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在“Elsevier电子期刊”中，命中：26条，耗时：0.0709659 秒

在所有数据库中总计命中：1,683条

1.Clementine juice has the potential for drug interactions - In vitro comparison with grapefruit and mandarin juice

作者：Dirk Theile^a ; ¹ ; Nicolas Hohmann^a ; ¹ ; Dominik Kiemel^a ; Giuseppe Gattuso^b ; Davide Barreca^b ; Gerd Mikus^a ; Walter Emil Haefeli^a ; Vedat Schwenger^c ; ^d ; ¹ ; Johanna Weiss^a ; ¹ ; ^{johanna.weiss@med.uni-heidelberg.de}

关键词：Clementine ; CYPs ; Drug transporters ; Grapefruit ; Mandarin ; HPLC-DAD-ESI-MS-MS

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.A scavenger peptide prevents methylglyoxal induced pain in mice

作者：Sebastian Brings^a ; ^b ; ^{sebastian.brings@med.uni-heidelberg.de} ; Thomas Fleming^a ; ^c ; Svenja De Buhr^b ; Barbro Beijer^b ; Thomas Lindner^b ; Artjom Wischnjow^b ; Zoltan Kender^e ; Verena Peters^f ; Stefan Kopf^a ; Uwe Haberkorn^b ; Walter Mier^b ; Peter P. Nawroth^a ; ^c ; ^d

关键词：Methylglyoxal ; Scavenger ; Peptide ; Pain ; Diabetic complications

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

3.Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry after chlorzoxazone microdosing

作者：Lukas Witt^a ; ¹ ; Yosuke Suzuki^a ; ^b ; ¹ ; Nicolas Hohmann^a ; Gerd Mikus^a ; Walter E. Haefeli^a ; Jü ; rgen Burhenne^a ; ^{juergen.burhenne@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Chlorzoxazone ; 6-hydroxychlorzoxazone ; CYP2E1 ; Microdosing ; Ultra high performance liquid chromatography ; Tandem mass spectrometry

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

4.First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B

作者：Antje Blank¹ ; ² ; ^{antje.blank@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Christoph Markert¹ ; Nicolas Hohmann¹ ; Alexandra Carls¹ ; Gerd Mikus¹ ; Thorsten Lehr³ ; Alexander Alexandrov⁴ ; Mathias Haag⁵ ; ⁶ ; ⁷ ; Matthias Schwab⁵ ; ⁶ ; ⁷ ; ⁸ ; Stephan Urban² ; ⁹ ; Walter E. Haefeli¹ ; ²

关键词：NTCP ; sodium taurocholate co-transporting polypeptide ; HBV ; hepatitis B virus ; CHB ; chronic hepatitis B ; HDV ; hepatitis D virus ; DSMB ; data and safety monitoring board ; MABEL ; minimal anticipated biologic effect level ; AE ; adverse event ; ECG ; electrocardiogram ; CTC-AE ; common terminology criteria for adverse events ; LOQ ; limit of quantification ; NCA ; non-compartmental analysis ; NLME ; nonlinear mixed effects ; OFV ; objective function value ; BMI ; body mass index ; VPC ; visual prediction check ; AUC

刊名：Journal of Hepatology

出版年：2016

5.Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study

作者：Pavel Bogomolov¹ ; ² ; Alexander Alexandrov³ ; Natalia Voronkova¹ ; ² ; Maria Macievich¹ ; ² ; Ksenia Kokina¹ ; ² ; Maria Petrachenkova¹ ; ² ; Thorsten Lehr⁴ ; Florian A. Lempp⁵ ; ⁶ ; Heiner Wedemeyer⁷ ; Mathias Haag⁸ ; ⁹ ; ¹⁰ ; Matthias Schwab⁸ ; ⁹ ; ¹⁰ ; ¹¹ ; ¹² ; Walter E. Haefeli⁵ ; ¹³ ; Antje Blank⁵ ; ¹³ ; ^&dagger ; ; ^{antje.blank@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author} ; Stephan Urban⁵ ; ⁶ ; ^&dagger ;

关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; BSA ; bovine serum albumin ; blq ; below limit of quantification ; cccDNA ; covalently closed circular deoxyribonucleic acid ; CHB ; chronic hepatitis B ; CHD ; chronic hepatitis D ; d ; hepatocyte death rate ; DNA ; deoxyribonucleic acid ; HBeAg ; HBe antigen ; HBsAg ; HBs antigen ; HBV ; hepatitis B virus ; HDV ; hepatitis D virus ; IFN ; interferon ; lod ; limit of detection ; loq ; limit of quantification ; NOEL ; no observed effect level ; NLME ; non-linear

刊名：Journal of Hepatology

出版年：2016

6.What, if all alerts were specific - Estimating the potential impact on drug interaction alert burden

作者：Hanna M. Seidling^a ; ^b ; Ulrike Klein^c ; Matthias Schaier^d ; David Czock^a ; Dirk Theile^a ; Markus G. Pruszydlo^a ; Jens Kaltschmidt^a ; Gerd Mikus^a ; Walter E. Haefeli^a ; ^b ; ^{walter.emil.haefeli@med.uni-heidelberg.de" class="auth_mail}

关键词：Clinical decision support systems ; Drug&ndash ; drug interactions ; Alert fatigue ; Alert specificity

刊名：International Journal of Medical Informatics

出版年：April, 2014

7.Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Reference data for the trunk and application in patients with chronic postherpetic neuralgia

作者：Doreen B. Pfau^a ; ¹ ; ^{doreen.pfau@medma.uni-heidelberg.de" class="auth_mail} ; Elena K. Krumova^b ; ¹ ; Rolf-Detlef Treede^a ; ² ; Ralf Baron^c ; ² ; Thomas Toelle^d ; ² ; Frank Birklein^e ; Wolfgang Eich^f ; Christian Geber^e ; Andreas Gerhardt^f ; Thomas Weiss^g ; Walter Magerl^a ; Christoph Maier^h ; ²

关键词：QST ; Thermal ; Mechanical ; Detection ; Pain ; Male ; Female ; Gender ; Reference data ; Test-retest reliability

刊名：Pain

出版年：May, 2014

8.Cyclosporin A inhibits hepatitis B and hepatitis D virus entry by cyclophilin-independent interference with the NTCP receptor

作者：Shirin Nkongolo¹ ; ^&dagger ; ; Yi Ni¹ ; ^&dagger ; ; Florian A. Lempp¹ ; Christina Kaufman¹ ; ² ; Thomas Lindner² ; Katharina Esser-Nobis¹ ; Volker Lohmann¹ ; Walter Mier² ; Stefan Mehrle¹ ; Stephan Urban¹ ; ^{Stephan.Urban@med.uni-heidelberg.de" class="auth_mail}

关键词：HBV ; hepatitis B virus ; HBsAg ; hepatitis B surface antigen ; HDV ; hepatitis delta virus ; NTCP ; sodium taurocholate co-transporting polypeptide ; TC ; taurocholate ; CsA ; cyclosporin A ; HCV ; hepatitis C virus ; hNTCP ; human sodium taurocholate co-transporting polypeptide ; mNTCP ; mouse sodium taurocholate co-transporting polypeptide ; GFP ; green fluorescent protein ; PHH ; primary human hepatocytes ; DMSO ; dimethyl sulfoxide ; MyrB ; Myrcludex B ; HBeAg ; hepatitis B virus early antigen ; IF ; immunofluorescence

刊名：Journal of Hepatology

出版年：April, 2014

9.Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

作者：Jannick Clemens^a ; Magdalena Longo^a ; Anja Seckinger^b ; Dirk Hose^b ; Walter Emil Haefeli^a ; Johanna Weiss^a ; ¹ ; Jü ; rgen Burhenne^a ; ¹ ; ^{juergen.burhenne@med.uni-heidelberg.de" class="auth_mail}

关键词：Bortezomib ; Drug stability ; Culture medium ; Multiple myeloma ; Tandem mass spectrometry

刊名：Journal of Chromatography A

出版年：6 June 2014

10.Interaction profile of macitentan, a new non-selective endothelin-1 receptor antagonist, in vitro

作者：Johanna Weiss ; ^{johanna.weiss@med.uni-heidelberg.de} ; Dirk Theile ; Maximilian Alexander Rü ; ppell ; Tobias Speck ; Adriana Spalwisz ; Walter Emil Haefeli

关键词：Macitentan ; Pulmonary arterial hypertension ; Drug transporter ; Drug metabolising enzymes ; Induction

刊名：European Journal of Pharmacology

出版年：2013

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