搜索页_Extracellular receptor kinase (ERK)

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在“Elsevier电子期刊”中，命中：2,392条，耗时：0.0639744 秒

在所有数据库中总计命中：2,985条

1.Somatostatin receptor 5 is a prominent regulator of signaling pathways in cells with coexpression of Cannabinoid receptors 1

作者：Shenglong Zou ; Rishi K. Somvanshi ; Ujendra Kumar ; ^{ujendra.kumar@ubc.ca}

关键词：AD ; Alzheimer&rsquo ; s disease ; cAMP ; cyclic adenosine monophosphate ; CB1R ; Cannabinoid receptor 1 ; CNS ; central nervous system ; co-IP ; co-immunoprecipitation ; Cy3 ; cyanine 3 ; D2R ; dopamine receptor 2 ; ERK1/2 ; extracellular signal-regulated kinase 1/2 ; FITC ; fluorescein isothiocyanate ; FSK ; forskolin ; GPCR ; G protein-coupled receptor ; HA ; hemagglutinin ; hCB1R ; human cannabinoid receptor 1 ; HD ; Huntington&rsquo ; s disease ; hSSTR5 ; human somatostatin receptor 5 ; IBMX ; 3-isobutyl-1-methylxanthine ; PA

刊名：Neuroscience

出版年：2017

2.The σ1 receptor regulates accumulation of GM1 ganglioside-enriched autophagosomes in astrocytes

作者：Rika Kasahara^a ; Naoki Yamamoto^a ; ^b ; ^{na-yamam@hokuriku-u.ac.jp} ; Kenji Suzuki^c ; Kazuya Sobue^d

关键词：σ1R ; sigma (σ)-1 receptor ; Aβ ; amyloid β-protein ; AD ; alzheimer disease ; APP ; amyloid precursor protein ; CTX-HRP ; Horseradish peroxidase-cholera toxin B subunit ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DR ; dopamine receptor ; DRMs ; detergent-resistant membrane microdomains ; ERK ; extracellular signal-regulated kinase ; FBS ; fetal bovine serum ; GM1 ; GM1 ganglioside ; PBS ; phosphate-buffered saline ; PDMP ; (± ; )-threo-1-phenyl-2-decanoylamine-3-morpholino-1-propanol hydrochloride ; PF

刊名：Neuroscience

出版年：2017

3.Regulation of proteasome activity by P2Y₂ receptor underlies the neuroprotective effects of extracellular nucleotides

作者：Laura de Diego-Garcí ; a^a ; ^c ; Mercedes Ramí ; rez-Escudero^a ; Á ; lvaro Sebastiá ; n-Serrano^a ; ^c ; Juan Ignacio Diaz-Herná ; ndez^a ; ^d ; Jesú ; s Pintor^b ; José ; J. Lucas^d ; ^e ; Miguel Dí ; az-Herná ; ndez^a ; ^c ; ^{migueldiaz@ucm.es}

关键词：UPS ; Ubiquitin-Proteasome System ; P2Y2R ; P2Y2 receptor ; IP3 ; inositol 14 ; 5-trisphosphate ; MEK1/2 ; MAP kinase kinases ; ERK ; extracellular signal-regulated kinase ; PKC ; protein kinase C ; PKA ; protein kinase A ; PI3K ; inositol 14 ; 5-trisphosphate 3-kinases ; MAPK/ERK ; mitogen-activated protein kinases ; GFP ; green fluorescent protein ; YFP ; yellow fluorescent protein ; ATP ; adenosine triphosphate ; UTP ; uridine triphosphate ; PPADS ; pyridoxalphosphate-6-azophenyl-2&prime ; 4&prime ; -disulfonic acid ; Up4U

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

4.A Highly Diverse and Functional Naïve Ubiquitin Variant Library for Generation of Intracellular Affinity Reagents

作者：Isabel Leung¹ ; ² ; Nick Jarvik² ; Sachdev S. Sidhu¹ ; ² ; ^{sachdev.sidhu@utoronto.ca}

关键词：Ubv ; ubiquitin variant ; Ub ; ubiquitin ; wt ; wild-type ; EGFR ; epidermal growth factor receptor ; EGF ; epidermal growth factor ; Her3 ; human epidermal growth factor receptor 3 ; NRG ; neuregulin ; Grb2 ; growth factor receptor-bound protein 2 ; GST ; glutathione S-transferase ; SPR ; surface plasmon resonance ; IP ; immunoprecipitation ; Grb2-SH2 ; Grb2 SH2 domain ; p-Tyr ; phospho-tyrosine ; pERK ; phosphorylated ERK ; pMEK ; phosphorylated MEK ; ERK ; extracellular signal-regulated kinase ; MEK ; MAPK/ERK kinase

刊名：Journal of Molecular Biology

出版年：2017

5.Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

作者：Mattia Volta ; ^{mattia.volta@eurac.edu} ; Alexandros A. Lavdas ; Julia Obergasteiger ; Christa Ü ; berbacher ; Anne Picard ; Peter P. Pramstaller ; Andrew A. Hicks ; Corrado Corti ; ^{corrado.corti@eurac.edu}

关键词：aSyn ; Alpha-synuclein ; PD ; Parkinson's disease ; PLCβ1 ; phospholipase Cβ1 ; PI(4 ; 5)P2 ; phosphoinositide-4 ; 5-bisphosphate ; Gq-PCRs ; Gq protein-coupled receptors ; IP3 ; inositol-14 ; 5-trisphosphate ; DAG ; diacylglycerol ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinase ; WT ; wild-type ; ERK1/2 ; extracellular-signal regulated kinase 1/2 ; 5-HT ; serotonin ; (CHO) ; Chinese hamster ovary cells ; FBS ; fetal bovine serum ; AP-1 ; activator protein-1 ; RT ; room temperature ; 5-HT ; serotonin ; SERCA ; sarc

刊名：Cellular Signalling

出版年：2017

6.Pneumococcal DnaJ modulates dendritic cell-mediated Th1 and Th17 immune responses through Toll-like receptor 4 signaling pathway

作者：Yingying Wu^a ; ^b ; ¹ ; Jingjing Cui^a ; ¹ ; Xuemei Zhang^a ; Song Gao^a ; Feng Ma^a ; Hua Yao^a ; Xiaoyu Sun^a ; Yujuan He^a ; Yibing Yin^a ; Wenchun Xu^a ; ^{xuwen0303@126.com} ; ^{xuwen0303@126.com}

关键词：DC ; dendritic cell ; APCs ; antigen presenting cells ; DnaJ/HSP40 ; heat shock proteins 40 ; MAPKs ; mitogen-activated protein kinases ; NF-κB ; nuclear factor-kappa B ; PI3K ; Phosphatidyl Inositol 3-kinase ; Akt ; serine/threonine kinase ; PAMPs ; pathogen-associated molecular patterns ; PRRs ; pattern recognition receptors ; ERK ; extracellular signal-regulated kinases ; JNK ; c-jun N-terminal kinase ; PGN ; Peptidoglycan ; LPS ; lipopolysaccharide

刊名：Immunobiology

出版年：2017

7.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

8.Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein

作者：Yeomoon Sim^a ; Gunhyuk Park^a ; Hyeyoon Eo^b ; Eugene Huh^b ; ^c ; Pil Sung Gu^b ; Seon-Pyo Hong^b ; Youngmi Kim Pak^d ; Myung Sook Oh^a ; ^b ; ^{msohok@khu.ac.kr}

关键词：6-OHDA ; 6-hydroxydopamine ; DAT ; dopamine transporter ; ERK ; extracellular signal-regulated kinase ; HPLC ; high-performance liquid chromatography ; MABH ; herbal extract combination of Bupleuri Radix ; Moutan Cortex Radicis and Angelica Dahuricae Radix ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; Nurr1 ; nuclear receptor-related 1 protein ; PBS ; phosphate-buffered saline ; PD ; Parkinson&rsquo ; s disease ; ROP ; ropinirole ; SNpc ; substantia nigra pars compacta ; ST ; striatum ; TH ; tyrosine hydroxylase

刊名：Neuroscience

出版年：2017

9.The GABA_B positive allosteric modulators CGP7930 and GS39783 stimulate ERK1/2 signalling in cells lacking functional GABA_B receptors

作者：Maria C. Olianas ; ^{molianas@unica.it} ; Simona Dedoni ; Pierluigi Onali

关键词：CGP7930 (PubChem CID ; 5024764) ; GS39783 (PubChem CID ; 6604928) ; (-)-baclofen (PubChem CID ; 44602) ; SKF97541 (PubChem CID ; 5230) ; CGP55845 (PubChem CID ; 5311042) ; CGP54626 (PubChem CID ; 197584) ; phorbol 12-myristate 13 acetate (PubChem CID ; 27924) ; Go 6850 (PubChem CID ; 2396) ; 5Z-7-oxozeaenol (PubChem CID ; 9863776) ; GW5074 (PubChem CID ; 5924208)

刊名：European Journal of Pharmacology

出版年：2017

10.Chemerin-induced arterial contraction is G_i- and calcium-dependent

作者：David J. Ferland ; ^{ferlandd@msu.edu} ; Emma S. Darios ; Richard R. Neubig ; Benita Sjö ; gren ; Nguyen Truong ; Rosa Torres ; Thomas S. Dexheimer ; Janice M. Thompson ; Stephanie W. Watts

关键词：Akt ; protein kinase B ; ANG II ; angiotensin II ; CaM ; calmodulin ; CCRL2 ; chemokine (CC motif) receptor-like 2 ; CMKLR1 ; chemokine-like receptor 1 ; Erk MAPK ; extracellular signal-regulated kinase mitogen activated protein kinase ; GAP ; GTPase activating protein ; GEF ; guanine nucleotide exchange factor ; GPR1 ; G protein-coupled receptor 1 ; MLC ; myosin light-chain ; MLCK ; myosin light-chain kinase ; MLCP ; myosin light-chain phosphatase ; PD098059 ; 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one ; PE ; phenyleph

刊名：Vascular Pharmacology

出版年：2017

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