作者：Ming Chen^a ; Jianting Shi^a ; Wei Zhang^b ; Linjie Huang^a ; Xiaoling Lin^a ; Zhiqiang Lv^a ; Wei Zhang^a ; Ruiyun Liang^a ; Shanping Jiang^a ; ^{shanpingjiang@126.com}

关键词：MiR-23b ; TGF-β1/Smad3 ; Asthma ; Airway smooth muscle cells

刊名：Pulmonary Pharmacology & Therapeutics

出版年：2017

作者：Sandipan Chakraborty¹ ; ^{sandipanchakraborty.13@gmail.com} ; Soumalee Basu ; ^{soumalee@gmail.com}

关键词：AD therapeutics ; BACE1 ; Aβ aggregation ; Steady-state and time-resolved fluorescence ; Molecular modeling ; AFM

刊名：International Journal of Biological Macromolecules

出版年：2017

作者：C. Walsh ; W.H.I.M. Drinkenburg ; A. Ahnaou ; ^{aahnaou@its.jnj.com}

关键词：Aβ ; amyloid Beta ; ACh ; acetylcholine ; AChEI ; acetylcholinesterase inhibitor ; ACH ; amyloid cascade hypothesis ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; ARIA-E ; amyloid related imaging abnormalities related to edema ; CSF ; cerebrospinal fluid ; EEG ; electroencephalogram/electroencephalography ; EROS ; event-related oscillations ; ERP ; event-related potentials ; fAD ; familial Alzheimer&rsquo ; s disease ; fMRI ; functional MRI ; FTDP-17 ; frontotemporal dementia and parkinsonism linked to

刊名：Neuroscience & Biobehavioral Reviews

出版年：2017

作者：Kristopher A. Sarosiek¹ ; ² ; ¹² ; Cameron Fraser¹ ; Nathiya Muthalagu³ ; Patrick D. Bhola¹ ; ² ; Weiting Chang² ; ⁴ ; Samuel K. McBrayer¹ ; ² ; Adam Cantlon² ; ⁴ ; Sudeshna Fisch² ; ⁴ ; Gail Golomb-Mello⁵ ; Jeremy A. Ryan¹ ; ² ; Jing Deng¹ ; ² ; Brian Jian⁶ ; Chris Corbett⁷ ; Marti Goldenberg⁷ ; Joseph R. Madsen² ; ⁷ ; Ronglih Liao² ; ⁴ ; Dominic Walsh² ; ⁴ ; John Sedivy⁵ ; Daniel J. Murphy³ ; ⁸ ; Daniel Ruben Carrasco¹ ; ² ; Shenandoah Robinson² ; ⁷ ; Javid Moslehi⁹ ; ¹⁰ ; ¹¹ ; Anthony Letai¹ ; ² ; ¹³ ; ^{anthony_letai@dfci.harvard.edu}

关键词：apoptosis ; radiosensitivity ; chemosensitivity ; neurotoxicity ; cardiotoxicity ; side effects of chemotherapy ; side effects of radiation therapy ; cell death regulation ; c-Myc ; pediatric cancer

刊名：Cancer Cell

出版年：2017

作者：Maciej Banach^a ; ^b ; ^c ; ^{maciejbanach77@gmail.com} ; Manfredi Rizzo^d ; ^e ; Dragana Nikolic^d ; George Howard^f ; VirginiaJ. Howard^g ; DimitriP. Mikhailidis^h

关键词：AD ; Alzheimer's disease ; Apo ; Apolipoprotein ; BP ; Blood pressure ; CHD ; Coronary heart disease ; CI ; Confidence interval ; CoQ10 ; Coenzyme Q10 ; CV ; Cardiovascular ; CVD ; Cardiovascular disease ; EBBINGHAUS ; The Evaluating PCSK9 Binding antiBody Influence oN coGnitive HeAlth in High cardiovascUlar Risk Subjects ; FDA ; Food and Drug Administration ; FOURIER ; Further cardiovascular outcomes research with PCSK9 inhibition in subjects with elevated risk ; GAUSS ; Goal achievement after utilizing an anti-PCSK9

刊名：Pharmacology & Therapeutics

出版年：2017

作者：Keiko Rausch¹ ; ⁷ ; Brent A. Hackett¹ ; ⁷ ; Nathan L. Weinbren¹ ; Sophia M. Reeder¹ ; Yoel Sadovsky⁴ ; ⁵ ; ⁶ ; Christopher A. Hunter² ; David C. Schultz³ ; Carolyn B. Coyne⁴ ; ⁵ ; ⁶ ; Sara Cherry¹ ; ⁸ ; ^{cherrys@mail.med.upenn.edu}

关键词：antivirals ; flavivirus ; arbovirus ; therapeutics ; repurposing ; drugs ; entry

刊名：Cell Reports

出版年：2017

作者：Chatchai Muanprasat ; ^{chatchai.mua@mahidol.ac.th} ; Varanuj Chatsudthipong

关键词：ACE ; angiotensin-converting enzyme ; AChE ; acetylcholine esterase ; AD ; Alzheimer's disease ; AMPK ; AMP-activated protein kinase ; AP-1 ; activator protein 1 ; Aβ ; amyloid beta ; CaSR ; calcium-sensing receptor ; COS ; chitosan oligosaccharide ; COX-2 ; cyclooxygenase-2 ; DD ; degree of deacetylation ; DM ; diabetes mellitus ; DP ; degree of polymerization ; EGFR ; epidermal growth factor receptor ; ERK 1/2 ; extracellular signal-regulated kinase ; FITC ; fluorescein isothiocyanate ; GlcN ; d-glucosamine ; GlcNAc ; N-acety

刊名：Pharmacology & Therapeutics

出版年：2017

作者：Yong Chen¹ ; Ruping Pan² ; Alexander Pfeifer ; ^{alexander.pfeifer@uni-bonn.de}

关键词：ADAM17 ; ADAM metallopeptidase domain 17 ; ADINR ; adipogenic differentiation induced noncoding RNA ; ADNCR ; adipocyte differentiation-associated long noncoding RNA ; AMPK ; AMP-activated protein kinase ; aP2 ; fatty-acid binding protein 4 ; BAT ; brown adipose tissue ; Blnc1 ; brown fat lncRNA 1 ; BMI ; body mass index ; BMP7 ; bone morphogenetic protein 7 ; BMPR1A ; bone morphogenetic protein receptor-1α ; C/EBP ; CCAAT/enhancer-binding protein ; cGMP ; cyclic GMP ; Cidea ; cell death-inducing DNA fragmentation facto

刊名：Pharmacology & Therapeutics

出版年：2017

作者：Renu Sharma ; Dhiraj Kumar ; Niraj Kumar Jha ; Saurabh Kumar Jha ; Rashmi K Ambasta ; Pravir Kumar ; ^{pravirkumar@dce.edu} ; ^{kpravir@gmail.com}

关键词：Post-mitotic cell division ; Signaling cascade ; Neuromuscular degeneration ; Cyclins ; Therapeutics

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

作者：Randall J. Bateman^a ; ^{batemanr@wustl.edu} ; Tammie L. Benzinger^b ; Scott Berry^c ; David B. Clifford^a ; Cynthia Duggan^a ; Anne M. Fagan^a ; Kathleen Fanning^a ; Martin R. Farlow^d ; Jason Hassenstab^a ; Eric M. McDade^a ; Susan Mills^a ; Katrina Paumier^a ; Melanie Quintana^c ; Stephen P. Salloway^e ; Anna Santacruz^a ; Lon S. Schneider^f ; Guoqiao Wang^g ; Chengjie Xiong^g ; the DIAN-TU Pharma Consortium for the Dominantly Inherited Alzheimer Network

关键词：Alzheimer's disease ; Alzheimer's prevention trial ; Adaptive clinical trial ; Biomarkers ; Disease progression model ; Cognitive composite ; Dose adjustment ; DIAN-TU ; Amyloid ; Tau ; Autosomal dominant Alzheimer's disease

刊名：Alzheimer's & Dementia

出版年：2017