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Elsevier电子期刊(116)

在“Elsevier电子期刊”中，命中：116条，耗时：0.0449879 秒

在所有数据库中总计命中：137条

1.Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction

作者：Saurabh G. Vispute^a ; Pengli Bu^a ; ^b ; Yuan Le^a ; Xingguo Cheng^a ; ^{chengx@stjohns.edu}

关键词：APAP ; acetaminophen ; bp ; base pair ; ChIP ; chromatin immunoprecipitation ; Cyp ; cytochrome p450 enzyme ; DEX ; dexamethasone ; Fgf21 ; fibroblast growth factor 21 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid receptor response element ; GSH ; Glutathione ; i.p. ; intraperitoneal ; NAPQI ; N-acetyl-p-benzoquinone imine ; PGC1α ; peroxisome proliferator-activated receptor gamma coactivator protein-1α ; PPAR ; peroxisome proliferator-activated receptor ; PXR ; pregnane X receptor ; TSS ; transcription start site

刊名：Toxicology

出版年：2017

2.Radioligand binding assay for accurate determination of nuclear retinoid X receptors: A case of triorganotin endocrine disrupting ligands

作者：Lucia Toporova ; Dana Macejova ; Julius Brtko ; ^{julius.brtko@savba.sk" class="auth_mail" title="E-mail the corresponding author}

关键词：ATRA ; all-trans retinoic acid ; Bmax ; maximal binding capacity (pmol/mg) ; DNA ; deoxyribonucleic acid ; DR ; direct repeat ; DTT ; 1 ; 4-dithiothreitol ; FXR ; farnesoid X receptor ; Ka ; affinity (l/mol) ; LBD ; ligand-binding domain ; LXR ; liver X receptor ; PMSF ; phenylmethylsulfonyl fluoride ; PPAR ; peroxisome proliferator activated receptor ; PXR ; pregnane X receptor ; RAR ; retinoid receptor ; RARE ; retinoid response element ; RXR ; retinoid X receptor (rexinoid receptor) ; RXRE ; retinoid X response element ; TBT-

刊名：Toxicology Letters

出版年：2016

3.New brominated flame retardants and their metabolites as activators of the pregnane X receptor

作者：Darja Gramec Skledar^a ; Tihomir Toma&scaron ; ič^a ; Adriana Carino^b ; Eleonora Distrutti^b ; Stefano Fiorucci^b ; Lucija Peterlin Ma&scaron ; ič^a ; ^{lucija.peterlin@ffa.uni-lj.si" class="auth_mail" title="E-mail the corresponding author}

关键词：CYP ; cytochrome P450 ; PCR ; polymerase chain reaction ; PPAR ; peroxisome proliferator activated receptor ; PXR ; pregnane X receptor ; TBB ; 2-ethylhexyl 234 ; 5-tetrabromobenzoate ; TBPH ; bis(2-ethylhexyl) tetrabromophthalate ; TBBA ; 234 ; 5-tetrabromobenzoic acid ; TBMEPH ; 2-ethylhexyl tetrabromobenzoate ester

刊名：Toxicology Letters

出版年：2016

4.Mixed-ligand copper(II) complexes activate aryl hydrocarbon receptor AhR and induce CYP1A genes expression in human hepatocytes and human cell lines

作者：Kateřina Kube&scaron ; ová ; ^a ; Aneta Dořičá ; ková ; ^a ; Zdeněk Trá ; vní ; ček^b ; Zdeněk Dvořá ; k^a ; ^{moulin@email.cz" class="auth_mail" title="E-mail the corresponding author}

关键词：AhR ; aryl hydrocarbon receptor ; AR ; androgen receptor ; CYP ; cytochrome P450 ; DEX ; dexamethasone ; DHT ; dihydrotestosterone ; DMF ; N ; N dimethylformamide ; GR ; glucocorticoid receptor ; PXR ; pregnane X receptor ; RIF ; rifampicin ; RVT ; resveratrol ; T3 ; 3 ; 3&prime ; 5-triiodo-l-thyronine ; RXRs ; retinoid X receptors ; TAT ; tyrosine aminotransferase ; TCDD ; 237 ; 8-tetrachlorodibenzo-p-dioxin ; TR ; thyroid hormone receptor ; VD3 ; 25-hydroxyvitamin D3 ; VDR ; vitamin D receptor

刊名：Toxicology Letters

出版年：2016

5.Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes

作者：Benjamin A. Kandel^a ; ^b ; Maria Thomas^a ; ^b ; Stefan Winter^a ; ^b ; Georg Damm^c ; Daniel Seehofer^c ; Oliver Burk^a ; ^b ; Matthias Schwab^a ; ^b ; ^d ; Ulrich M. Zanger^a ; ^b ; ^{uli.zanger@ikp-stuttgart.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ADME ; absorption ; distribution ; metabolism ; excretion ; CAR ; constitutive androstane receptor (NR1I3) ; CITCO ; 6-(4-Chlorophenyl)imidazo[2 ; 1-b][1 ; 3]thiazole-5-carbaldehyde O-(3 ; 4-dichlorobenzyl)oxime ; CYP ; cytochrome P450 ; DMET ; drug metabolism and transport ; PHH ; primary human hepatocytes ; PPARα ; peroxisome proliferator-activated receptor alpha (NR1C1) ; PXR ; pregnane X receptor (NR1I2) ; WY14 ; 643 ; [[4-chloro-6-[(2 ; 3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-acetic acid

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

6.Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules

作者：Bryan L. Copple^a ; ^{copple@msu.edu" class="auth_mail" title="E-mail the corresponding author} ; Tiangang Li^b

关键词：ABCB ; ATP-binding cassette sub-family B ; Apo ; apolipoprotein ; ASBT ; apical sodium dependent bile acid transporter ; BDL ; bile duct ligation ; BSEP ; bile salt export pump ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; C/EBP ; CCAAT-enhancer-binding protein ; CES- 1 ; carboxyl esterase-1 ; CFTR ; cystic fibrosis transmembrane conductance regulator ; CGRP ; calcitonin gene-related peptide ; CHO ; Chinese hamster ovary ; ChREBP ; carbohydrate response element binding protein ; CREB ; cAMP response element-binding

刊名：Pharmacological Research

出版年：2016

7.Indirubin, a component of Ban-Lan-Gen, activates CYP3A4 gene transcription through the human pregnane X receptor

作者：Takeshi Kumagai^a ; ^{ta-kuma@tohoku-pharm.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yusuke Aratsu^a ; ^b ; Ryosuke Sugawara^a ; Takamitsu Sasaki^a ; ^c ; Shinichi Miyairi^d ; Kiyoshi Nagata^a

关键词：AhR activator ; Indirubin ; CYP3A4 induction ; PXR ; Herb&ndash ; drug interactions

刊名：Drug Metabolism and Pharmacokinetics

出版年：2016

8.Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR)

作者：Keiyu Oshida^a ; ¹ ; Naresh Vasani^a ; Russell S. Thomas^b ; ² ; Dawn Applegate^c ; Frank J. Gonzalez^d ; Lauren M. Aleksunes^e ; Curtis D. Klaassen^f ; J. Christopher Corton^a ; ^{corton.chris@epa.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：Aryl hydrocarbon receptor ; Peroxisome proliferator-activated receptor ; Transcript profiling ; Liver cancer ; Constitutive activated receptor ; Keap1 ; Nrf2 ; Pregnane X receptor

刊名：Toxicology

出版年：2015

9.Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450

作者：Martina &Scaron ; těpá ; nková ; ^a ; Kristý ; na Krasulová ; ^b ; ^c ; Aneta Dořičá ; ková ; ^a ; Ondřej Kurka^d ; Pavel Anzenbacher^b ; ^c ; Zdeněk Dvořá ; k^a ; ^{moulin@email.cz" class="auth_mail" title="E-mail the corresponding author}

关键词：AhR ; Aryl Hydrocarbon Receptor ; CCBs ; calcium channel blockers ; CYP ; cytochrome P450 ; DEX ; dexamethasone ; DMSO ; dimethysulfoxide ; GR ; Glucocorticoid Receptor ; HLMs ; human liver microsomes ; PXR ; pregnane X receptor ; RIF ; rifampicin ; TCDD ; 237 ; 8 tetrachlorodibenzo-p-dioxin

刊名：Toxicology Letters

出版年：2016

10.A SUMO-acetyl switch in PXR biology

作者：Wenqi Cui^a ; Mengxi Sun^b ; Shupei Zhang^d ; Xunan Shen^a ; Nadezhda Galeva^c ; Todd D. Williams^c ; Jeff L. Staudinger^a ; ^{stauding@ku.edu" class="auth_mail" title="E-mail the corresponding author} ;

关键词：PXR ; pregnane X receptor ; TSA ; trichostatin A ; HDAC3 ; histone de-acetylase 3 ; SMRT ; silencing mediator of retinoic acid and thyroid hormone receptor ; PTM ; post-translational modification ; LC&ndash ; MS/MS ; liquid chromatography&ndash ; tandem mass spectrometry ; PIAS1 ; protein inhibitor of activated STAT-1 ; SUMO ; small ubiquitin-related modifier ; Rif ; rifampicin ; PCN ; pregnenolone 16α-carbonitrile ; RFP ; red fluorescent protein ; GFP ; green fluorescent protein

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

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