搜索页_ triple transgenic Alzheimer s disease

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Elsevier电子期刊(37)

在“Elsevier电子期刊”中，命中：37条，耗时：0.068967 秒

在所有数据库中总计命中：47条

1.12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice

作者：Antonio Di Meco^a ; Jian-Guo Li^a ; Benjamin E. Blass^b ; Magid Abou-Gharbia^b ; Elisabetta Lauretti^a ; Domenico Praticò ; ^a ; ^{praticod@temple.edu}

关键词：Alzheimer&rsquo ; s disease ; Amyloid beta ; Animal model ; Autophagy ; Tau protein ; 12/15-Lipoxygenase

刊名：Biological Psychiatry

出版年：2017

2.Hippocampal neurogenesis in the APP/PS1/nestin-GFP triple transgenic mouse model of Alzheimer’s disease

作者：Q. Zeng^a ; M. Zheng^b ; T. Zhang^a ; G. He^a ; ^c ; ^{guiqionghe@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：2xTgAD ; APP/PS1 double transgenic mice ; 3xTgAD ; APP/PS1/nestin-GFP triple transgenic mice ; Aβ ; amyloid-β ; AD ; Alzheimer&rsquo ; s disease ; ANOVA ; analysis of variance ; APP ; amyloid precursor protein ; BrdU ; 5-bromo-2-deoxyuridine ; DCX ; doublecortin ; DG ; dentate gyrus ; LVs ; lateral ventricles ; NPCs ; neural progenitors ; NSCs ; neural stem cells ; PBS ; phosphate-buffered saline ; PS1 ; presenilin-1 ; SEM ; standard error of the mean ; SGZ ; subgranular zone ; SVZ ; subventricular zone ; WT ; wild-type littermates

刊名：Neuroscience

出版年：2016

3.Astrocytes in physiological aging and Alzheimer’s disease

作者：J.J. Rodrí ; guez-Arellano^a ; ^b ; ^{j.rodriguez-arellano@ikerbasque.org" class="auth_mail" title="E-mail the corresponding author} ; V. Parpura^c ; ^d ; R. Zorec^e ; ^f ; A. Verkhratsky^a ; ^b ; ^e ; ^f ; ^g ; ^{Alexej.Verkhratsky@manchester.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：3xTg-AD ; triple transgenic mice model of Alzheimer&rsquo ; s disease ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; ATP ; adenosine triphosphate ; CA1 ; Cornu Ammonis 1 ; CNS ; Central nervous system ; DG ; dentate gyrus ; GABA ; γ-aminobutyric acid ; GFAP ; glial fibrillary acidic protein ; GS ; glutamine synthetase ; iNOS ; inducible nitric oxide synthetase ; InsP3 ; inositol 14 ; 5-trisphosphate ; mGluR5 ; metabotropic glutamate receptor 5 ; NFAT ; nuclear factor of activated T-cells ; PS1 ; presenili

刊名：Neuroscience

出版年：2016

4.Activity of muscarinic, galanin and cannabinoid receptors in the prodromal and advanced stages in the triple transgenic mice model of Alzheimer’s disease

作者：Ivá ; n Manuel^a ; Laura Lombardero^a ; Frank M. LaFerla^c ; Lydia Gimé ; nez-Llort^b ; Rafael Rodrí ; guez-Puertas^a ; ^{rafael.rodriguez@ehu.es" class="auth_mail" title="E-mail the corresponding author}

关键词：βA ; β-amyloid ; AD ; Alzheimer&rsquo ; s disease ; EGTA ; ethylene glycol tetraacetic acid ; NTg ; non-transgenic

刊名：Neuroscience

出版年：2016

5.LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer’s disease

作者：Adriá ; n G. Sandoval-Herná ; ndez^a ; ¹ ; Alejandro Restrepo^a ; ¹ ; Gloria P. Cardona-Gó ; mez^b ; Gonzalo Arboleda^a ; ^{gharboledab@unal.edu.co" class="auth_mail" title="E-mail the corresponding author} ; ^{garboled@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AD ; Alzheimer&rsquo ; s disease ; BBB ; blood brain barrier ; Aβ ; Amyloid beta ; LRP1 ; low-density lipoprotein related protein 1 ; LXR ; liver X receptor ; GFAP ; glial fibrillary acidic protein ; Iba1 ; ionized calcium-binding adapter molecule 1

刊名：Neuroscience Letters

出版年：2016

6.Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer’s disease

作者：Hajime Shishido^a ; Yasushi Kishimoto^b ; ^{kishimot@kph.bunri-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Nobuyuki Kawai^c ; ^{nobu@kagawa-reha.net" class="auth_mail" title="E-mail the corresponding author} ; Yasunori Toyota^a ; Masaki Ueno^d ; Takashi Kubota^b ; Yutaka Kirino^b ; Takashi Tamiya^a

关键词：Aβ ; β&minus ; amyloid ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid&minus ; β precursor protein ; MWM ; Morris water maze ; TBI ; traumatic brain injury

刊名：Neuroscience Letters

出版年：2016

7.Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer’s disease

关键词：O-GlcNAcylation ; 3xTg-AD mice ; tau protein ; hippocampus

刊名：Pharmacological Research

出版年：2016

8.Progressive age-related changes in sleep and EEG profiles in the PLB1_Triple mouse model of Alzheimer鈥檚 disease

作者：Amar Jyoti ; Andrea Plano ; Gernot Riedel ; Bettina Platt ; ^{b.platt@abdn.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：APP ; PS1 ; Tau ; Sleep ; EEG ; Alzheimer&rsquo ; s disease

刊名：Neurobiology of Aging

出版年：2015

9.CDK5 knockdown in astrocytes provide neuroprotection as a trophic source via Rac1

作者：Rafael André ; s Posada-Duque ; Valentina Palacio-Castañ ; eda ; Gloria Patricia Cardona-Gó ; mez ; ^{patricia.cardona@neurociencias.udea.edu.co" class="auth_mail" title="E-mail the corresponding author}

关键词：CDK5 ; cyclin-dependent kinase ; GLU ; glutamate ; AD ; Alzheimer's disease ; DIV ; day in vitro ; ROS ; reactive oxygen species ; BDNF ; brain-derived neurotrophic factor ; ROCK ; Rho kinase ; LDH ; lactate dehydrogenase ; G-LISA ; GTP enzyme-linked immunosorbent assay ; Raci ; Rac inhibitor ; EAAT ; excitatory amino-acid transporter ; 3 ; × ; ; Tg-AD ; triple transgenic Alzheimer mice ; AAV ; adeno-associated virus ; shRNA-miR ; short hairpin RNA in a microRNA backbone ; PAK ; p21-activated kinase ; SCR ; scramble

刊名：Molecular and Cellular Neuroscience

出版年：2015

10.Estrogen: A master regulator of bioenergetic systems in the brain and body

作者：Jamaica R. Rettberg ; Jia Yao ; Roberta Diaz Brinton

关键词：3xTgAD ; triple-transgenic mouse model of Alzheimer&rsquo ; s disease ; 伪ERKO ; ER伪 knockout ; 伪KGDH ; 伪-ketoglutarate dehydrogenase ; A尾 ; amyloid beta1&ndash ; 42 ; beta-amyloid ; AD ; Alzheimer&rsquo ; s disease ; ArKO ; aromatase knockout ; BMI ; body-mass index ; CEE ; conjugated equine estrogen ; CMRglu ; cerebral metabolic rate of glucose uptake ; COX ; complex IV ; CSF ; cerebrospinal fluid ; DPN ; diarylpropionitrile (an ER尾-selective agonist) ; E1 ; estrone ; E2 ; estradiol ; 17尾-estradiol ; E3 ; estriol ; Estrogen

刊名：Frontiers in Neuroendocrinology

出版年：January, 2014

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