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Elsevier电子期刊(61)

在“Elsevier电子期刊”中，命中：61条，耗时：小于0.01 秒

在所有数据库中总计命中：102条

1.Adenosine signalling mediates the anti-inflammatory effects of the COX-2 inhibitor nimesulide

作者：Elisabetta Caiazzo^a ; Francesco Maione^a ; Silvana Morello^b ; Andrea Lapucci^c ; Sara Paccosi^c ; Bodo Steckel^d ; Antonio Lavecchia^a ; Astrid Parenti^c ; Teresa Iuvone^a ; Jü ; rgen Schrader^d ; Armando Ialenti^a ; Carla Cicala^a ; ^{cicala@unina.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Nimesulide (PubMed CID ; 4495) ; Celecoxib (PubMed CID ; 2662) ; 4-[2-[[6-amino-9-(N-ethyl-β-d-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride (CGS21680 ; PubMed CID ; 10256643) ; -(2-[7-amino-2-[2-furyl][12 ; 4]triazolo[2 ; 3-a][13 ; 5]triazin-5-yl-amino]ethyl)phenol (ZM241385 ; PubMed CID ; 176407) ; 5&prime ; -(α ; β-methylene)diphosphate (APCP ; PubMed CID ; 16219694)

刊名：Biochemical Pharmacology

出版年：2016

2.Structure activity optimization of 6H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-a]pyrazines as Jak1 kinase inhibitors

作者：Michael Friedman^a ; ^{michael.friedman@abbvie.com" class="auth_mail" title="E-mail the corresponding author} ; Kristine E. Frank^b ; Ana Aguirre^b ; Maria A. Argiriadi^a ; Heather Davis^a ; Jeremy J. Edmunds^a ; Dawn M. George^a ; Jonathan S. George^a ; Eric Goedken^a ; Bryan Fiamengo^c ; ^&dagger ; ; Deborah Hyland^a ; Bin Li^a ; Anwar Murtaza^d ; ^&dagger ; ; Michael Morytko^a ; Gagandeep Somal^a ; Kent Stewart^b ; Edit Tarcsa^a ; Stacy Van Epps^a ; Jeffrey Voss^a ; Lu Wang^a ; Kevin Woller^b ; Neil Wishart^a

关键词：Tricyclic pyrrolopyrazines ; 6H-pyrrolo[2 ; 3-e][12 ; 4]triazolo[4 ; 3-a]pyrazines ; Jak inhibitors ; Jak selectivity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

3.Exploring the 2- and 5-positions of the pyrazolo[4,3-d]pyrimidin-7-amino scaffold to target human A₁ and A_2A adenosine receptors

作者：Lucia Squarcialupi^a ; Matteo Falsini^a ; Daniela Catarzi^a ; Flavia Varano^a ; Marco Betti^a ; Katia Varani^b ; Fabrizio Vincenzi^b ; Diego Dal Ben^c ; Catia Lambertucci^c ; Rosaria Volpini^c ; Vittoria Colotta^a ; ^{vittoria.colotta@unifi.it" class="auth_mail" title="E-mail the corresponding author}

关键词：AR ; adenosine receptor ; PD ; Parkinson&rsquo ; s disease ; CCPA ; 2-chloro-N(6)-cyclopentyladenosine ; NECA ; 5&prime ; -(N-ethyl-carboxamido)adenosine ; cAMP ; cyclic adenosine monophosphate ; Cl-IB-MECA ; 2-chloro-N6-(3-iodobenzyl)5&prime ; -(N-methylcarbamoyl)adenosine ; DPCPX ; 8-cyclopentyl-1 ; 3-dipropyl-xanthine ; ZM241385 ; 4-(2-[7-amino-2-(2-furyl)[12 ; 4]-triazolo[2 ; 3-a][13 ; 5]triazin-5-ylamino]ethyl)phenol ; I-AB-MECA ; N6-(4-amino-3-iodobenzyl)-5&prime ; -(N-methylcarbamoyl)adenosine ; EL2 ; second extracellula

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Design, synthesis, assessment, and molecular docking of novel pyrrolopyrimidine (7-deazapurine) derivatives as non-nucleoside hepatitis C virus NS5B polymerase inhibitors

作者：Mosaad S. Mohamed^a ; Amira I. Sayed^a ; Mohammed A. Khedr^b ; Sameh H. Soror^c ; ^d ; ^{sameh_soror@pharm.helwan.edu.eg" class="auth_mail" title="E-mail the corresponding author}

关键词：Antiviral drugs ; HCV ; Molecular modeling ; NS5B polymerase ; Pyrrolopyrimidine

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

5.Synthesis and biological evaluation of novel 2-amino-3-aroyl-4-neopentyl-5-substituted thiophene derivatives as allosteric enhancers of the A₁ adenosine receptor

作者：Romeo Romagnoli ; Pier Giovanni Baraldi ; Maria Dora Carrion ; Olga Cruz-Lopez ; Carlota Lopez Cara ; Giulia Saponaro ; Delia Preti ; Mojgan Aghazadeh Tabrizi ; Stefania Baraldi ; Allan R. Moorman ; Fabrizio Vincenzi ; Pier Andrea Borea ; Katia Varani

关键词：GPCRs ; G protein-coupled receptors ; [3H]DPCPX ; [3H]1 ; 3-dipropyl-8-cyclopentyl-xanthine ; [3H]MRE-3008F20 ; [3H]5-N-(4-methoxyphenylcarbamoyl)amino-8-propyl-2-(2-furyl)pyrazolo[4 ; 3-e]-12 ; 4-triazolo[1 ; 5-c]pyrimidine ; [3H]CCPA ; [3H]2-chloro-N6-cyclopentyladenosine ; [3H]ZM 241385 ; [3H](4-(2-[7-amino-2-(2-furil)[1 ; 2.4]triazolo[2 ; 3-a][13 ; 5]triazin-5-ylamino]ethyl)phenol) ; CCPA ; 2-chloro-N6-cyclopentyladenosine ; CHO ; chinese hamster ovary ; cAMP ; cyclic adenosine monophosphate ; AE(s) ; allosteric enhance

刊名：Bioorganic and Medicinal Chemistry

出版年：1 January, 2014

6.Potential role of A_2A adenosine receptor in traumatic optic neuropathy

作者：Saif Ahmad ; Nadeem Fatteh ; Nehal M. El-Sherbiny ; Mohammad Naime ; Ahmed S. Ibrahim ; Ahmed M. El-Sherbini ; Sally A. El-Shafey ; Sohail Khan ; Sadan ; Fulzele ; Joyce Gonzales ; Gregory I. Liou

关键词：TON ; traumatic optic neuropathy ; TNF-伪 ; tumor necrosis factor-伪 ; ELISA ; Enzyme-linked immunosorbent assay ; ROS ; reactive oxygen species ; MAP kinase ; Mitogen-activated protein kinase ; ERK ; extracellular signal-regulated kinase ; AR ; adenosine receptor ; CGS21680 ; 2-p-[2-Carboxyethyl]phenethylamino-5&prime ; -N-ethylcarboxamidoadenosine ; LPS ; lipopolysaccharides ; NECA ; 5&prime ; -N-Ethylcarboxamidoadenosine ; ZM241385 ; 4-(2-[7-Amino-2-(2-furyl)[12 ; 4]triazolo[2 ; 3-a][13 ; 5]triazin-5-ylamino]ethyl)phenol

刊名：Journal of Neuroimmunology

出版年：15 November, 2013

7.Synthesis and antitumor evaluation of C3/C3 fluoroquinolone dimers (I): Tethered with a fused heterocyclic s-triazolo[2,1-b][1,3,4]thiadiazole

作者：Guo Qiang Hu ; Zhong Quan Zhang ; Song Qiang Xie ; Wen Long Huang

关键词：Fluoroquinolone ; Dimer ; Antitumor evaluation

刊名：Chinese Chemical Letters

出版年：2010

8.Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A_2A receptor

作者：Alison Ribeiro^a ; Viviane Ferraz-de-Paula^a ; Milena L. Pinheiro^a ; Luana B. Vitoretti^b ; Domenica P. Mariano-Souza^c ; Wanderley M. Quinteiro-Filho^a ; Adriana T. Akamine^a ; Viní ; cius I. Almeida^a ; Joã ; o Quevedo^d ; Felipe Dal-Pizzol^d ; Jaime E. Hallak^e ; Antô ; nio W. Zuardi^e ; José ; A. Crippa^e ; Joã ; o Palermo-Neto^a ; ^{jpalermo@usp.br}

关键词：Cannabidiol ; Acute lung injury ; Adenosine A2A receptor ; Cannabinoid ; Pro-inflammatory cytokine ; Chemokine

刊名：European Journal of Pharmacology

出版年：2012

9.New condensed pyrroles of potential biological interest: Syntheses and structure–activity relationship studies

作者：Mosaad S. Mohamed ; Rehab Kamel ; Samar S. Fatahala

关键词：Pyrrole ; Pyrrolo[2 ; 3-d]pyrimidine ; Structure– ; activity-relationship ; Anti-inflammatory activity ; Antimicrobial

刊名：European Journal of Medicinal Chemistry

出版年：2011

10.Synthesis and biological activity of new 2-amino-8-chloro-5,5-dioxo[1,2,4]triazolo[2,3-b][1,4,2]benzodithiazines

作者：Elż ; bieta Pomarnacka ; Patrick J. Bednarski ; Przemys42 ; aw Reszka ; Ewa Dziemidowicz-Borys ; Andrzej Bie44 ; czak ; W42 ; adys42 ; aw Werel ; Rafa42 ; Ha42 ; asa

关键词：Triazolo[2 ; 3-b] [14 ; 2]benzodithiazines ; Cytotoxic activity ; Antibacterial activity

刊名：European Journal of Medicinal Chemistry

出版年：2006

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