搜索页_activity relationships (SAR)

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在“Elsevier电子期刊”中，命中：1,142条，耗时：0.1049571 秒

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1.Structure-activity relationships of diverse xanthones against multidrug resistant human tumor cells

作者：Qiwen Wang^a ; Chenyao Ma^a ; Yun Ma^a ; Xiang Li^a ; ^c ; ^{lixiang_8182@163.com} ; Yong Chen^a ; ^{achenyongmail@163.com} ; Jianwei Chen^a ; ^b

关键词：Xanthone ; Cytotoxic activity ; Multidrug resistant ; Structure-activity relationships

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Antiproliferative activity and SARs of caffeic acid esters with mono-substituted phenylethanols moiety

作者：Jin Xie ; Fengzhi Yang ; Man Zhang ; Celine Lam ; Yixue Qiao ; Jia Xiao ; Dongdong Zhang ; Yuxuan Ge ; Lei Fu ; ^{leifu@sjtu.edu.cn} ; Dongsheng Xie ; ^{dshxie@sjtu.edu.cn}

关键词：Caffeic acid esters ; CAPE derivatives ; Antiproliferative activity ; Structure-activity relationships

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.The anti-proliferative activity of novel 4H-benzo[h]chromenes, 7H-benzo[h]-chromeno[2,3-d]pyrimidines and the structure-activity relationships of the 2-, 3-positions and fused rings at the 2, 3-positions

作者：Ahmed M. El-Agrody^a ; ^b ; ^{elagrody_am@yahoo.com} ; Ahmed H. Halawa^a ; Ahmed M. Fouda^b ; Al-Anood M. Al-Dies^b

关键词：4H-Benzo[h]chromenes ; 7H-Benzo[h]chromeno[2 ; 3-d]pyrimidines ; Antitumor ; SAR

刊名：Journal of Saudi Chemical Society

出版年：2017

4.Synthesis of novel substituted pyrimidine derivatives bearing a sulfamide group and their in vitro cancer growth inhibition activity

作者：Carole-Anne Lefebvre^a ; ¹ ; Elsa Forcellini^a ; ¹ ; Sophie Boutin^a ; Marie-France Cô ; té ; ^b ; René ; C.-Gaudreault^b ; ^c ; Patrick Mathieu^d ; Patrick Lagü ; e^e ; Jean-Franç ; ois Paquin^a ; ^{jean-francois.paquin@chm.ulaval.ca}

关键词：Pyrimidine ; Sulfamide ; Anticancer activities ; Structure-activity relationships (SARs) ; Growth inhibition

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

5.Imidazopyridine-fused [1,3]-diazepinones part 2: Structure-activity relationships and antiproliferative activity against melanoma cells

作者：Virginie Bellet ; Laure Lichon ; Dominique P. Arama ; Audrey Gallud ; Vincent Lisowski ; Ludovic T. Maillard ; Marcel Garcia ; Jean Martinez ; Nicolas Masurier ; ^{nicolas.masurier@umontpellier.fr}

关键词：Imidazo[1 ; 2-a]pyridine ; Polyfused heterocycles ; Diazepinones ; Antitumor activity ; Melanoma

刊名：European Journal of Medicinal Chemistry

出版年：2017

6.A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A

作者：William A. Harrell Jr.^a ; ^d ; Rebecca C. Vieira^a ; ^e ; Susan M. Ensel^b ; Vicki Montgomery^a ; Rebecca Guernieri^a ; Vanessa S. Eccard^a ; ^f ; Yvette Campbell^a ; Virginia Roxas-Duncan^a ; ^g ; John H. Cardellina II^a ; ^h ; Robert P. Webb^a ; ^{robert.p.webb6.civ@mail.mil} ; Leonard A. Smith^c

关键词：BoNTs ; botulinum neurotoxins ; BoNT/A ; botulinum neurotoxin serotype A ; HC ; heavy chain ; LC ; light chain ; SNARE ; soluble N-ethylmaleimide-sensitive factor attachment protein receptor ; SNAP-25 ; 25 ; kDa synaptosomal-associated protein ; BIG-IV ; Botulism Immune Globulin Intravenous (Human) ; SAR ; structure-activity relationship ; IC50 ; 50% inhibitory concentration ; MPNHDA ; mouse phrenic nerve hemidiaphragm assay

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Structure-activity relationships of benzothiazole GPR35 antagonists

作者：Manahil M. Abdalhameed^a ; Pingwei Zhao^b ; Dow P. Hurst^a ; Patricia H. Reggio^a ; ^{phreggio@uncg.edu} ; Mary E. Abood^b ; ^{mabood@temple.edu} ; Mitchell P. Croatt^a ; ^{mpcroatt@uncg.edu}

关键词：GPR35 ; Antagonist ; G protein-coupled receptor ; Benzothiazole ; SAR

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

8.Progress in the development of β-lactams as N-Acylethanolamine Acid Amidase (NAAA) inhibitors: Synthesis and SAR study of new, potent N-O-substituted derivatives

作者：R. Petracca^a ; S. Ponzano^a ; S.M. Bertozzi^a ; O. Sasso^a ; D. Piomelli^a ; ^b ; T. Bandiera^a ; F. Bertozzi^a ; ^{fabio.bertozzi@iit.it}

关键词：N-Acylethanolamine acid amidase ; Cysteine hydrolase ; N-O-Substituted β-lactams ; Inhibitors ; Structure&ndash ; activity relationships (SAR)

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.Structure-activity relationships on the study of β-galactosidase folding/unfolding due to interactions with immobilization additives: Triton X-100 and ethanol

作者：Dayana Soto^a ; Sindy Escobar^a ; Fanny Guzmá ; n^b ; Constanza Cá ; rdenas^b ; Claudia Bernal^c ; Monica Mesa^a ; ^{monica.mesa@udea.edu.com} ; ^{mesacad@gmail.com}

关键词：BgaC ; β&ndash ; galactosidase from Bacillus circulans ; CD ; Circular Dichroism ; DSC ; Differential Scanning Calorimetry ; FTIR ; Infrared spectroscopy

刊名：International Journal of Biological Macromolecules

出版年：2017

10.Silver(I) complexes of methyl xanthate against human adenocarcinoma breast cancer cells

作者：Christina N. Banti^a ; ^{cbanti@cc.uoi.gr} ; Nikolaos Kourkoumelis^b ; Constantinos G. Tsiafoulis^c ; Stavroula Skoulika^d ; Sotiris K. Hadjikakou^a ; ^{shadjika@uoi.gr}

关键词：Bioinorganic chemistry ; Silver(I) complexes ; Xanthates ; Cytotoxic activity ; Structural activity relationship

刊名：Polyhedron

出版年：2017

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