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1.Effect of cholecystectomy on bile acids as well as relevant enzymes and transporters in mice: Implication for pharmacokinetic changes of rifampicin

作者：Fan Zhang^a ; ^b ; Hongyan Qin^b ; Yanshu Zhao^a ; ^b ; Yuhui Wei^b ; Lili Xi^b ; Zhi Rao^b ; Jianping Zhang^b ; Yanrong Ma^b ; Yingting Duan^a ; ^b ; Xinan Wu^b ; ^{xinanwu6511@126.com}

关键词：Asbt ; apical sodium-dependent bile acids transporter ; BAs ; bile acids ; Bsep ; bile salt export pump ; β-MCA ; β-muricholic acid ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; Cyp3a11 ; cytochrome P450 3a11 (human CYP3A4) ; Cyp7a1 ; cholesterol 7α-hydroxylase cytochrome P450 7a1 ; DCA ; deoxycholic acid ; Fxr ; farnesoid X receptor ; G- ; glycine conjugated bile acid ; HDCA ; hyodesoxycholic acid ; LCA ; lithocholic acid ; Mrp2 ; multidrug resistance-associated protein 2 ; NDCA ; demethylation deoxycholic acid ; NRs

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Fibroblasts and macrophages: Key players in the head and neck cancer microenvironment

作者：Kusumawadee Utispan ; Sittichai Koontongkaew ; ^{koontongkaew@gmail.com}

关键词：(TGF-β) ; transforming growth factor-beta ; (VEGF) ; vascular endothelial growth factor ; (TNF-α) ; tumor necrosis factor-alpha ; (HGF) ; hepatocyte growth factor ; (IL-1α) ; interleukin-1alpha ; (IL1-β) ; interleukin-1beta ; (IL-6) ; interleukin-6 ; (IL-33) ; interleukin-33 ; (SDF-1/CXCL12) ; stromal cell-derived factor-1 ; (MMPs) ; matrix metalloproteinases

刊名：Journal of Oral Biosciences

出版年：2017

3.Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress

作者：Bing-Hang Li^a ; ¹ ; Fang-Ping He^b ; ¹ ; Xin Yang^c ; Yuan-Wen Chen^a ; ^{drchenyuanwen@163.com} ; Jian-Gao Fan^a ; ^{fattyliver2004@126.com}

关键词：CCL5 ; chemokine (C-C motif) ligand 5 ; RANTES ; regulated upon activation normal T-cell expressed and secreted ; CCR5 ; C-C chemokine receptor type 5 ; NAFLD ; nonalcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; HFD ; high-fat-diet ; α-SMA ; alpha smooth muscle actin ; TGF-β ; transforming growth factor-β ; FFA ; free fatty acid ; MMP-2 ; matrix metalloproteinase-2 ; C/EBP-β ; CCAAT/enhancer-binding protein-β ; NF-κB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; XBP-1 ; X box

刊名：Translational Research

出版年：2017

4.Regulation, Signaling, and Physiological Functions of G-Proteins

作者：Viktoriya Syrovatkina ; Kamela O. Alegre ; Raja Dey ; Xin-Yun Huang ; ^{xyhuang@med.cornell.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCR ; G-protein-coupled receptor ; G-protein ; guanine-nucleotide-binding regulatory proteins ; β2-AR ; β2-adrenergic receptor ; GPR ; G-protein regulator ; GBA ; Gα-binding and activating ; RGS ; regulators of G-protein signaling ; RTK ; receptor tyrosine kinase ; GEF ; guanine nucleotide exchange factor ; GAP ; GTPase-activating protein ; TM ; transmembrane ; β1-AR ; β1-adrenergic receptor ; GIV ; Gα-interacting-vesicle-associated protein ; IP3 ; inositol trisphosphate ; DAG ; diacylglycerol ; PDGF ; platelet-derived gro

刊名：Journal of Molecular Biology

出版年：2016

5.The impact of RGS and other G-protein regulatory proteins on Gα_i-mediated signaling in immunity

作者：John H. Kehrl ; ^{jkehrl@niaid.nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：G-protein ; RGS proteins ; Chemokine receptors ; Sphingosine 1-phosphate ; Cell trafficking

刊名：Biochemical Pharmacology

出版年：2016

6.Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators

作者：Kimberly O. Cameron^a ; ^{kimberly.o.cameron@pfizer.com" class="auth_mail" title="E-mail the corresponding author} ; Ravi G. Kurumbail^b

关键词：ACC ; acetyl-CoA carboxylase ; ADaM ; allosteric drug and metabolite ; AID ; auto-inhibitory domain ; α-RIM ; α-regulatory interacting motif ; AMPK ; adenosine monophosphate-activated protein kinase ; ASMS ; affinity selection mass spectrometry ; CamKKβ ; Ca2+/calmodulin-dependent protein kinase kinase-beta ; CBM ; carbohydrate binding module ; CBS ; cystathionine-β-synthase ; DNL ; de novo lipogenesis ; GLUT4 ; glucose transporter type 4 ; HDAC ; histone deacetylase ; HMG-CoA reductase ; 3-hydroxy-3-methyl-glutaryl-coe

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway

作者：Ting Bai^a ; ^b ; ¹ ; Yong Yang^a ; ¹ ; You-Li Yao^a ; Peng Sun^c ; Li-Hua Lian^a ; Yan-Ling Wu^a ; ^{ylwu@ybu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Ji-Xing Nan^a ; ^c ; ^{jxnan@ybu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：α-SMA ; α-smooth muscle actin ; AICAR ; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside ; ALD ; alcoholic liver disease ; ALT ; alanine aminotransferase ; AMPK ; adenosine monophosphate-activated protein kinase ; AST ; aspartate aminotransferase ; FAS ; fatty acid synthase ; HSCs ; hepatic stellate cells ; LKB-1 ; liver kinase B-1 ; NF-κB ; nuclear factor-kappa B ; PDTC ; pyrrolidinedithiocarbamic acid ; SIRT1 ; sirtuin 1 ; SREBP-1 ; sterol regulatory element-binding protein-1 ; STAT3 ; signal transducer and activator

刊名：Pharmacological Research

出版年：2016

8.Acute hyperthermic responses of heat shock protein and estrogen receptor mRNAs in rainbow trout hepatocytes

作者：Yudong Jia^a ; ^b ; Timothy D. Cavileer^a ; James J. Nagler^a ; ^{jamesn@uidaho.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Heat shock protein ; Estrogen receptor ; Vitellogenin ; Hepatocyte ; Fish

刊名：Comparative Biochemistry and Physiology - Part A: Molecular & Integrative Physiology

出版年：2016

9.Overexpression of miR-29b reduces collagen biosynthesis by inhibiting heat shock protein 47 during skin wound healing

作者：Yumin Zhu^a ; Zhongwu Li^b ; Yanling Wang^a ; Lin Li^c ; Dongmiao Wang^b ; Wei Zhang^d ; Laikui Liu^a ; ^d ; Hongbing Jiang^a ; ^b ; Jianrong Yang^b ; ^{jianrong_yangnj@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jie Cheng^a ; ^b ; ^{leonardo_cheng@163.com" class="auth_mail" title="E-mail the corresponding author} ; ^{jianrong_yangnj@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ECM ; extracellular matrix ; HSP47 ; heat shock protein 47 ; miR-29 ; microRNA-29 ; 3&prime ; -UTR ; 3&prime ; untranslated region ; IL-1β ; interleukin-1 beta ; TNF-α ; tumor necrosis factor-alpha ; TGF-β ; transforming growth factor-beta ; PDGF ; platelet-derived growth factor ; immunohistochemical staining ; IHC ; immunofluorescence ; IF ; VEGF ; vascular endothelial growth factor

刊名：Translational Research

出版年：2016

10.Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease

作者：Chunyang Du^a ; ^b ; ¹ ; ^{duchunyang55@163.com" class="auth_mail" title="E-mail the corresponding author} ; Ming Wu^a ; ^b ; ¹ ; Huan Liu^c ; ¹ ; Yunzhuo Ren^a ; ^b ; ^{renyunzhuo1978@163.com" class="auth_mail" title="E-mail the corresponding author} ; Yunxia Du^a ; ^b ; Haijiang Wu^a ; ^b ; Jinying Wei^a ; ^b ; Chuxin Liu^c ; Fang Yao^a ; ^b ; Hui Wang^a ; ^b ; Yan Zhu^d ; Huijun Duan^a ; ^b ; ^{duanhj999@163.com" class="auth_mail" title="E-mail the corresponding author} ; Yonghong Shi^a ; ^b ; ^{yonghongshi@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Diabetic nephropathy ; TXNIP ; Lipid accumulation ; Akt/mTOR ; SREBP-1 ; PPARα

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

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