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中国地质文献-英文(163)	SpringerLink电子期刊(24520)	GSW全文库(1218)
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在“Elsevier电子期刊”中，命中：71,572条，耗时：0.010995 秒

在所有数据库中总计命中：114,548条

1.Polar aromatic periphery increases agonist potency of spirocyclic free fatty acid receptor (GPR40) agonists inspired by LY2881835

作者：Mikhail Krasavin^a ; ^{m.krasavin@spbu.ru} ; Alexey Lukin^b ; Daria Bagnyukova^b ; Nikolay Zhurilo^b ; Aleksei Golovanov^b ; Sergey Zozulya^c ; ^d ; Ihor Zahanich^c ; Daniel Moore^e ; Irina G. Tikhonova^e

关键词：Drug discovery ; FFA1 agonists ; Antidiabetic agents ; Spirocyclic motifs ; Hydrophobic interactions ; π&minus ; π stacking

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Dopamine agonist withdrawal syndrome: A comprehensive review

作者：Xin Xin Yu ; ^yux@ccf.org ; Hubert H Fernandez

关键词：Parkinson disease ; Dopamine agonist ; Dopamine agonist withdrawal syndrome ; Impulse control disorder

刊名：Journal of the Neurological Sciences

出版年：2017

3.Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists

关键词：GPR119 agonists ; 5-Nitropyrimidine ; endo-Azabicyclic alcohol ; Full agonists

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.Molecular dynamics simulation of the human estrogen receptor alpha: contribution to the pharmacophore of the agonists

作者：Dessislava Jereva^a ; ^{dessislava.jereva@biomed.bas.bg} ; Filip Fratev^a ; ^b ; ^{fratev@biomed.bas.bg} ; Ivanka Tsakovska^a ; ^{itsakovska@biomed.bas.bg} ; Petko Alov^a ; ^{petko.alov@biophys.bas.bg} ; Tania Pencheva^a ; ^{tania.pencheva@biomed.bas.bg} ; Ilza Pajeva^a ; ^{pajeva@biomed.bas.bg}

关键词：Human estrogen receptor alpha ; Agonist ; Pharmacophore ; Molecular dynamics simulation

刊名：Mathematics and Computers in Simulation

出版年：2017

5.Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists

作者：Sheng-Ren Chen^a ; ^c ; Yi-Yu Ke^a ; ¹ ; Teng-Kuang Yeh^a ; ¹ ; Shu-Yu Lin^a ; Li-Chin Ou^a ; Shu-Chun Chen^a ; Wan-Ting Chang^a ; Hsiao-Fu Chang^a ; Zih-Huei Wu^a ; Chih-Chien Hsieh^a ; Ping-Yee Law^b ; Horace H. Loh^b ; Chuan Shih^a ; Yiu-Kay Lai^c ; ^{yklai@life.nthu.edu.tw} ; Shiu-Hwa Yeh^a ; ^d ; ^{bau9763@bp.nhri.org.tw} ; Shau-Hua Ueng^a ; ^{shueng@nhri.org.tw}

关键词：μ-opioid receptor agonist ; κ-opioid receptor agonist ; Structure-activity relationship ; Blood-brain barrier ; Penetration ; Anti-nociceptive effects ; Tail-flick test

刊名：European Journal of Medicinal Chemistry

出版年：2017

6.Inverse agonists - What do they mean for psychiatry?

作者：David Nutt^a ; ^{d.nutt@imperial.ac.uk} ; Stephen Stahl^b ; Pierre Blier^c ; Filippo Drago^d ; Joseph Zohar^e ; Sue Wilson^a

关键词：Inverse agonist ; Antagonist ; Serotonin ; 5-HT2A

刊名：European Neuropsychopharmacology

出版年：2017

7.A benzo[b]thiophene-based selective type 4 S1P receptor agonist

作者：Wooyoung Hur^a ; ¹ ; Hugh Rosen^b ; Nathanael S. Gray^a ; ^{Nathanael_Gray@dfci.harvard.edu}

关键词：Sphingosine-1-phosphate ; S1P receptor ; S1PR4 ; S1P4 ; Selective agonist

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

8.Estimation of the receptor-state affinity constants of ligands in functional studies using wild type and constitutively active mutant receptors: Implications for estimation of agonist bias

作者：Frederick J. Ehlert^a ; ^b ; ^{fjehlert@uci.edu} ; Richard S.L. Stein^b

关键词：Receptor state affinity constants ; Constitutive activity ; Agonist bias ; System bias ; Monod-Wyman-Changeux model ; Observed affinity ; Efficacy ; Receptor activation ; Active state ; Inactive state

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2017

9.Real-world effectiveness and safety of dapagliflozin therapy added to a GLP1 receptor agonist in patients with type 2 diabetes

作者：J.J. Gorgojo-Martí ; nez ; ^{jjgorgojo@fhalcorcon.es} ; C. Serrano-Moreno ^{cserranom@fhalcorcon.es} ; A. Sanz-Velasco ^{asanzv@fhalcorcon.es} ; G. Feo-Ortega ^{gfeo@gmail.com} ; F. Almodó ; var-Ruiz ^{falmodovar@fhalcorcon.es}

关键词：GLP1 receptor agonist ; SGLT-2 inhibitor ; Type 2 diabetes

刊名：Nutrition, Metabolism and Cardiovascular Diseases

出版年：2017

10.Potential role for the VDR agonist elocalcitol in metabolic control: Evidences in human skeletal muscle cells

作者：Cristina Antinozzi^a ; Clarissa Corinaldesi^a ; ^g ; Carla Giordano^b ; Annalinda Pisano^b ; Bruna Cerbelli^b ; Silvia Migliaccio^a ; Luigi Di Luigi^a ; Katia Stefanantoni^c ; Gabriella Barbara Vannelli^d ; Salvatore Minisola^e ; Guido Valesini^c ; Valeria Riccieri^c ; Andrea Lenzi^f ; Clara Crescioli^a ; ^{clara.crescioli@uniroma4.it}

关键词：VDR agonist ; Metabolism ; Inflammatory myopathy ; Human skeletal muscle cells

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

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