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在“Elsevier电子期刊”中，命中：25条，耗时：小于0.01 秒

在所有数据库中总计命中：45条

1.New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model

关键词：Seven transmembrane-spanning receptor (7TMR) ; Two-site model ; Chemokine stoichiometry ; 7TMR activation ; Biased agonism

刊名：Biochemical Pharmacology

出版年：2016

2.Recent updates on GPCR biased agonism

作者：André ; S. Pupo^a ; ^{aspupo@ibb.unesp.br" class="auth_mail" title="E-mail the corresponding author} ; Diego A. Duarte^b ; Vanessa Lima^a ; ^b ; Larissa B. Teixeira^b ; Lucas T. Parreiras-e-Silva^b ; Claudio M. Costa-Neto^b ; ^{claudio@fmrp.usp.br" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCR ; 7TMR ; Functional selectivity

刊名：Pharmacological Research

出版年：2016

3.Synoptic pharmacology: Detecting and assessing the pharmacological significance of ligands for orphan receptors

作者：Terry P. Kenakin ; ^{kenakin@email.unc.edu}

关键词：Receptors ; GPCRs ; Orphan receptors ; Screening ; Constitutive ; activity

刊名：Pharmacological Research

出版年：2016

4.Sulfur-containing amino acids in 7TMRs: molecular gears for pharmacology and function

作者：Arnau Cordomí ; ¹ ; José ; C. Gó ; mez-Tamayo¹ ; Vé ; ronique Gigoux² ; Daniel Fourmy² ; ^{Daniel.Fourmy@inserm.fr}

关键词：GPCR ; crystal structure ; site-directed mutagenesis ; molecular modeling

刊名：Trends in Pharmacological Sciences

出版年：2013

5.Development of allosteric modulators of GPCRs for treatment of CNS disorders

作者：Hilary Highfield Nickols ; P. Jeffrey Conn

关键词：5MPEP ; 5-methyl-6-(phenylethynyl)-pyridine ; 6-OHDA ; 6-hydroxydopamine ; 7TMR ; seven transmembrane receptor ; 77-LH-28-1 ; 1-[3-(4-butyl-1-piperidinyl)propyl]-3 ; 4-dihydro-2(1H)-quinolinone ; AC-42 ; 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine ; AChE ; acetylcholinesterase ; ACPT-1 ; (1S ; 3R ; 4S)-1-aminocyclo-pentane-13 ; 4-tricarboxylic acid ; AD ; Alzheimer's disease ; ADX71743 ; (+)-6-(2 ; 4-dimethylphenyl)-2-ethyl-6 ; 7-dihydrobenzo[d]oxazol-4(5H)-one ; AFQ056 ; (3aS ; 5S ; 7aR)-methyl 5-hydroxy-5-(m-toly

刊名：Neurobiology of Disease

出版年：January, 2014

6.Functional selectivity induced by mGlu₄ receptor positive allosteric modulation and concomitant activation of G_q coupled receptors

作者：Shen Yin ; Rocio Zamorano ; P. Jeffrey Conn ; Colleen M. Niswender ; ^{Colleen.niswender@vanderbilt.edu}

关键词：Glutamate ; Histamine ; Receptor ; Allosteric modulator ; Functional selectivity

刊名：Neuropharmacology

出版年：2013

7.The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

作者：Arturo D. Mancini ; Vincent Poitout

关键词：GPR40/FFA1 ; type 2 diabetes ; pancreatic ¦Â cell ; insulin secretion ; biased agonism

刊名：Trends in Endocrinology and Metabolism

出版年：2013

8.Expression and function of ¦Â-arrestin 2 stimulated by IL-1¦Â in human fibroblast-like synoviocytes and the effect of paeoniflorin

作者：Hua-Xun Wu ^{wuhuaxun@yahoo.cn} ; Jing-Yu Chen ^{cjy.anyi@gmail.com} ; Qing-Tong Wang ^{hfwqt727@163.com} ; Wu-Yi Sun ; Li-Hua Liu ^{liulihuawomen@hotmail.com} ; Ling-Ling Zhang ^{llzhang@ahmu.edu.cn} ; Wei Wei ; ^{wwei@ahmu.edu.cn}

关键词：RA ; rheumatoid arthritis ; AA ; adjuvant arthritis ; CIA ; collagen-induced arthritis ; FLS ; fibroblast-like synoviocytes ; GPCRs ; G-protein-coupled receptors ; Pae ; paeoniflorin ; PBMC ; peripheral blood mononuclear cells ; MLN ; mesenteric lymph nodes ; 7TMRs ; 7 tr

刊名：International Immunopharmacology

出版年：2012

9.Characterizing and predicting the functional and conformational diversity of seven-transmembrane proteins

作者：Ravinder Abrol^a ; ^{abrol@wag.caltech.edu} ; Soo-Kyung Kim^a ; Jenelle K. Bray^b ; Adam R. Griffith^a ; William A. Goddard III^a

关键词：G protein-coupled receptors ; GPCRs ; Conformational ensemble ; Functional selectivity ; Protein structure prediction ; Transmembrane helix topology

刊名：Methods

出版年：2011

10.AT₁ receptor Gαq protein-independent signalling transcriptionally activates only a few genes directly, but robustly potentiates gene regulation from the β2-adrenergic receptor

作者：Gitte L. Christensen ; Steen Knudsen ; Mikael Schneider ; Mark Aplin ; Steen Gammeltoft ; Sø ; ren P. Sheikh ; Jakob L. Hansen

关键词：Angiotensin II type 1 receptor ; Gene expression ; Microarray ; Biased agonist ; 7TMR ; transcription factor

刊名：Molecular and Cellular Endocrinology

出版年：2011

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