作者：Yoichiro Otaki^a ; Tetsu Watanabe^a ; ^{tewatana@med.id.yamagata-u.ac.jp} ; Daisuke Kinoshita^a ; Miyuki Yokoyama^a ; Tetsuya Takahashi^a ; Taku Toshima^a ; Takayuki Sugai^a ; Takayo Murase^b ; Takashi Nakamura^c ; Satoshi Nishiyama^a ; Hiroki Takahashi^a ; Takanori Arimoto^a ; Tetsuro Shishido^a ; Takuya Miyamoto^a ; Isao Kubota^a

关键词：Xanthine oxidoreductase ; Uric acid ; Heart failure ; Cardiac prognosis

刊名：International Journal of Cardiology

出版年：2017

作者：K.E. Danielyan^a ; ^b ; ^{Kristine_danielyan@biochem.sci.am} ; A.A. Simonyan^a

关键词：Oxidative stress ; Xanthine oxidase ; B6 ; Allopurinol ; Brain ; Neuronal cell culture

刊名：Biomedicine & Pharmacotherapy

出版年：2017

作者：Takayo Murase ; ^{ta_murase@skk-net.com" class="auth_mail" title="E-mail the corresponding author} ; Mai Nampei ; Mitsuru Oka ; Atsushi Miyachi ; Takashi Nakamura

关键词：ALT ; alanine transaminase ; AST ; aspartate transaminase ; BUN ; blood urea nitrogen ; Cre ; creatinine ; CV ; coefficient of variation ; FL ; fluorescence ; HX ; hypoxanthine ; ISTD ; internal standard ; IXP ; isoxanthopterin ; LC ; liquid chromatography ; LLOQ ; lower limit of quantification ; RE ; relative error ; T-cho ; total cholesterol ; TQMS ; triple quadrupole mass spectrometry ; UA ; uric acid ; UPLC ; ultra-performance liquid chromatography ; UV ; ultraviolet ; X ; xanthine ; XDH ; xanthine dehydrogenase ; XO ; xanthine o

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

作者：Jeong Uk Song^a ; ^b ; Jae Wan Jang^b ; Tae Hun Kim^b ; Heuisul Park^b ; Wan Su Park^b ; Sang-Hun Jung^a ; ^{jungshh@cnu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Geun Tae Kim^b ; ^{gtakim@lgls.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Xanthine oxidase inhibitors ; Hyperuricemia ; Molecular modeling ; Structure&ndash ; activity relationship ; 2-(Indol-2-yl)thiazole

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

作者：Takayo Murase^a ; ^{ta_murase@skk-net.com" class="auth_mail" title="E-mail the corresponding author} ; Mai Nampei^b ; Mitsuru Oka^c ; Naoki Ashizawa^d ; Koji Matsumoto^d ; Atsushi Miyachi^a ; Takashi Nakamura^b

关键词：XOR ; xanthine oxidoreductase ; LC ; liquid chromatography ; HRMS ; high-resolution mass spectrometry ; UA ; uric acid ; UV ; ultraviolet ; FL ; fluorescence ; XDH ; xanthine dehydrogenase ; XO ; xanthine oxidase ; IXP ; isoxanthopterin ; ISTD ; internal standard ; LLOQ ; lower limit of quantification ; CV ; coefficient of variation ; RE ; relative error ; UPLC ; ultra-performance liquid chromatography ; TBS ; Tris&ndash ; buffered saline

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

作者：Shivraj Hariram Nile ; Eun Young Ko ; Doo Hwan Kim ; Young-Soo Keum ; ^{rational@konkuk.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Ferulic acid ; Gallic acid ; Xanthine oxidase ; Cyclooxygenase ; SAR ; Gout

刊名：Revista Brasileira de Farmacognosia

出版年：2016

作者：Emily Hofmann^a ; Jonathan Webster^a ; Thuy Do^a ; Reid Kline^a ; Lindsey Snider^a ; Quintin Hauser^a ; Grace Higginbottom^b ; Austin Campbell^b ; Lili Ma^a ; Stefan Paula^a ; ^b ; ^c ; ^{paulas@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Aβ ; β-amyloid peptide ; CAPE ; caffeic acid phenethylester ; DMF ; dimethylformamide ; DPPH ; 2 ; 2-diphenyl-1-picrylhydrazyl ; EGTA ; ethylene glycol tetraacetic acid ; HRMS ; high resolution mass spectrometry ; MOMO ; methoxymethoxy ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; NADPH ; nicotinamide adenine dinucleotide ; PBS ; phosphate-buffered saline ; ROS ; reactive oxygen species ; XO ; xanthine oxidase

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

作者：Marili V.N. Rodrigues^a ; ^b ; Alexandre F. Barbosa^c ; Jú ; lia F. da Silva^c ; Deborah A. dos Santos^c ; Kenia L. Vanzolini^b ; Marcela C. de Moraes^b ; ^d ; Arlene G. Corrê ; a^c ; ^{agcorrea@ufscar.br" class="auth_mail" title="E-mail the corresponding author} ; Quezia B. Cass^b ; ^{quezia@pq.cnpq.br" class="auth_mail" title="E-mail the corresponding author}

关键词：Xanthine oxidase inhibitor ; 9-Deazaguanine ; On-flow bidimensional liquid chromatography ; Non-competitive inhibition ; Allopurinol ; Green synthesis ; Microwave

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

作者：Jun Fang^a ; ^b ; ^c ; ¹ ; ^{fangjun@ph.sojo-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Hongzhuan Yin^a ; ^d ; ¹ ; Long Liao^a ; ^e ; Haibo Qin^a ; ^e ; Fumiko Ueda^a ; ^b ; Kyoko Uemura^a ; ^b ; Kanami Eguchi^a ; ^b ; Gahininath Y. Bharate^a ; ^f ; Hiroshi Maeda^a ; ^b ; ^{hirmaeda@ph.sojo-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Inflammatory bowel disease ; Reactive oxygen species ; Inflammation ; Xanthine oxidase inhibitor ; AHPP ; Micelle drug

刊名：Journal of Controlled Release

出版年：2016

作者：Wei-Jia Chen^a ; Yi Wu^a ; Xin Zhao^a ; Shu Liu^b ; ^{mslab20@ciac.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Feng-Rui Song^b ; Zhong-Ying Liu^a ; ^{Liuzy@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Zhi-Qiang Liu^b

关键词：Gout ; Inflammation ; Human umbilical vein endothelial cells ; Xanthine oxidase ; UPLC&ndash ; MS/MS

刊名：Chinese Chemical Letters

出版年：2016