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Elsevier电子期刊(38)

在“Elsevier电子期刊”中，命中：38条，耗时：0.0799314 秒

在所有数据库中总计命中：76条

1.Pharmacokinetics and tissue distribution of 5,7-dimethoxyflavone in mice following single dose oral administration

作者：Di Bei^a ; Guohua An^b ; ^{guohua-an@uiowa.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：5 ; 7-DMF ; 5 ; 7-Dimethoxyflavone ; PK ; pharmacokinetic ; LC&ndash ; MS/MS ; Liquid chromatography&ndash ; tandem mass spectrometry ; CYP ; Cytochrome P450 ; P-gp ; P-glycoprotein ; MRP ; multidrug resistance associated-proteins ; BCRP ; Breast Cancer Resistance Protein ; MDR ; multidrug resistance ; LLOQ ; lower limit of quantification ; PBS ; phosphate-buffered saline ; I.S ; internal standard ; QC ; quality control ; HPL ; Chigh performance liquid chromatogram ; NCA ; non-compartmental analysis ; XIC ; extracted ion chromatogr

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2016

2.Simultaneous quantification of tenofovir, emtricitabine, rilpivirine, elvitegravir and dolutegravir in mouse biological matrices by LC-MS/MS and its application to a pharmacokinetic study

作者：Pavan Kumar Prathipati ; ^{Pavankumarprathipati@creighton.edu" class="auth_mail" title="E-mail the corresponding author} ; Subhra Mandal ; Christopher J. Destache

关键词：Antiretroviral ; LC&ndash ; MS/MS ; Pharmacokinetic ; Tissue distribution ; Plasma

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2016

3.Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions

关键词：AUC ; area under the plasma concentration-time curve ; B/P ; blood-to-plasma ratio ; CYP ; cytochrome P450 ; CLint ; intrinsic clearance ; Cmax ; maximum plasma concentration ; CLPD ; passive permeability-surface area product ; DDI ; drug&ndash ; drug interaction ; fa ; fraction absorbed ; Jmax ; maximum rate of active transport ; JOCT1 ; rate of OCT1 transport ; JOCT2 ; rate of OCT2 transport ; ka ; absorption rate constant ; Ki ; inhibition constant ; Km ; Michaelis constant ; Kp ; tissue to plasma partition coefficient ; MA

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

4.Synthesis and evaluation of an ¹⁸F-labeled pyrimidine-pyridine amine for targeting CXCR4 receptors in gliomas

作者：Dustin Wayne Demoin^a ; Masahiro Shindo^b ; Hanwen Zhang^a ; Kimberly J. Edwards^a ; Inna Serganova^b ; Naga Vara Kishore Pillarsetty^a ; ^d ; Jason S. Lewis^a ; ^c ; ^d ; Ronald G. Blasberg^a ; ^b ; ^c ; ^d ; ^{blasberg@neuro1.mskcc.org" class="auth_mail" title="E-mail the corresponding author}

关键词：18F ; Radiosynthesis ; CXCR4 ; Dipyrimidine amine ; Pyrimidine-pyridine amine

刊名：Nuclear Medicine and Biology

出版年：2016

5.Formulation and evaluation of co-prodrug of flurbiprofen and methocarbamol

作者：Neela Bhatia ; ^{neela.bhatia20@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Kiran Katkar ; Snehal Ashtekar

关键词：NSAIDs ; Flurbiprofen ; Skeletal muscle relaxant ; Methocarbamol ; Ester prodrug ; RP-HPLC ; Ulcerogenicity

刊名：Asian Journal of Pharmaceutical Sciences

出版年：2016

6.A hybrid approach to advancing quantitative prediction of tissue distribution of basic drugs in human

作者：Patrick Poulin^a ; ^{patrick-poulin@videotron.ca} ; Sean Ekins^b ; ^c ; ^d ; Frank-Peter Theil^e

关键词：Animal alternatives ; Disposition ; Pharmacokinetics ; Physiological modeling ; PBPK modeling ; Distribution ; Tissue ; plasma partition coefficients ; Volume of distribution

刊名：Toxicology and Applied Pharmacology

出版年：2011

7.General approach for the calculation of tissue to plasma partition coefficients

作者：Walter Schmitt

关键词：Tissue ; plasma partition coefficients ; Tissue distribution ; Tissue exposure ; PBPK modeling

刊名：Toxicology in Vitro

出版年：2008

8.A unified algorithm for predicting partition coefficients for PBPK modeling of drugs and environmental chemicals

作者：Thomas Peyret ; Patrick Poulin ; Kannan Krishnan

关键词：Partition coefficients ; PBPK modeling ; Tissue distribution ; Tissue ; blood ; Tissue ; plasma

刊名：Toxicology and Applied Pharmacology

出版年：2010

9.A rapid LC-MS/MS method for the quantitation of a series of benzonaphthyridine derivatives: Application to in vivo pharmacokinetic and lipophilicity studies in drug development

作者：Pradeep B. Lukka^a ; ^b ; James W. Paxton^b ; Graham J. Atwell^a ; Philip Kestell^a ; Bruce C. Baguley^a ; ^{b.baguley@auckland.ac.nz}

关键词：Lipophilicity ; Antitumour ; Benzonaphthyridine ; LC&ndash ; MS/MS ; Topoisomerase poison ; SN 28049

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2012

10.Specific pathways for the incorporation of dissolved barium and molybdenum into the bivalve shell: An isotopic tracer approach in the juvenile Great Scallop (Pecten maximus)

作者：Hé ; lè ; ne Tabouret^a ; ^{tabouret@mnhn.fr} ; Sé ; bastien Pomerleau^a ; ^c ; Auré ; lie Jolivet^b ; Christophe Pé ; cheyran^a ; Ricardo Riso^b ; Julien Thé ; bault^b ; Laurent Chauvaud^b ; David Amouroux^a

关键词：Isotopes ; Femtosecond laser ablation ; Scallop shell ; Barium ; Molybdenum ; Pecten maximus ; Tracers ; Biogeochemical cycle

刊名：Marine Environmental Research

出版年：2012

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