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在“Elsevier电子期刊”中，命中：3,680条，耗时：0.0619383 秒

在所有数据库中总计命中：22,336条

1.New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT₇ and 5-HT_1A receptor ligands: Synthesis, structure-activity relationships, and molecular modeling studies

作者：Sebastiano Intagliata^a ; ¹ ; ^{s.intagliata@studium.unict.it} ; Maria N. Modica^a ; ¹ ; Valeria Pittalà ; ^a ; Loredana Salerno^a ; Maria A. Siracusa^a ; Alfredo Cagnotto^b ; Mario Salmona^b ; Rafał Kurczab^c ; Giuseppe Romeo^a

关键词：5-HT7 receptor ligands ; 5-HT1A receptor ligands ; Long-chain arylpiperazines ; Molecular modeling

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT_1A receptor over α₁-adrenoceptor and D₂-like receptor subtypes

作者：Fabio Del Bello^a ; ¹ ; Alessandro Bonifazi^a ; ^b ; ¹ ; Mario Giannella^a ; Gianfabio Giorgioni^a ; Alessandro Piergentili^a ; Riccardo Petrelli^a ; Carlo Cifani^a ; Maria Vittoria Micioni Di Bonaventura^a ; Thomas M. Keck^b ; ^c ; ^d ; Angelica Mazzolari^e ; Giulio Vistoli^e ; Antonio Cilia^f ; Elena Poggesi^f ; Rosanna Matucci^g ; Wilma Quaglia^a ; ^{wilma.quaglia@unicam.it}

关键词：5-HT1A receptor ; α1-Adrenoceptor subtypes ; D2-like receptor subtypes ; Selective 5-HT1A receptor agonists ; Docking studies ; Anxiolytic effect

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine 1A and its receptors in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells

作者：Giorgos Bamias^a ; ^{gbamias@gmail.com} ; Eirini Filidou^b ; Dimitris Goukos^c ; Vasilis Valatas^d ; Konstantinos Arvanitidis^b ; Maria Panagopoulou^b ; Georgios Kouklakis^e ; George L. Daikos^c ; Spiros D. Ladas^a ; George Kolios^b

关键词：TL1A ; TNF-like cytokine 1A ; DR3 ; death-domain receptor 3 ; DcR3 ; decoy receptor 3 ; CD ; Crohn's disease ; SEMFs ; subepithelial myofibroblasts

刊名：Translational Research

出版年：2017

4.Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT_1A receptor agonists

作者：Silvia Franchini^a ; Leda Ivanova Manasieva^a ; Claudia Sorbi^a ; Umberto M. Battisti^a ; Paola Fossa^b ; Elena Cichero^b ; Nunzio Denora^c ; Rosa Maria Iacobazzi^c ; ^d ; Antonio Cilia^e ; Lorenza Pirona^e ; Simone Ronsisvalle^f ; Giuseppina Aricò ; ^f ; Livio Brasili^a ; ^{livio.brasili@unimore.it}

关键词：5-HT1A receptor ; Agonist ; Neuroprotection ; BBB penetration ; Analgesic activity

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Serotonin Signaling through Prefrontal Cortex 5-HT_1A Receptors during Adolescence Can Determine Baseline Mood-Related Behaviors

作者：Alvaro L. Garcia-Garcia¹ ; Qingyuan Meng¹ ; Sarah Canetta² ; Alain M. Gardier³ ; Bruno P. Guiard³ ; Christoph Kellendonk² ; ⁴ ; ⁵ ; Alex Dranovsky¹ ; ^{ad722@cumc.columbia.edu} ; E. David Leonardo¹ ; ⁶ ; ^{el367@cumc.columbia.edu}

关键词：serotonin ; 5-HT1A ; depression ; anxiety ; development ; adolescence ; mPFC ; DRN

刊名：Cell Reports

出版年：2017

6.Design and synthesis of novel N-sulfonyl-2-indoles that behave as 5-HT₆ receptor ligands with significant selectivity for D₃ over D₂ receptors

作者：Oscar M. Saavedra^a ; Delphine Karila^a ; Dominique Brossard^a ; Anne Rojas^b ; Delphine Dupuis^c ; Arnaud Gohier^d ; Clotilde Mannoury la Cour^c ; Mark J. Millan^c ; ; Jean-Claude Ortuno^b ; ; Stephen Hanessian^a ;

关键词：Benzocyclobutane ; Indole ; CNS receptors ; Schizophrenia ; Antipsychotic

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

7.Involvement of presynaptic 5-HT_1A receptors in the low propensity of brexpiprazole to induce extrapyramidal side effects in rats

作者：Cedric Mombereau^a ; ^{CMOM@lundbeck.com} ; Jø ; rn Arnt^b ; Arne Mø ; rk^a

关键词：ANOVA ; Analysis of variance ; DA ; Dopamine ; EPS ; Extrapyramidal side effects ; l-DOPA ; l-3 ; 4-dihydroxyphenylalanine ; mPFC ; Medial prefrontal cortex ; 5-HT ; Serotonin

刊名：Pharmacology Biochemistry and Behavior

出版年：2017

8.5-HT1A receptor (HTR1A) 5′ region haplotypes significantly affect protein expression in vitro

作者：Xue Wu ; Jun Yao ; Mei Ding ; Zhang-sen Shi ; Feng-ling Xu ; Jing-jing Zhang ; Bao-jie Wang ; ^{wangbj77@163.com}

关键词：HTR1A ; Polymorphism ; Promoter ; Transcription ; Schizophrenia

刊名：Neuroscience Letters

出版年：2017

9.The 5-HT_1A/1B-receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and “waiting” impulsivity, but increases “stopping” impulsivity

作者：S. Mechiel Korte^a ; ^d ; ^{s.m.korte@uu.nl} ; Jolanda Prins^a ; Filip S. Van den Bergh^a ; Ronald S. Oosting^a ; Rudy Dupree^a ; Gerdien A.H. Korte-Bouws^a ; Koen G.C. Westphal^a ; Berend Olivier^b ; Damiaan A. Denys^c ; Alexis Garland^d ; Onur Gü ; ntü ; rkü ; n^d

关键词：Eltoprazine (PubChem CID ; 65853)

刊名：European Journal of Pharmacology

出版年：2017

10.Serotonin and urocortin 1 in the dorsal raphe and Edinger-Westphal nuclei after early life stress in serotonin transporter knockout rats

作者：Rick H.A. van der Doelen^a ; ^b ; Berit Robroch^b ; Ilse A. Arnoldussen^a ; Maya Schulpen^a ; Judith R. Homberg^b ; ^&dagger ; ; Tamá ; s Kozicz^a ; ^c ; ^&dagger ; ; ^{Tamas.Kozicz@radboudumc.nl}

关键词：5-HT ; 5-hydroxytryptamine ; serotonin ; 5-HT1A ; 5-HT receptor 1A ; 5-HTT ; 5-HT transporter ; 5-HTTLPR ; 5-HT transporter-linked polymorphic region ; CpG ; cytosine-phosphate-guanine ; CRE ; cyclic-AMP response element ; CRF ; corticotropin-releasing factor ; CRF1R ; corticotropin-releasing factor receptor 1 ; CRF2R ; corticotropin-releasing factor receptor 2 ; DR ; dorsal raphe ; DRD ; DR dorsal part ; DRLW ; DR lateral wings ; DRV ; DR ventral part ; ELS ; early life stress ; EWcp ; Edinger&ndash ; Westphal centrally proje

刊名：Neuroscience

出版年：2017

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