搜索页_Autotaxin (ATX)

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Elsevier电子期刊(83)

在“Elsevier电子期刊”中，命中：83条，耗时：小于0.01 秒

在所有数据库中总计命中：126条

1.A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity

作者：Tian-Shu Kang^a ; ¹ ; Wanhe Wang^b ; ¹ ; Hai-Jing Zhong^a ; Jia-Xin Liang^a ; Chung-Nga Ko^b ; Jin-Jian Lu^a ; Xiu-Ping Chen^a ; Dik-Lung Ma^b ; ^{edmondma@hkbu.edu.hk} ; Chung-Hang Leung^a ; ^{duncanleung@umac.mo}

关键词：Rhodium complex ; Anticancer ; Melanoma ; Autotaxin ; Inhibitor

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

2.Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition

作者：Lauren E. Ragle^a ; Dilip J. Palanisamy^a ; Margaux J. Joe^a ; Rachel S. Stein^a ; Derek D. Norman^b ; Gabor Tigyi^b ; Daniel L. Baker^a ; Abby L. Parrill^a ;

关键词：ATX/NPP2 ; autotaxin ; DIPEA ; N ; N-diisopropylethylamine ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethylsulfoxide ; GPCR ; G-protein coupled receptor ; GRI ; Genomic Research Institute ; HBTU ; O-(benzotriazol-1-yl)-NN ; N&prime ; N&prime ; -tetramethyluronium hexafluorophosphate ; LPC ; lysophosphatidylcholine ; LPA ; lysophosphatidic acid ; LysoPLD ; lysophospholipase-D ; MOE ; Molecular Operating Environment ; NPP ; nucleotide pyrophosphatase phosphodiesterase ; pNP-TMP ; p-nitrophenyl thymidine-5&prime ; -monophosphate ; p

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

3.Discovery of potent inhibitors of the lysophospholipase autotaxin

作者：Pritom Shah^a ; ; Anne Cheasty^a ; Caroline Foxton^a ; Tony Raynham^a ; Muddasar Farooq^a ; Irene Farre Gutierrez^a ; Aurore Lejeune^a ; Michelle Pritchard^a ; Andrew Turnbull^a ; Leon Pang^a ; Paul Owen^a ; Susan Boyd^a ; Alexandra Stowell^c ; Allan Jordan^c ; Niall M. Hamilton^c ; James R. Hitchin^c ; Martin Stockley^a ; Ellen MacDonald^a ; Mar Jimenez Quesada^a ; Elisabeth Trivier^a ; Jana Skeete^a ; Huib Ovaa^b ; ^&dagger ; ; Wouter H. Moolenaar^b ; Hamish Ryder^a

关键词：Autotaxin (ATX) ; Lysophosphatidic acid (LPA) ; Lysophosphatidylcholine (LPC) ; Cancer

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

4.Enteroendocrine cells are a potential source of serum autotaxin in men

作者：Ruth Bolier^a ; Dagmar Tolenaars^a ; Andreas E. Kremer^b ; Job Saris^a ; Albert Paré ; s^d ; Joanne Verheij^c ; Piter J. Bosma^a ; Ulrich Beuers^a ; Ronald P.J. Oude Elferink^a ; ^{r.p.oude-elferink@amc.uva.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：5-HT ; serotonin ; AD ; atopic dermatitis ; ATX ; autotaxin ; ALT ; alanine transaminase ; ALP ; alkaline phosphatase ; ANOVA ; analysis of variance ; AST ; aspartate transaminase ; AUC ; area under the curve ; CA ; cholic acid ; BAT ; brown adipose tissue ; BDL ; bile duct ligation ; CCK ; cholecystokinin ; cDNA ; complementary deoxyribonucleic acid ; CgA ; chromogranin A ; DCLK1 ; double cortin-like kinase 1 ; EEC ; enteroendocrine cell ; ELISA ; enzyme-linked immunosorbent assay ; ENPP2 ; ectonucleotide pyrophosphatase/phospho

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2016

5.Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin

作者：Jens Hausmann ; ^{jens.hausmann@mpi-muenster.mpg.de" class="auth_mail" title="E-mail the corresponding author} ; Willem-Jan Keune ; Agnes L. Hipgrave Ederveen¹ ; Leonie van Zeijl² ; Robbie P. Joosten ; Anastassis Perrakis ; ^{a.perrakis@nki.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：Autotaxin ; Phosphodiesterase ; Alkaline phosphatase ; X-ray crystallography ; Catalytic mechanism

刊名：Journal of Structural Biology

出版年：2016

6.Autotaxin, Pruritus and Primary Biliary Cholangitis (PBC)

关键词：Autotaxin ; lysophosphatidylcholine ; cholestatic liver diseases ; pruritus ; autoimmunity

刊名：Autoimmunity Reviews

出版年：2016

7.Roles of specific lipid species in the cell and their molecular mechanism

作者：Tomohiro Kimura ; William Jennings ; Richard M. Epand ; ^{epand@mcmaster.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：Acc ; acetyl-CoA carboxylase ; ASM ; acid sphingomyelinase ; ATP ; adenosine triphosphate ; ATPase ; adenosine triphosphatase ; ATX ; autotaxin ; BMP ; bis(monoacylglycero)phosphate ; CDP ; cytidine diphosphate ; CL ; cardiolipin ; CNS ; central nervous system ; COPI ; coat protein I ; DAG ; diacylglycerol ; ER ; endoplasmic reticulum ; FRET ; fluorescence resonance energy transfer ; GPCR ; G protein coupled receptor ; Hsp ; heat shock protein ; IP3 ; inositol trisphosphate ; LHC II ; light harvesting complex II ; LPA ; lysophosp

刊名：Progress in Lipid Research

出版年：2016

8.The autotaxin-lysophosphatidic acid pathway in pathogenesis of rheumatoid arthritis

作者：Beatriz Orosa ; Samuel García ; Carmen Conde ; ^{Carmen.Conde.Muro@sergas.es" class="auth_mail" title="E-mail the corresponding author}

关键词：Autotaxin ; Experimental arthritis ; ibroblast‐like ; fibroblast like ; Inflammatory response ; Lysophosphatidic acid ; Rheumatoid arthritis

刊名：European Journal of Pharmacology

出版年：2015

9.Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma

作者：Mayuko Kondo^a ; Takeaki Ishizawa^c ; Kenichiro Enooku^a ; ^b ; Yasunori Tokuhara^b ; Ryunosuke Ohkawa^b ; Baasanjav Uranbileg^b ; Hayato Nakagawa^a ; Ryosuke Tateishi^a ; Haruhiko Yoshida^a ; Norihiro Kokudo^c ; Kazuhiko Koike^a ; Yutaka Yatomi^b ; Hitoshi Ikeda^a ; ^b ; ^{ikeda-1im@h.u-tokyo.ac.jp" class="auth_mail}

关键词：ATX ; autotaxin ; HCC ; hepatocellular carcinoma ; RFA ; radiofrequency ablation ; LPA ; lysophosphatidic acid ; APRI ; aspartate aminotransferase-to-platelet ratio index

刊名：Clinica Chimica Acta

出版年：10 June 2014

10.Decrease in circulating autotaxin by oral administration of prednisolone

作者：Hayakazu Sumida^a ; ^b ; ^{sumida-tky@umin.ac.jp} ; Kazuhiro Nakamura^c ; Keisuke Yanagida^a ; Ryunosuke Ohkawa^c ; Yoshihide Asano^b ; Takafumi Kadono^b ; Kunihiko Tamaki^b ; Koji Igarashi^d ; Junken Aoki^e ; Shinichi Sato^b ; Satoshi Ishii^a ; Takao Shimizu^a ; Yutaka Yatomi^c

关键词：Autotaxin (ATX) ; Lysophosphatidic acid (LPA) ; Lysophospholipase D (LysoPLD) ; Lysophospholipid ; Prednisolone (PSL)

刊名：Clinica Chimica Acta

出版年：2013

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