搜索页_CCR5+inhibitor

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在“Elsevier电子期刊”中，命中：123条，耗时：0.0129868 秒

在所有数据库中总计命中：183条

1.Steatosis induced CCL5 contributes to early-stage liver fibrosis in nonalcoholic fatty liver disease progress

作者：Bing-Hang Li^a ; ¹ ; Fang-Ping He^b ; ¹ ; Xin Yang^c ; Yuan-Wen Chen^a ; ^{drchenyuanwen@163.com} ; Jian-Gao Fan^a ; ^{fattyliver2004@126.com}

关键词：CCL5 ; chemokine (C-C motif) ligand 5 ; RANTES ; regulated upon activation normal T-cell expressed and secreted ; CCR5 ; C-C chemokine receptor type 5 ; NAFLD ; nonalcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; HFD ; high-fat-diet ; α-SMA ; alpha smooth muscle actin ; TGF-β ; transforming growth factor-β ; FFA ; free fatty acid ; MMP-2 ; matrix metalloproteinase-2 ; C/EBP-β ; CCAAT/enhancer-binding protein-β ; NF-κB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; XBP-1 ; X box

刊名：Translational Research

出版年：2017

2.The Selective Serotonin Reuptake Inhibitor Citalopram Decreases Human Immunodeficiency Virus Receptor and Coreceptor Expression in Immune Cells

作者：Jeffrey M. Greeson^a ; David R. Gettes^a ; Sergei Spitsin^e ; Benoit Dubé ; ^a ; Tami D. Benton^a ; ^f ; Kevin G. Lynch^a ; Steven D. Douglas^b ; ^e ; Dwight L. Evans^a ; ^c ; ^d ; ^{dlevans@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CCR5 ; CD4 ; CXCR4 ; Depression ; HIV ; SSRI

刊名：Biological Psychiatry

出版年：2016

3.Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy

作者：Ayako Hoshi^a ; Takeshi Sakamoto^a ; ^{sakamoto@josai.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Takayama^a ; Meiyan Xuan^a ; Mari Okazaki^a ; Tracy L. Hartman^b ; Robert W. Buckheit Jr.^b ; Christophe Pannecouque^c ; Mark Cushman^d ; ^{cushman@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ADAM ; alkenyldiarylmethane ; NNRTI ; non-nucleoside reverse transcriptase inhibitor ; RT ; reverse transcriptase ; HIV-1 ; human immunodeficiency virus type 1 ; AIDS ; acquired immune deficiency syndrome ; ART ; antiretroviral therapy ; NRTI ; nucleoside reverse transcriptase inhibitor ; PI ; protease inhibitor ; INI ; integrase inhibitors ; FI ; fusion inhibitor ; CCR5I ; CC chemokine receptor inhibitor ; dNTPs ; deoxynucleoside triphosphate ; AZT ; azidothymidine (zidovudine) ; EDCI ; 1-(3-dimethylaminopropyl)-3-ethylc

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris

作者：Fabrice Cerini^a ; Hubert Gaertner^a ; Knut Madden^b ; Ilya Tolstorukov^b ; ^c ; Scott Brown^d ; Bram Laukens^e ; ^f ; Nico Callewaert^e ; ^f ; Jay C. Harner^g ; Anna M. Oommen^g ; John T. Harms^g ; Anthony R. Sump^g ; Robert C. Sealock^g ; Dustin J. Peterson^g ; Scott K. Johnson^g ; Stephan B. Abramson^h ; Michael Meagher^g ; ¹ ; Robin Offordⁱ ; Oliver Hartley^a ; ⁱ ; ^{oliver.hartley@unige.ch" class="auth_mail" title="E-mail the corresponding author}

关键词：Pichia ; Yeast ; Process development ; Chemokine ; HIV ; Microbicide ; CCR5 ; 5P12-RANTES ; Biopharmaceutical ; cGMP

刊名：Protein Expression and Purification

出版年：2016

5.Evolution of coreceptor utilization to escape CCR5 antagonist therapy

作者：Jie Zhang^a ; Xiang Gao^a ; John Martin^b ; Bruce Rosa^b ; Zheng Chen^c ; ¹ ; Makedonka Mitreva^b ; Timothy Henrich^d ; ² ; Daniel Kuritzkes^d ; Lee Ratner^a ; ^{lratner@dom.wustl.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV/AIDS ; Tropism shift ; Coreceptor inhibitor ; Drug resistance

刊名：Virology

出版年：2016

6.The Janus kinase inhibitor ruxolitinib reduces HIV replication in human macrophages and ameliorates HIV encephalitis in a murine model

作者：Woldeab B. Haile^c ; ¹ ; Christina Gavegnano^a ; ^c ; ¹ ; Sijia Tao^a ; ^c ; Yong Jiang^a ; Raymond F. Schinazi^a ; ^c ; ^{rschina@emory.edu" class="auth_mail" title="E-mail the corresponding author} ; William R. Tyor^b ; ^c ; ^{wtyor@emory.edu" class="auth_mail" title="E-mail the corresponding author}

刊名：Neurobiology of Disease

出版年：2016

7.Mo1915 Genetic Ablation and Pharmacological Blockade of CCR5 by the anti-HIV Small Molecule Inhibitor Maraviroc Inhibits Leukocyte Trafficking and Protects Against Mucosal Inflammation in Murine Models Colitis

作者：Andrea Mencarelli ; Sabrina Cipriani ; Barbara Renga ; Daniela Francisci ; Franco Baldelli ; Luca Santucci ; Eleonora Distrutti ; Stefano Fiorucci

刊名：Gastroenterology

出版年：2016

8.Evaluating the appropriateness of dosing adjustments in the coadministration of maraviroc and CYP3A inhibitors: A literature review

作者：James Samuel Alcorn¹ ; ^{jsalcorn@ufl.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Maraviroc ; CCR5 antagonism ; Extended interval

刊名：HIV & AIDS Review

出版年：2016

9.Design, synthesis, and biological evaluation of novel piperidine-4-carboxamide derivatives as potent CCR5 inhibitors

作者：Suwen Hu ; Quan Gu ; Zhilong Wang ; Zhiyong Weng ; Yunrui Cai ; Xiaowu Dong ; Yongzhou Hu ; Tao Liu ; Xin Xie

关键词：CCR5 inhibitor ; Anti-HIV-1 agent ; Piperidine-4-carboxamide derivatives

刊名：European Journal of Medicinal Chemistry

出版年：7 January, 2014

10.A validated HPLC-MS method for quantification of the CCR5 inhibitor maraviroc in HIV+ human plasma

作者：Marco Simiele ; Lorena Baietto ; Alessio Audino ; Mauro Sciandra ; Stefano Bonora ; Giovanni Di Perri ; Antonio D&rsquo ; Avolio ; ^{antonio.davolio@unito.it" class="auth_mail}

关键词：Maraviroc ; HPLC-MS ; HIV ; Therapeutic drug monitoring ; Plasma

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：June, 2014

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