; Tomoya Takeda^a ; Toshiki Kino^a ; Arisa Fujita^a ; Tatsuki Itoh^c ; Motohiro Imano^d ; Katsuhiko Sakaguchi^b ; Takao Satou^e ; Shozo Nishida^a ; ^{nishida@phar.kindai.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：DMSO ; dimethyl sulfoxide ; HMG-CoA ; 3-hydroxy-3-methylglutaryl-coenzyme A ; ERK1/2 ; extracellular signal-regulated kinase 1/2 ; FPP ; farnesyl pyrophosphate ; GGPP ; geranylgeranyl pyrophosphate ; LPS ; lipopolysaccharide ; MIP-1α ; macrophage inflammatory protein-1alpha ; MVA ; mevalonic acid ; MAPK ; mitogen-activated protein kinase ; MM ; multiple myeloma ; PBMC ; speripheral blood mononuclear cells ; PBS ; phosphate buffered saline ; TLRs ; toll-like receptors ; TNF-α ; tumor necrosis factor α

刊名：Biomedicine & Pharmacotherapy

出版年：2016

7.Localization of active, dually phosphorylated extracellular signal-regulated kinase 1 and 2 in colorectal cancer with or without activating BRAF and KRAS mutations

作者：Susanne Holck ; MD ; DMSc^a ; Jesper Bonde ; PhD^a ; ^b ; Helle Pedersen ; BA^a ; Anja Alex Petersen ; BA^a ; ^b ; Amita Chaube ; PhD^a ; Hans Jø ; rgen Nielsen ; MD ; DMSc^c ; Lars-Inge Larsson ; MD ; DSc^a ; ^b ; ^{lars.inge.larsson@regionh.dk" class="auth_mail" title="E-mail the corresponding author}

关键词：ERK ; KRAS ; BRAF ; Mutations ; Colorectal carcinoma ; Immunohistochemistry

刊名：Human Pathology

出版年：2016

8.Loss of G_sα impairs liver regeneration through a defect in the crosstalk between cAMP and growth factor signaling

作者：Changli Lu¹ ; ² ; ^&dagger ; ; Jie Xia¹ ; ^&dagger ; ; Yongjie Zhou¹ ; ³ ; Xufeng Lu¹ ; Lei Zhang¹ ; ³ ; Maling Gou⁴ ; Lei Li⁵ ; Xiaoyun Zhang⁵ ; Hongjie Ji¹ ; ³ ; Keting Zhu¹ ; ³ ; Li Li¹ ; Jie Zhang¹ ; Ping Yu⁶ ; Jiayin Yang⁵ ; Hong Bu¹ ; ² ; ^{hongbu@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yujun Shi¹ ; ³ ; ^{shiyujun@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：cAMP ; cyclic adenosine monophosphate ; CCl4 ; carbon tetrachloride ; CDK ; cyclin-dependent kinase ; CREB ; cAMP-responsive element-binding protein ; Erk ; extracellular signal-regulated kinase ; GPCR ; G-protein-coupled receptor ; Gsα ; the stimulatory G protein α subunit ; JNK ; c-Jun N-terminal kinases ; MAPK ; mitogen-activated protein kinases ; PH ; partial hepatectomy ; PKA ; protein kinase A ; Rb ; retinoblastoma protein

刊名：Journal of Hepatology

出版年：2016

9.14-3-3η is a novel growth-promoting and angiogenic factor in hepatocellular carcinoma

作者：Jian Shen¹ ; ^&dagger ; ; Fei Jiang² ; ^&dagger ; ; Ye Yang² ; ^&dagger ; ; Guangming Huang³ ; ^&dagger ; ; Fuxing Pu³ ; ^&dagger ; ; Qinqiang Liu¹ ; ^&dagger ; ; Lijun Chen² ; Liang Ju¹ ; Ming Lu¹ ; Fei Zhou¹ ; Chi Zhang¹ ; Xiagang Luo¹ ; Xiaojun Yang¹ ; Chengyu Jiao⁴ ; Xiangcheng Li⁴ ; Zhong Li² ; Yuan Li² ; ^{liyuan@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jianping Zhang¹ ; ^{zjpnjmu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Cxcl1 ; C-X-C motif-ligand 1 ; ECs ; endothelial cells ; EMT ; epithelial to mesenchymal transition ; ERK ; extracellular signal-regulated kinase ; FAK ; focal adhesion kinase ; FRA-1 ; fos related antigen 1 ; NK-κB ; nuclear factor kappa B ; PCNA ; proliferating cell nuclear antigen ; TGF-β ; transforming growth factor beta ; TUNEL ; transferase-mediated deoxyuridine triphosphate-biotin nick end labeling ; VEGF ; vascular endothelial growth factor ; Zeb-1 ; zinc finger E-box-binding protein-1

刊名：Journal of Hepatology

出版年：2016

10.Xinmailong mitigated epirubicin-induced cardiotoxicity via inhibiting autophagy

作者：Hui Li^a ; Yiqing Mao^a ; Qun Zhang^a ; Qing Han^a ; Zhenming Man^a ; Jingyu Zhang^a ; Xi Wang^a ; Ruobi Hu^a ; Xuehui Zhang^a ; David M. Irwin^c ; ¹ ; ^{david.irwin@utoronto.ca" class="auth_mail" title="E-mail the corresponding author} ; Gang Niu^b ; ¹ ; ^{nngene@sohu.com" class="auth_mail" title="E-mail the corresponding author} ; Huanran Tan^a ; ¹ ; ^{tanlab@bjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：ACE ; angiotensin-converting enzyme ; ACE2 ; angiotensin-converting enzyme 2 ; Ang ; angiotensin ; AT1 ; type-1A angiotensin II receptor ; Atg7 ; autophagy related 7 ; Bax ; Bcl-2 associated X protein ; Bcl2 ; B cell lymphoma2 ; CHF ; congestive heart failure ; DOX ; Doxorubicin ; ECG ; surface electrocardiographic recordings ; EF ; ejection fraction ; EPI ; epirubicin ; Erk1/2 ; extracellular regulated protein kinases 1/2 ; FS ; fraction of shortening ; HPLC ; high performance liquid chromatography ; LV Vols ; left ventricl

刊名：Journal of Ethnopharmacology

出版年：2016

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