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在“Elsevier电子期刊”中，命中：2,149条，耗时：0.1759461 秒

在所有数据库中总计命中：3,374条

1.Inhibition of interleukin-5 induced false positive anti-drug antibody responses against mepolizumab through the use of a competitive blocking antibody

作者：Karen Liao ; ^{karen.x.liao@gsk.com} ; Erik Meyer ; Thomas N. Lee ; Amy Loercher ; Daniel Sikkema

关键词：Anti-drug antibodies (ADA) ; Immunogenicity ; IL-5 ; Mepolizumab

刊名：Journal of Immunological Methods

出版年：2017

2.Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response

作者：Jeroen Dekervel^* ; ¹ ; Ashenafi Bulle^* ; ^&dagger ; ; ¹ ; Petra Windmolders^* ; Diether Lambrechts^&Dagger ; ; ^§ ; ; Eric Van Cutsem^&dagger ; ; ^¶ ; ; Chris Verslype^* ; ^&dagger ; ; ^¶ ; ; Jos van Pelt^* ; ^&dagger ; ; ^¶ ; ; ^{Jos.vanpelt@kuleuven.be}

刊名：Translational Oncology

出版年：2017

3.Encapsulation of two different TLR ligands into liposomes confer protective immunity and prevent tumor development

作者：Banu Bayyurt^a ; Gizem Tincer^a ; ¹ ; Kubra Almacioglu^a ; Esin Alpdundar^b ; Mayda Gursel^b ; Ihsan Gursel^a ; ^{ihsangursel@bilkent.edu.tr}

关键词：TLR3 ; TLR9 ; Ligands ; Immunoadjuvant ; Liposomes ; Immune response ; Preventive cancer vaccine

刊名：Journal of Controlled Release

出版年：2017

4.Characterization of FcγRIIIA effector cells used in in vitro ADCC bioassay: Comparison of primary NK cells with engineered NK-92 and Jurkat T cells

作者：Yao-Te Hsieh^a ; ^{yao-te.hsieh@pfizer.com} ; Poonam Aggarwal^a ; ¹ ; ^{poonam.aggarwal@pfizer.com} ; David Cirelli^b ; Ling Gu^b ; Teresa Surowy^a ; Ned M. Mozier^a

关键词：mAbs ; monoclonal antibodies ; Fab ; fragment antigen-binding ; Fc ; fragment crystallizable ; NK cells ; natural killer cells ; ADCC ; antibody-dependent cell-mediated cytotoxicity ; MOA ; mechanisms of action ; NFAT ; nuclear factor of activated T cells ; T cells ; thymocyte cells ; IgG1 ; immunoglobulin G1 ; FcR ; Fc receptor ; IL-2 ; interleukin-2 ; ASN-297 ; asparagine-297 ; V-158 ; valine at amino acid 158 ; F-158 ; phenylalanine at amino acid 158 ; EGFR ; epidermal growth factor receptor ; AAF-Glo&trade ; alanyl-alany

刊名：Journal of Immunological Methods

出版年：2017

5.DNA damage induced by NADPH cytochrome P450 reductase-activated idarubicin in sensitive and multidrug resistant MCF7 breast cancer cells

作者：Wojciech Żwierełło^a ; ^b ; Agnieszka Maruszewska^a ; ^b ; Robert Nowak^a ; ^b ; ¹ ; Dorota Kostrzewa-Nowak^a ; ^b ; ² ; Jolanta Tarasiuk^a ; ^b ; ^{tarasiuk@univ.szczecin.pl}

关键词：Anthracycline antitumour drugs ; Idarubicin ; NADPH cytochrome P450 reductase ; Multidrug resistance ; DNA damage

刊名：Pharmacological Reports

出版年：2017

6.Cellular uptake of glucoheptoamidated poly(amidoamine) PAMAM G3 dendrimer with amide-conjugated biotin, a potential carrier of anticancer drugs

作者：Łukasz Uram^a ; ^{luram@prz.edu.pl} ; Magdalena Szuster^a ; Aleksandra Filipowicz^b ; Magdalena Zaręba^a ; Elżbieta Wałajtys-Rode^c ; Stanisław Wołowiec^d

关键词：PAMAM G3 dendrimer ; Biotin bioconjugate ; d-Glucoheptono-1 ; 4-lactone ; Synthesis ; Confocal microscopy ; Cellular uptake ; Anticancer vehicle ; In vitro ; Toxicity ; Normal and cancer cells

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

7.Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002

作者：Alexey Goltsov^a ; ^{a.goltsov@abertay.ac.uk} ; Ghassan Tashkandi^b ; ^{s1163633@exseed.ed.ac.uk} ; Simon P. Langdon^b ; ^{Simon.Langdon@ed.ac.uk} ; David J. Harrison^c ; ^{David.Harrison@st-andrews.ac.uk} ; James L. Bown^a ; ^d ; ^{j.bown@abertay.ac.uk}

关键词：Kinetic modelling ; PI3K ; mTOR1 ; PTEN ; Rapamycin ; BEZ235

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

8.Determination of inosine 5′-monophosphate dehydrogenase activity in red blood cells of thiopurine-treated patients using HPLC

作者：Audrey Beringer^a ; ^b ; Antony Citterio-Quentin^a ; ^b ; Rebeca Obenza Otero^a ; Clé ; mence Gustin^a ; ^b ; Rebecca Clarke^a ; ^c ; Jean-Paul Salvi^a ; Roselyne Boulieu^a ; ^b ; ^{roselyne.boulieu@univ-lyon1.fr}

关键词：6-MeMPN ; 6-methyl mercaptopurine nucleotides ; 6-MP ; 6-mercaptopurine ; 6-TGN ; 6-thioguanine nucleotides ; AZA ; azathioprine ; β-NAD ; β-nicotinamide adenine dinucleotide ; DTT ; dithiothreitol ; IBD ; inflammatory bowel disease ; IMP ; inosine 5&prime ; -monophosphate ; IMPDH ; inosine 5&prime ; -monophosphate dehydrogenase ; ITPA ; inosine triphosphate pyrophosphatase ; meTIMP ; methyl thioinisone 5&prime ; -monophosphate ; MPA ; mycophenolic acid ; RBCs ; red blood cells ; TPMT ; thiopurine S-methyltransferase ; XMP ; xant

刊名：Journal of Chromatography B

出版年：2017

9.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

10.The Evolution of Oncology Companion Diagnostics from Signal Transduction to Immuno-Oncology

作者：Nicholas C. Dracopoli¹ ; ^{ndracopo@its.jnj.com} ; Mark S. Boguski² ; ^{mark.boguski@precisionready.com}

关键词：immunotherapy ; precision medicine ; predictive biomarkers ; signal transduction inhibitors

刊名：Trends in Pharmacological Sciences

出版年：2017

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