作者：Thomas K. Eigentler^a ; ¹ ; ^{thomas.eigentler@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author} ; Jessica C. Hassel^b ; ¹ ; ^{jessica.hassel@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Carola Berking^c ; ^{carola.berking@med.uni-muenchen.de" class="auth_mail" title="E-mail the corresponding author} ; Jens Aberle^d ; ^{aberle@uke.de" class="auth_mail" title="E-mail the corresponding author} ; Oliver Bachmann^e ; ^{bachmann.oliver@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author} ; Viktor Grü ; nwald^f ; ^{Gruenwald.Victor@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author} ; Katharina C. Kä ; hler^g ; ^{kckaehler@dermatology.uni-kiel.de" class="auth_mail" title="E-mail the corresponding author} ; Carmen Loquai^h ; ^{Carmen.Loquai@unimedizin-mainz.de" class="auth_mail" title="E-mail the corresponding author} ; Niels Reinmuthⁱ ; ^{n.reinmuth@lungenclinic.de" class="auth_mail" title="E-mail the corresponding author} ; Martin Steins^j ; ^{martin.steins@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Lisa Zimmer^k ; ^{lisa.zimmer@uk-essen.de" class="auth_mail" title="E-mail the corresponding author} ; Anna Sendl^l ; ^{anna.sendl@bms.com" class="auth_mail" title="E-mail the corresponding author} ; Ralf Gutzmer^m ; ^{gutzmer.ralf@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Immunotherapy ; PD-1 ; Nivolumab ; Pembrolizumab ; Adverse drug reaction ; Immune-related adverse events

刊名：Cancer Treatment Reviews

出版年：2016

作者：Dirk Schadendorf^a ; ^{dirk.schadendorf@uk-essen.de" class="auth_mail" title="E-mail the corresponding author} ; Reinhard Dummer^b ; ^{Reinhard.Dummer@usz.ch" class="auth_mail" title="E-mail the corresponding author} ; Axel Hauschild^c ; ^{ahauschild@dermatology.uni-kiel.de" class="auth_mail" title="E-mail the corresponding author} ; Caroline Robert^d ; ^{Caroline.Robert@gustaveroussyr.fr" class="auth_mail" title="E-mail the corresponding author} ; Omid Hamid^e ; ^{ohamid@theangelesclinic.org" class="auth_mail" title="E-mail the corresponding author} ; Adil Daud^f ; ^{Adil.Daud@ucsf.edu" class="auth_mail" title="E-mail the corresponding author} ; Alfons van den Eertwegh^g ; ^{vandeneertwegh@VUMC.nl" class="auth_mail" title="E-mail the corresponding author} ; Lee Cranmer^h ; ^{lcranmer@uacc.arizona.edu" class="auth_mail" title="E-mail the corresponding author} ; Steven O'Dayⁱ ; ^{stevenjoday@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Igor Puzanov^j ; ^{igor.puzanov@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author} ; Jacob Schachter^k ; ^{Jacob.Schachter@sheba.health.gov.il" class="auth_mail" title="E-mail the corresponding author} ; Christian Blank^l ; ^{c.blank@nki.nl" class="auth_mail" title="E-mail the corresponding author} ; April Salama^m ; ^{april.salama@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Carmen Loquaiⁿ ; ^{carmen.loquai@unimedizin-mainz.de" class="auth_mail" title="E-mail the corresponding author} ; Janice M. Mehnert^o ; ^{mehnerja@cinj.rutgers.edu" class="auth_mail" title="E-mail the corresponding author} ; Darcy Hille^p ; ^{darcy_hille@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Scot Ebbinghaus^p ; ^{scot_ebbinghaus@merck.com" class="auth_mail" title="E-mail the corresponding author} ; S. Peter Kang^p ; ^{s.peter.kang@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Wei Zhou^p ; ^{wei.zhou2@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Antoni Ribas^q ; ^{aribas@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Pembrolizumab ; Patient-reported outcomes ; Health-related quality of life ; KEYNOTE-002 ; Advanced melanoma ; Ipilimumab-refractory melanoma ; Chemotherapy ; EORTC QLQ-C30

刊名：European Journal of Cancer

出版年：2016

作者：Rudolf Kä ; fer ; Svetlana Usanova ; Evelyn Montermann ; Carmen Loquai ; Angelika B. Reske-Kunz ; Matthias Bros ; ^{mbros@uni-mainz.de" class="auth_mail" title="E-mail the corresponding author}

关键词：WNT ; β-catenin ; Dendritic cells ; Costimulators ; T cells

刊名：International Immunopharmacology

出版年：2016

作者：Carmen S. Metzger ; Dimitrios Koutsimpelas ; Juergen Brieger ; ^{juergen.brieger@unimedizin-mainz.de" class="auth_mail" title="E-mail the corresponding author}

关键词：3&prime ; -UTR ; 3&prime ; -untranslated region ; 5&prime ; -UTR ; 5&prime ; -untranslated region ; ARE ; AU-rich element ; cSNP ; single nucleotide polymorphisms in coding regions ; HRE ; hypoxia responsive element ; IRES ; internal ribosomal entry site ; OSCC ; oral squamous cell carcinoma ; rSNPs ; single nucleotide polymorphisms in regulatory regions ; SNP ; single nucleotide polymorphisms ; sSNP ; single nucleotide polymorphisms in splicing regions ; TFB ; transcription factor binding ; TFBS ; transcription factor bindin

刊名：Cytokine

出版年：2015