作者：Radhika S. Joshi^a ; ^{radhikasj@ncbs.res.in} ; Rolen Quadros^a ; Michael Drumm^a ; ^b ; Rupasri Ain^a ; ¹ ; Mitradas M. Panicker^a ; ^{panic@ncbs.res.in}

关键词：5-HT2A ; Clozapine ; Environmental novelty ; Knockout

刊名：European Neuropsychopharmacology

出版年：2017

作者：Viviane Muniz da Silva Fragoso^a ; ^{viviane.fragoso@ioc.fiocruz.br" class="auth_mail" title="E-mail the corresponding author} ; Luanda Yanaan Hoppe^a ; ^{luanda.hoope@ioc.fiocruz.br" class="auth_mail" title="E-mail the corresponding author} ; Tâ ; nia Cremonini de Araú ; jo-Jorge^a ; ^{taniaaj@ioc.fiocruz.br" class="auth_mail" title="E-mail the corresponding author} ; Marcos José ; de Azevedo^a ; ^{socram@ioc.fiocruz.br" class="auth_mail" title="E-mail the corresponding author} ; Jerô ; nimo Diego de Souza Campos^b ; ^{jeron.diego@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Cé ; lia Martins Cortez^c ; ^{ccortezs@ime.uerj.br" class="auth_mail" title="E-mail the corresponding author} ; Gabriel Melo de Oliveira^b ; ^{gmoliveira@ioc.fiocruz.br" class="auth_mail" title="E-mail the corresponding author}

关键词：MSA ; model of spontaneous aggression ; AgR ; aggressive mice ; TST ; tail suspension test ; OFT ; open field test ; AgD ; subordinate mice ; PAB ; pattern of aggressive behavior ; BTT ; before treatment ; LDT ; last day of treatment ; PTD ; pharmacological treatment discontinuation ; Low ; hypoactivity ; with low mobility ; High ; hyperactivity ; with high mobility ; Med ; medium mobility

刊名：Behavioural Brain Research

出版年：2016

作者：M.L. Oca^a ; L. Rubio^a ; M.C. Ortiz^a ; ^{mcortiz@ubu.es" class="auth_mail" title="E-mail the corresponding author} ; L.A. Sarabia^b ; I. Garcí ; a^c

关键词：ICH ; International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use ; IUPAC ; International Union of Pure and Applied Chemistry ; LC/MS&ndash ; MS ; Liquid chromatography coupled to tandem mass spectrometry ; XYL ; Xylazine ; AZA ; Azaperone ; PROP ; Propionylpromazine ; CHLOR ; Chlorpromazine ; HALO ; Haloperidol ; AZOL ; Azaperol ; CAR ; Carazolol ; SPE ; Solid-phase extraction ; MRL ; Maximum residue limit ; IS ; Internal standard ; APCI ; Atmospheric pressure chemi

刊名：Chemometrics and Intelligent Laboratory Systems

出版年：2016

作者：Herbert M. Himmel ; ^{herbert.himmel@bayer.com" class="auth_mail" title="E-mail the corresponding author} ; Michael Hoffmann

关键词：Blood pressure ; Central nervous system ; d-Amphetamine ; &ldquo ; Induced hyperactivity&rdquo ; method ; Locomotor activity ; (+)-MK-801 ; NMDA antagonist ; Off-target activity ; Rat ; Reference compounds

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

作者：Anne Marie Hernier ; Christelle Froger-Collé ; aux ; ^{cfroger@porsolt.com" class="auth_mail" title="E-mail the corresponding author} ; Vincent Castagné

关键词：Behavioral methods ; Cognition ; Diazepam ; Haloperidol ; MK-801 ; Nicotine ; Scopolamine ; Safety pharmacology ; Rodents

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

作者：Izabela Sadowska-Bartosz^a ; ^{isadowska@poczta.fm" class="auth_mail" title="E-mail the corresponding author} ; Sabina Galiniak^a ; Grzegorz Bartosz^a ; ^b ; Mariusz Zuberek^b ; Agnieszka Grzelak^b ; Anna Dietrich-Muszalska^c

关键词：ABTS* ; 2 ; 2&prime ; -azinobis(3-ethylbenzthiazoline-6-sulfonic acid) radical ; AAPH ; 2 ; 2&prime ; -azobis(2-amidinopropane) dihydrochloride ; AAPs ; atypical antipsychotics ; ARI ; aripiprazole ; BSA ; bovine serum albumin ; CLZ ; clozapine ; DHR123 ; dihydrorhodamine 123 ; DMEM ; Dulbecco's Modified Eagle Medium ; DMSO ; dimethylsulfoxide ; DPPH* ; 2 ; 2-diphenyl-1-picrylhydrazyl free radical ; FRAP ; The Ferric Reducing Antioxidant Potential ; HAL ; haloperidol ; HOCl ; hypochlorous acid ; HSA ; human serum albumin ; N2A ; mous

刊名：Schizophrenia Research

出版年：2016

作者：Emily R. Pfeiffer ; ^{epfeiffer@valasciences.com" class="auth_mail" title="E-mail the corresponding author} ; Raquel Vega ; Patrick M. McDonough ; Jeffrey H. Price ; Ross Whittaker

关键词：Fluo 4AM (PubChem CID ; 4060965) ; Cisapride (PubChem CID ; 2769) ; Dofetilide (PubChem CID ; 71329) ; Droperidol (PubChem CID ; 3168) ; Haloperidol (PubChem CID ; 3559) ; Pimozide (PubChem CID ; 16362) ; Quinidine (PubChem CID ; 441074) ; Sematilide (PubChem CID ; 58505) ; Sotalol (PubChem CID ; 66245) ; Thioridazine (PubChem CID ; 5452)

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

作者：Pouria Jandaghi¹ ; ² ; ³ ; Hamed S. Najafabadi² ; ³ ; Andrea S. Bauer¹ ; Andreas I. Papadakis⁴ ; ⁵ ; Matteo Fassan⁶ ; Anita Hall⁵ ; ⁷ ; Anie Monast⁵ ; Magnus von Knebel Doeberitz⁸ ; John P. Neoptolemos⁹ ; Eithne Costello⁹ ; William Greenhalf⁹ ; Aldo Scarpa⁶ ; ¹⁰ ; Bence Sipos¹¹ ; Daniel Auld² ; ³ ; Mark Lathrop² ; ³ ; Morag Park⁴ ; ⁵ ; ¹² ; ¹³ ; Markus W. Bü ; chler¹⁴ ; Oliver Strobel¹⁴ ; Thilo Hackert¹⁴ ; Nathalia A. Giese¹⁴ ; George Zogopoulos⁵ ; ⁷ ; Veena Sangwan⁵ ; ¹³ ; Sidong Huang⁴ ; ⁵ ; Yasser Riazalhosseini² ; ³ ; ^{Yasser.riazalhosseini@mcgill.ca} ; Jö ; rg D. Hoheisel¹

关键词：TMA ; Unfolded Protein Response ; Drug Repositioning ; Pancreas

刊名：Gastroenterology

出版年：2016

作者：Haoyu Zeng ; ^{haoyu.zeng@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Maria I. Roman ; Edward Lis ; Armando Lagrutta ; Frederick Sannajust

关键词：hiPSC-CM ; Preclinical cardiac safety ; Ca2  ; +-transient

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

作者：Lexy N. Pezarro Schimmel^a ; Tomek J. Banasikowski^a ; Emily R. Hawken^a ; ^b ; Eric C. Dumont^a ; ^b ; ^c ; Richard J. Beninger^a ; ^c ; ^d ; ^{Beninger@queensu.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：ANOVA ; analysis of variance ; BSA ; bovine serum albumin ; DA ; dopamine ; DAB ; diaminobenzidine ; dd H20 ; double distilled water ; DLS ; dorsolateral striatum ; DMS ; dorsomedial striatum ; GABA ; 纬-aminobutyric acid ; lHab ; lateral habenula ; NAc ; nucleus accumbens ; NAcC ; nucleus accumbens core ; NaCl ; sodium chloride ; NAcS ; nucleus accumbens shell ; PBS ; phosphate buffered saline ; TB ; trizmabase ; TBS ; trizmabase sodium chloride ; TBS-T ; trizmabase sodium chloride and Triton X-100 ; vHipp ; ventral hippocampus

刊名：Behavioural Brain Research

出版年：2015