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Elsevier电子期刊(60)

在“Elsevier电子期刊”中，命中：60条，耗时：0.0679664 秒

在所有数据库中总计命中：95条

1.Novel 11尾-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold

作者：Rosana Leiva^a ; Constantí ; Seira^b ; Andrew McBride^c ; Margaret Binnie^c ; F. Javier Luque^b ; Axel Bidon-Chanal^b ; Scott P. Webster^c ; Santiago Vá ; zquez^a ; ^{svazquez@ub.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Adamantane ; 11尾-HSD1 inhibitors ; Drug discovery ; Molecular modeling

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

2.Identification of novel 11尾-HSD1 inhibitors by combined ligand- and structure-based virtual screening

作者：Carlos F. Lagos^a ; Andrea Vecchiola^a ; Fidel Allende^b ; Cristobal A. Fuentes^a ; Juan E. Tichauer^a ; Carolina Valdivia^a ; Sandra Solari^b ; Carmen Campino^a ; ^e ; Alejandra Tapia-Castillo^a ; Rene Baudrand^a ; ^e ; Pia Villarroel^c ; Mariana Cifuentes^c ; Gareth I. Owen^d ; Cristian A. Carvajal^a ; ^e ; Carlos E. Fardella^a ; ^e ; ^{cfardella@med.puc.cl" class="auth_mail}

关键词：11尾-HSD1 ; 11尾-hydroxysteroid dehydrogenase type 1 ; 11尾-HSD2 ; 11尾-hydroxysteroid dehydrogenase type 2 ; E ; cortisol ; F ; cortisone ; HPLC-MS/MS ; high performance liquid chromatography coupled with tandem mass spectrometry ; NADPH ; nicotinamide adenine dinucleotide phosphate reduced form ; MS ; metabolic syndrome ; BGA ; 18beta-glycyrrhetinic acid

刊名：Molecular and Cellular Endocrinology

出版年：25 March, 2014

3.Synthesis and structure-activity relationship of 2-adamantylmethyl tetrazoles as potent and selective inhibitors of human 11尾-hydroxysteroid dehydrogenase type 1 (11尾-HSD1)

作者：Xiang-Yang Ye ; David Yoon ; Stephanie Y. Chen ; Akbar Nayeem ; Rajasree Golla ; Ramakrishna Seethala ; Mengmeng Wang ; Timothy Harper ; Bogdan G. Sleczka ; Atsu Apedo ; Yi-Xin Li ; Bin He ; Mark Kirby ; David A. Gordon ; Jeffrey A. Robl

关键词：11尾-Hydroxysteroid dehydrogenase type 1 (11尾-HSD1) ; Enzyme inhibitor ; Structure&ndash ; activity relationships (SAR)

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：15 January, 2014

4.11尾-Hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5伪-reductase yielding 11尾-hydroxy-5伪-androstanedione

作者：Am ; a C. Swart ; Lindie Schloms ; Karl-Heinz Storbeck ; Liezl M. Bloem ; Therina du Toit ; Jonathan L. Quanson ; William E. Rainey ; Pieter Swart

关键词：11KA4 ; 11-ketoandrostenedione ; 11KT ; 11-ketotestosterone ; 11OH-5伪-dione ; 11尾-hydroxy 5伪-androstanedione ; 11OH-AST ; 11尾-hydroxyandrosterone ; 11OHA4 ; 11尾-hydroxyandrostenedione ; 11OHT ; 11尾-hydroxytestosterone ; 11尾HSD ; 11尾-hydroxysteroid dehydrogenase ; 17OHPREG ; 17-hydroxypregnenolone ; 17OHPROG ; 17-hydroxyprogesterone ; 17尾HSD ; 17尾-hydroxysteroid dehydrogenase ; 3尾HSD ; 3尾-hydroxysteroid dehydrogenase ; A4 ; androstenedione ; ALDO ; aldosterone ; CORT ; corticosterone ; CYP17A1 ; P450 17-hydroxyla

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：November, 2013

5.Cholestatic pregnancy is associated with reduced placental 11尾HSD2 expression

作者：M. Martineau ; G. Papacleovoulou ; S. Abu-Hayyeh ; P.H. Dixon ; H. Ji ; R. Powrie ; L. Larson ; E.K. Chien ; C. Williamson

关键词：Placenta ; BeWo cells ; 11尾HSD2 ; Bile acid ; Cortisol ; Intrahepatic cholestasis of pregnancy

刊名：Placenta

出版年：January, 2014

6.Characterization of lipid droplets in steroidogenic MLTC-1 Leydig cells: Protein profiles and the morphological change induced by hormone stimulation

作者：Tomohiro Yamaguchi ; ^{tyamag@pharm.showa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Noriyuki Fujikawa ; Satomi Nimura ; Yutaro Tokuoka ; Sonoka Tsuda ; Toshihiro Aiuchi ; Rina Kato ; Takashi Obama ; Hiroyuki Itabe ; ^{h-itabe@pharm.showa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Lydig cells ; Lipid droplets ; Steroidogenesis ; 17beta-HSD11 ; 3beta-HSD1 ; MLTC-1

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2015

7.Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas

作者：Liezl M. Bloem ; Karl-Heinz Storbeck ; Pieter Swart ; Therina du Toit ; Lindie Schloms ; Amanda C. Swart ; ^{acswart@sun.ac.za" class="auth_mail" title="E-mail the corresponding author}

关键词：HPLC&ndash ; mass spectrometry ; UPC² ; &ndash ; MS/MS steroid analyses ; 11尾HSD ; PCOS ; LNCaP prostate cancer cell model ; H295R adrenal cell model

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2015

8.Neuroinflammation in the normal aging hippocampus

作者：R.M. Barrientos ; ^{ruth.barrientos@colorado.edu" class="auth_mail" title="E-mail the corresponding author} ; M.M. Kitt ; L.R. Watkins ; S.F. Maier

关键词：11尾-HSD1 ; 11尾-hydroxysteroid dehydrogenase type 1 ; BDNF ; brain-derived neurotrophic factor ; CCI ; controlled cortical impact ; CD11b ; complement receptor 3 ; CORT ; corticosterone ; ERK ; extracellular signal-regulated protein kinase ; GC ; glucocorticoid ; GLT1 ; glutamate transporter subtype 1 ; GR ; glucocorticoid receptor ; ICM ; intra cisterna magna ; IL-1RA ; IL-1 receptor antagonist ; IL-1尾 ; interleukin-1 beta ; IL-6 ; interleukin-6 ; JNK ; c-jun N-terminal kinase ; LPS ; lipopolysaccharide ; LTP ; long-term pote

刊名：Neuroscience

出版年：2015

9.Expression of 11尾-hydroxysteroid dehydrogenase isoforms in canine adrenal glands treated with trilostane

作者：Takahiro Teshima ; ^{teshima63@nvlu.ac.jp" class="auth_mail} ; Hirotaka Matsumoto ; Takayuki Kumagai ; Mai Kurano ; Hidekazu Koyama

关键词：3尾-hydroxysteroid dehydrogenase ; 11尾-hydroxysteroid dehydrogenase ; Adrenal gland ; Dog ; Trilostane

刊名：The Veterinary Journal

出版年：June 2014

10.A calcium-deficient diet in pregnant, nursing rats induces hypomethylation of specific cytosines in the 11尾-hydroxysteroid dehydrogenase-1 promoter in pup liver

作者：Junji Takaya ; Anna Iharada ; Hiroyuki Okihana ; Kazunari Kaneko

关键词：CpG ; cytosine-guanine ; Gapdh ; Glyceraldehyde-3-phosphate dehydrogenase gene ; Hsd11b1 ; 11尾-hydroxysteroid dehydrogenase-1 gene ; Hsd11b2 ; 11尾-hydroxysteroid dehydrogenase-2 gene ; Nr3c1 ; glucocorticoid receptor gene ; Pck1 ; phosphoenolpyruvate carboxykinase gene ; PCR ; polymerase chain reaction ; Ppara ; rat peroxisome proliferator-activated receptor 伪 gene ; 11尾-HSD1 ; 11尾-hydroxysteroid dehydrogenase-1

刊名：Nutrition Research

出版年：November, 2013

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