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在“Elsevier电子期刊”中，命中：42条，耗时：0.1379345 秒

在所有数据库中总计命中：67条

1.Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans

作者：Lei Li¹ ; ² ; ^&dagger ; ; Giulia M. Pilo³ ; ^&dagger ; ; Xiaolei Li² ; ⁴ ; ^&dagger ; ; Antonio Cigliano⁵ ; Gavinella Latte³ ; Li Che² ; Christy Joseph⁵ ; Marta Mela³ ; Chunmei Wang² ; Lijie Jiang² ; Silvia Ribback⁵ ; Maria M. Simile³ ; Rosa M. Pascale³ ; Frank Dombrowski⁵ ; Matthias Evert⁵ ; Clay F. Semenkovich⁶ ; Xin Chen² ; Diego F. Calvisi³ ; ^{calvisid@uniss.it" class="auth_mail" title="E-mail the corresponding author}

关键词：ACAC ; acetyl-CoA carboxylase ; ACLY ; adenosine triphosphate citrate lyase ; AKT ; v-akt murine thymoma viral oncogene homolog ; ELOVL5 ; elongation of very long chain fatty acids protein 5 ; FASN ; fatty acid synthase ; HCC ; hepatocellular carcinoma ; LDH ; lactate dehydrogenase ; mTOR ; mammalian target of rapamycin ; mTORC ; mTOR complex ; N-Ras ; neuroblastoma Ras viral oncogene homolog ; PKM2 ; pyruvate kinase M2 isoform ; Raptor ; regulatory-associated protein of mTOR ; Rictor ; rapamycin-insensitive companion o

刊名：Journal of Hepatology

出版年：2016

2.Role of mTOR in glioblastoma

作者：Zekeriya Duzgun ; Zuhal Eroglu ; Cigir Biray Avci

关键词：mTOR ; mammalian target of rapamycin ; mTOR ; mammalian target of rapamycin ; PI3K ; phosphoinositide 3-kinase ; RICTOR ; rapamycin-insensitive companion of mTOR ; RAPTOR ; regulatory-associated protein of mTOR ; mTORC1 ; mammalian target of rapamycin complex 1 ; DEPTOR ; DEP domain-containing mTOR-interacting protein ; FKBP12 ; FK506-binding intracellular protein ; TSC1 ; Tuberous sclerosis complex 1 ; TSC2 ; tuberous sclerosis complex 2 ; Akt ; Protein kinase B ; PDK1 ; Pyruvate dehydrogenase lipoamide kinase isozym

刊名：Gene

出版年：2016

3.Metformin attenuates graft-versus-host disease via restricting mammalian target of rapamycin/signal transducer and activator of transcription 3 and promoting adenosine monophosphate-activated protein kinase-autophagy for the balance between T helper 17 and Tregs

作者：Min-Jung Park^a ; ¹ ; Seon-Yeong Lee^a ; ¹ ; Su-Jin Moon^b ; ¹ ; Hye-Jin Son^a ; Sung-Hee Lee^a ; Eun-Kyung Kim^a ; Jae-Kyeong Byun^a ; Dong Yun Shin^c ; Sung-Hwan Park^a ; Chul-Woo Yang^d ; ² ; ^{yangch@catholic.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Mi-La Cho^a ; ² ; ^{iammila@catholic.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：aGVHD ; acute graft-versus-host disease ; BMT ; bone marrow transplantation ; AMPK ; Adenosine monophosphate&ndash ; activated protein kinase ; Treg ; regulatory T ; Th ; T helper cell ; STAT3 ; signal transducer and activator of transcription ; mTOR ; mammalian target of rapamycin

刊名：Translational Research

出版年：2016

4.Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease

作者：Chunyang Du^a ; ^b ; ¹ ; ^{duchunyang55@163.com" class="auth_mail" title="E-mail the corresponding author} ; Ming Wu^a ; ^b ; ¹ ; Huan Liu^c ; ¹ ; Yunzhuo Ren^a ; ^b ; ^{renyunzhuo1978@163.com" class="auth_mail" title="E-mail the corresponding author} ; Yunxia Du^a ; ^b ; Haijiang Wu^a ; ^b ; Jinying Wei^a ; ^b ; Chuxin Liu^c ; Fang Yao^a ; ^b ; Hui Wang^a ; ^b ; Yan Zhu^d ; Huijun Duan^a ; ^b ; ^{duanhj999@163.com" class="auth_mail" title="E-mail the corresponding author} ; Yonghong Shi^a ; ^b ; ^{yonghongshi@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Diabetic nephropathy ; TXNIP ; Lipid accumulation ; Akt/mTOR ; SREBP-1 ; PPARα

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

5.Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice

关键词：AIF ; apoptosis-inducing factor ; CEL ; carboxyethyl-lysine ; CML ; carboxymethyl-lysine ; DBI ; Double Bond Index ; FRL ; % free radical leak ; GSA ; glutamic semialdehyde ; MDAL ; malondialdehyde-lysine ; mitROSp ; mitochondrial ROS production ; mtDNA ; mitochondrial DNA ; mTOR ; mammalian target of rapamycin ; 8-oxodG ; 8-oxo-7 ; 8-dihydro-2&prime ; deoxyguanosine ; PI ; Peroxidizability Index ; RAPTOR ; regulatory-associated protein of m-TOR ; ROS ; reactive oxygen species ; RCR ; respiratory control ratio ; 2-SC ; succinyl-c

刊名：Experimental Gerontology

出版年：2016

6.mTORC1 Is a Major Regulatory Node in the FGF21 Signaling Network in Adipocytes

作者：Annabel Y. Minard¹ ; ² ; Shi-Xiong Tan³ ; ⁷ ; Pengyi Yang² ; ⁴ ; Daniel J. Fazakerley² ; Westa Domanova² ; Benjamin L. Parker² ; Sean J. Humphrey² ; Raja Jothi⁵ ; Jacqueline Stö ; ckli² ; David E. James² ; ⁶ ; ⁸ ; ^{david.james@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：FGF21 ; mTORC1 ; mTOR ; UCP1 ; phosphoproteomics ; phosphoproteome ; adipocyte ; signaling ; insulin resistance ; obesity

刊名：Cell Reports

出版年：2016

7.Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes

作者：Shruti Chowdhari ; Neeru Saini ; ^{nsaini@igib.in" class="auth_mail" title="E-mail the corresponding author}

关键词：PUVA ; 8-methoxypsoralen plus UVA ; RIG-1 ; retinoic acid induced gene 1 ; MDA5 ; melanoma differentiation associated gene 5 ; MAVS ; mitochondrial antiviral signaling protein ; TBK ; TANK-binding kinase 1 ; IKKε ; inhibitor of kappaB kinase epsilon ; IRF3 ; interferon regulatory factor 3 ; AKT ; v-akt murine thymoma viral oncogene homolog 1 ; mTOR ; mechanistic target of rapamycin ; FAS ; fas cell surface death receptor ; UBE2N ; ubiquitin conjugating enzyme E2N ; 3'UTR ; 3&prime ; untranslated region ; MDM2 ; murine do

刊名：Cellular Signalling

出版年：2016

8.MicroRNA-451 regulates AMPK/mTORC1 signaling and fascin1 expression in HT-29 colorectal cancer

作者：Min-Bin Chen ; Mu-Xin Wei ; Jun-Yi Han ; Xiao-Yang Wu ; Chen Li ; Jian Wang ; Wei Shen ; Pei-Hua Lu

关键词：AMPK ; AMP-activated protein kinase ; ACC ; Acetyl-CoA Carboxylase ; AICAR ; 5-aminoimidazole-4-carboxamide-1-尾-d-ribofuranoside ; CAB39 ; calcium-binding protein 39 ; FSCN1 ; fascin1 ; mammalian target of rapamycin (mTOR) ; mTORC1 ; mTOR complex 1 ; Raptor ; regulatory associated protein of mTOR ; RNAi ; RNA interference ; S6K1 ; ribosomal p70 S6 kinase ; TSC2 ; Tuberous sclerosis protein 2 and untranslated regions (UTRs)

刊名：Cellular Signalling

出版年：January, 2014

9.RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

作者：Bradley S. Gordon ; Abid A. Kazi ; Catherine S. Coleman ; Michael D. Dennis ; Vincent Chau ; Leonard S. Jefferson ; Scot R. Kimball

关键词：4E-BP1 ; eukaryotic initiation factor 4E binding protein 1 ; caRags ; constitutively active Rags B and C ; caRheb ; constitutively active Rheb ; caRhoA ; constitutively active RhoA ; mTOR ; mechanistic target of rapamycin ; mTORC ; mechanistic target of rapamycin complex ; p70S6K1 ; 70 ; kDa ribosomal protein S6 kinase 1 ; PRAS40 ; proline-rich Akt/PKB substrate 40 ; kDa ; RAPTOR ; regulatory-associated protein of mTOR ; complex 1 ; RICTOR ; RAPTOR-independent companion of mTOR ; Sin1 ; stress-activated map kin

刊名：Cellular Signalling

出版年：March, 2014

10.A role for Raptor phosphorylation in the mechanical activation of mTOR signaling

作者：John W. Frey ; Brittany L. Jacobs ; Craig A. Goodman ; Troy A. Hornberger

关键词：EC ; eccentric contraction ; G尾L ; G-protein 尾-subunit-like protein ; GFP ; green fluorescent protein ; JNK ; c-jun n-terminal kinase ; MAPK ; mitogen-activated protein kinase ; mLST8 ; lethal with sec13 protein 8 ; mTOR ; mammalian [or mechanistic] target of rapamycin ; mTORC1 ; mTOR complex 1 ; mTORC2 ; mTOR complex 2 ; p38 ; p38 mitogen-activated protein kinase ; p70S6k ; ribosomal S6 kinase 1 ; PI3K ; phosphotidylinositol-3-kinase ; PRAS40 ; proline-rich Akt substrate of 40 ; kDa ; Raptor ; regulatory associated

刊名：Cellular Signalling

出版年：February, 2014

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