搜索页_ pregnane X receptor (NR1I2)

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Elsevier电子期刊(26)

在“Elsevier电子期刊”中，命中：26条，耗时：0.0309566 秒

在所有数据库中总计命中：34条

1.Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes

作者：Benjamin A. Kandel^a ; ^b ; Maria Thomas^a ; ^b ; Stefan Winter^a ; ^b ; Georg Damm^c ; Daniel Seehofer^c ; Oliver Burk^a ; ^b ; Matthias Schwab^a ; ^b ; ^d ; Ulrich M. Zanger^a ; ^b ; ^{uli.zanger@ikp-stuttgart.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ADME ; absorption ; distribution ; metabolism ; excretion ; CAR ; constitutive androstane receptor (NR1I3) ; CITCO ; 6-(4-Chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde O-(3 ; 4-dichlorobenzyl)oxime ; CYP ; cytochrome P450 ; DMET ; drug metabolism and transport ; PHH ; primary human hepatocytes ; PPARα ; peroxisome proliferator-activated receptor alpha (NR1C1) ; PXR ; pregnane X receptor (NR1I2) ; WY14 ; 643 ; [[4-chloro-6-[(2 ; 3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

2.Tunicate pregnane X receptor (PXR) orthologs: Transcript characterization and natural variation

作者：Ingrid Richter^a ; ^b ; ^{Ingrid.Richter@cawthron.org.nz" class="auth_mail" title="E-mail the corresponding author} ; Andrew E. Fidler^a ; ^c ; ^d

关键词：AF-1 ; transcription activation function 1 ; AR ; androgen receptor ; BsVDR/PXR伪 ; Botryllus schlosseri VDR/PXR ortholog 伪 ; BSA ; bovine serum albumin ; bp ; base pair ; CAR ; constitutive androstane receptor ; CiVDR/PXR伪 ; Ciona intestinalis VDR/PXR ortholog 伪 ; CiVDR/PXR尾 ; Ciona intestinalis VDR/PXR ortholog 尾 ; DBD ; DNA-binding domain ; dN/dS ; ratio of non-synonymous substitutions per non-synonymous site (dN) to synonymous substitutions per synonymous site (dS) ; ER ; estrogen receptor ; FXR ; farnesoid X recep

刊名：Marine Genomics

出版年：2015

3.3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease

作者：Aik Jiang Lau ; Thomas K.H. Chang ; ^{thomas.chang@ubc.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：3-Hydroxyflavone (PubChem CID ; 11349) ; Galangin (PubChem CID ; 5281616) ; Datiscetin (PubChem CID ; 5281610) ; Kaempferol (PubChem CID ; 5280863) ; Morin (PubChem CID ; 5281670) ; Quercetin dihydrate (PubChem CID ; 5284452) ; Isorhamnetin (PubChem CID ; 5281654) ; Tamarixetin (PubChem CID ; 5281699) ; Myricetin (PubChem CID ; 5281672) ; Syringetin (PubChem CID ; 5281953)

刊名：Pharmacological Research

出版年：2015

4.Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio)

作者：Afonso C.D. Bainy ; Akira Kubota ; Jared V. Goldstone ; Roger Lille-Lang酶y ; Sibel I. Karchner ; Malin C. Cel ; er ; Mark E. Hahn ; Anders Goks酶yr ; John J. Stegeman

关键词：ABC transporters ; ATP-binding cassette transporters ; ARNT2 ; aryl hydrocarbon receptor nuclear translocator ; CAR ; constitutive androstane receptor ; CLO ; clotrimazole ; CYP ; cytochrome P450 ; DBD ; DNA binding domain ; DMSO ; dimethylsulfoxide ; EF1伪 ; elongation factor 1伪 ; LBD ; ligand binding domain ; NIF ; nifedipine ; NR ; nuclear receptor ; PB ; phenobarbital ; PCN ; pregnenolone 16伪-carbonitrile ; PXR ; pregnane X receptor ; RACE ; rapid amplification of cDNA ends ; RIF ; rifampicin ; RXR ; retinoid X-receptor

刊名：Aquatic Toxicology

出版年：15 October, 2013

5.Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo

作者：Emma Jane Poulton^a ; ^b ; Lisa Levy^c ; Johanna W. Lampe^a ; ^c ; Danny D. Shen^a ; ^e ; Julia Tracy^a ; ^b ; Margaret C. Shuhart^d ; Kenneth E. Thummel^a ; ^e ; David L. Eaton^a ; ^b ; ^e ; ^{deaton@uw.edu}

关键词：Sulforaphane ; Cytochrome P450 ; CYP3A4 ; Midazolam ; Pregnane X-receptor ; NR1I2 ; Phase I clinical trial ; Humanized PXR mice ; Isolated hepatocytes

刊名：Toxicology and Applied Pharmacology

出版年：2013

6.Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1

作者：Tingting Zhou^a ; ¹ ; Shuyan Cong^b ; ¹ ; Shiying Sun^a ; Hongmiao Sun^a ; Renlong Zou^a ; Shengli Wang^a ; Chunyu Wang^a ; Jiao Jiao^a ; Kiminobu Goto^c ; Hajime Nawata^d ; Toshihiko Yanase^e ; Yue Zhao^a ; ^{zhaoyue@mail.cmu.edu.cn}

关键词：EDCs ; endocrine disrupting chemicals/environmental endocrine disrupters ; SXR ; steroid xenobiotic receptor in human ; PXR ; pregnane X receptor in rodent (rodent homologue of SXR) ; PAR ; pregnane activated receptor ; LXR¦Á ; liver X receptor alpha ; FXR ; farneso

刊名：Molecular and Cellular Endocrinology

出版年：2013

7.FXR signaling in the enterohepatic system

作者：Tsutomu Matsubara¹ ; Fei Li¹ ; Frank J. Gonzalez ; ^{gonzalef@mail.nih.gov}

关键词：Nuclear receptors ; Farnesoid X receptor ; Bile acids ; Cholestasis ; Liver disease ; Enterohepatic circulation

刊名：Molecular and Cellular Endocrinology

出版年：2013

8.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

作者：Yakun Chen ; Yong Tang ; Changxiong Guo ; Jiuhui Wang ; Debasish Boral ; Daotai Nie ; ^{dnie@siumed.edu} ; ^{labnie@gmail.com}

关键词：ABC ; ATP binding cassette ; AF ; activation function ; AhR ; aryl hydrocarbon receptor ; AHRE ; AhR element ; AIP ; aryl hydrocarbon receptor-interacting protein ; AKRs ; aldo&ndash ; keto reductases ; ARE ; antioxidant response element ; ARNT ; aryl hydrocarbon receptor

刊名：Biochemical Pharmacology

出版年：2012

9.Post-translational modification of pregnane x receptor

作者：Jeff L. Staudinger^a ; ^{stauding@ku.edu"" rel=""nofollow} ; Chenshu Xu^a ; Arunima Biswas^b ; Sridhar Mani^b

关键词：Pregnane x receptor ; Post-translational modification

刊名：Pharmacological Research

出版年：2011

10.Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice

作者：Young Joo Park ; Eun Kyung Lee ; Yoon Kwang Lee ; Do Joon Park ; Hak Chul Jang ; David D. Moore

关键词：CAR ; constitutive androstane receptor ; PXR ; pregnane X receptor ; PTU ; propylthiouracil ; WT ; wild type ; CYP ; cytochrome P450 ; ND ; normal diet ; PTU/LI ; propylthiouracil/low iodine ; T4 ; tetraiodothyronine ; CBZ ; carbamazepine ; MEM ; minimal essential medium ; W

刊名：Toxicology and Applied Pharmacology

出版年：2012

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