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在“Elsevier电子期刊”中，命中：279条，耗时：0.0289869 秒

在所有数据库中总计命中：388条

1.PGE₂-EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease

作者：Vincent Maingret^a ; ^b ; Gaë ; l Barthet^a ; ^b ; Sé ; verine Deforges^a ; ^b ; Nan Jiang^a ; ^b ; Christophe Mulle^a ; ^b ; Thierry Amé ; dé ; e^a ; ^b ; ^{thierry.amedee@u-bordeaux.fr}

关键词：Alzheimer's disease ; Inflammation ; PGE2 ; Synaptic plasticity ; Hippocampus ; APP/PS1

刊名：Neurobiology of Aging

出版年：2017

2.The EP1/EP3 receptor agonist 17-pt-PGE₂ acts as an EP4 receptor agonist on endothelial barrier function and in a model of LPS-induced pulmonary inflammation

作者：Anna Theiler ^{anna.theiler@medunigraz.at} ; Viktoria Konya ^{viktoria.konya@medunigraz.at} ; Lisa Pasterk ^{lisa.pasterk@medunigraz.at} ; Jovana Maric ^{jovana.maric@medunigraz.at} ; Thomas Bä ; rnthaler ^{thomas.baernthaler@medunigraz.at} ; Ilse Lanz ^{ilse.lanz@medunigraz.at} ; Wolfgang Platzer ^{wolfgang.platzer@medunigraz.at} ; Rufina Schuligoi ^{rufina.schuligoi@medunigraz.at} ; Akos Heinemann ; ^{akos.heinemann@medunigraz.at}

关键词：17-pt-PGE2 ; 17-phenyl trinor prostaglandin E2 ; BAL ; bronchoalveolar lavage ; EP ; E-type prostanoid receptor ; HMVEC-L ; human pulmonary microvascular endothelial cells ; HUVEC ; human umbilical vein endothelial cells ; LPS ; lipopolysaccharide ; MMVEC-L ; murine pulmonary microvascular endothelial cells

刊名：Vascular Pharmacology

出版年：2016

3.Optimization of amide-based EP3 receptor antagonists

作者：Esther C.Y. Lee^a ; ^{esther.lee2@pfizer.com" class="auth_mail" title="E-mail the corresponding author} ; Kentaro Futatsugi^a ; Joel T. Arcari^c ; Kevin Bahnck^c ; Steven B. Coffey^c ; David R. Derksen^d ; Amit S. Kalgutkar^b ; Paula M. Loria^d ; Raman Sharma^d

关键词：EP3 receptor ; PGE2 ; GPCR ; LipE ; Metabolites ; P-gp ; Indazole

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

4.Regulation of arterial reactivity by concurrent signaling through the E-prostanoid receptor 3 and angiotensin receptor 1

作者：Maria P. Kraemer^b ; ^{maria.c.palazzo@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Hyehun Choi^d ; Jeff Reese^c ; Fred S. Lamb^d ; Richard M. Breyer^a ; ^b ; ^e

关键词：Prostaglandin E2 ; Angiotensin II ; EP3 receptor ; Vascular reactivity ; Pyk2 ; AT1 receptor

刊名：Vascular Pharmacology

出版年：2016

5.Selective suppression of the human aryl hydrocarbon receptor function can be mediated through binding interference at the C-terminal half of the receptor

作者：Lina Ren^b ; John D. Thompson^a ; Michael Cheung^a ; Katherine Ngo^a ; Sarah Sung^a ; Scott Leong^a ; William K. Chan^a ; ^{wchan@pacific.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AHR ; aryl hydrocarbon receptor ; ARNT ; aryl hydrocarbon receptor nuclear translocator ; 3MC ; 3-methylcholanthrene ; FICZ ; 6-formylindolo(3 ; 2-b)carbazole ; TCDD ; 237 ; 8-tetrachlorodibenzo-p-dioxin ; αNF ; α-naphthoflavone ; CH ; CH223191 ; BaP ; benzo[a]pyrene ; CYP ; cytochrome P450 ; DRE ; dioxin response element

刊名：Biochemical Pharmacology

出版年：2016

6.Promising Effects of a Novel EP2 and EP3 Receptor Dual Agonist, ONO-8055, on Neurogenic Underactive Bladder in a Rat Lumbar Canal Stenosis Model

作者：Noritoshi Sekido ; ^{nsekido@med.toho-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Kida ; Hiroko Mashimo ; Daisuke Wakamatsu ; Hiroki Okada ; Hidekazu Matsuya

关键词：urinary bladder ; underactive ; urinary bladder ; neurogenic ; spinal canal ; constriction ; pathological ; dinoprostone

刊名：The Journal of Urology

出版年：2016

7.PPARγ signaling and emerging opportunities for improved therapeutics

作者：Shuibang Wang ; ^{swang@cc.nih.gov" class="auth_mail" title="E-mail the corresponding author} ; Edward J. Dougherty ; Robert L. Danner ; ^{rdanner@nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：PPARγ ; peroxisome proliferator-activated receptor gamma ; TZD ; thiazolidinedione ; T2DM ; type 2 diabetes mellitus ; RGZ ; rosiglitazone ; 15d-PGJ2 ; 15-deoxy-D12 ; 14-prostanglandin J2 ; PGC-1α ; PPARγ co-activator-1α ; RXR ; retinoid X receptor ; PPRE ; peroxisome proliferator response element ; NO ; nitric oxide ; EP300 ; E1A binding protein p300 ; PTM ; post-translational modification ; BAT ; brown adipose tissue ; SAT ; subcutaneous white adipose tissue ; VAT ; visceral white adipose tissue ; GPR40 ; G protein-coupled

刊名：Pharmacological Research

出版年：2016

8.IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models

作者：Iris Martinez-Quetglas¹ ; Roser Pinyol¹ ; Daniel Dauch² ; Sara Torrecilla¹ ; Victoria Tovar¹ ; Agrin Moeini¹ ; Clara Alsinet¹ ; Anna Portela³ ; Leonardo Rodriguez-Carunchio¹ ; Manel Solé ; ¹ ; Amaia Lujambio⁴ ; ⁵ ; Augusto Villanueva⁴ ; ⁶ ; Swan Thung⁴ ; Manel Esteller³ ; ⁷ ; Lars Zender² ; ⁸ ; Josep M. Llovet¹ ; ⁴ ; ⁷ ; ^{jmllovet@clinic.cat}

关键词：Hepatocarcinogenesis ; IGF 1 Receptor ; Epi-Driver ; Therapeutic Target

刊名：Gastroenterology

出版年：2016

9.Discovery of highly potent dual EP₂ and EP₃ agonists with subtype selectivity

作者：Akihiro Kinoshita^a ; ^{ak.kinoshita@ono.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Masato Higashino^a ; Yoshiyuki Aratani^a ; Akito Kakuuchi^a ; Hidekazu Matsuya^b ; Kazuyuki Ohmoto^a ; ^{k.ohmoto@ono.co.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Prostaglandin ; EP2 receptor ; EP3 receptor ; Dual agonist ; Underactive bladder

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.Effects of orexin A on glucose metabolism in human hepatocellular carcinoma in vitro via PI3K/Akt/mTOR-dependent and -independent mechanism

作者：Yuanyuan Liu^a ; Yuyan Zhao^a ; ; Lei Guo^b ; ^{g572@sina.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Orexin A ; Orexin receptor 1 ; Glucose metabolism ; Hepatocellular carcinoma ; Akt ; mTOR

刊名：Molecular and Cellular Endocrinology

出版年：2016

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