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在“Elsevier电子期刊”中，命中：67条，耗时：小于0.01 秒

1.Metabolic preconditioning protects BSEP/ABCB11^−/− mice against cholestatic liver injury

作者：Claudia D. Fuchs¹ ; Gustav Paumgartner¹ ; Annika Wahlströ ; m² ; Philipp Schwabl³ ; Thomas Reiberger³ ; Nadja Leditznig¹ ; Tatjana Stojakovic⁴ ; Nataliya Rohr-Udilova³ ; ⁵ ; Peter Chiba⁶ ; Hanns-Ulrich Marschall² ; Michael Trauner¹ ; ^{michael.trauner@meduniwien.ac.at}

关键词：Bile salt export pump ; Polyhydroxylated bile acids ; Intrahepatic cholestasis

刊名：Journal of Hepatology

出版年：2017

2.Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice

作者：Mariana Acuñ ; a¹ ; ⁵ ; ^&dagger ; ; Lila Gonzá ; lez-Hó ; dar¹ ; ^&dagger ; ; Ludwig Amigo¹ ; Juan Castro¹ ; M. Gabriela Morales¹ ; Gonzalo I. Cancino² ; Albert K. Groen³ ; Juan Young⁴ ; Juan Francisco Miquel¹ ; ⁵ ; Silvana Zanlungo¹ ; ⁵ ; ^{silvana@med.puc.cl" class="auth_mail" title="E-mail the corresponding author}

关键词：NPC2 ; Niemann-Pick C2 ; NPC1 ; Niemann-Pick C1 ; NPC2(h/h) ; Niemann-Pick C2-deficient hypomorph mice ; ABCG5/G8 ; adenosine triphosphate&ndash ; binding cassettes G5 and G8 ; ConA ; Concanavalin A ; Npc2.Tg ; Niemann-Pick C2 transgenic mice ; PCR ; polymerase chain reaction ; qPCR ; quantitative polymerase chain reaction ; HEK ; human embryonic kidney ; BSA ; bovine serum albumin ; ALT ; alanine transaminase ; Abcb11 ; ATP-binding cassette ; sub-family B member 11 ; Abcb4 ; ATP-binding cassette ; sub-family B member 4 ; CS

刊名：Journal of Hepatology

出版年：2016

3.Nanoencapsulated curcumin and praziquantel treatment reduces periductal fibrosis and attenuates bile canalicular abnormalities in Opisthorchis viverrini-infected hamsters

作者：Lakhanawan Charoensuk ; MSc^a ; ^d ; Porntip Pinlaor ; PhD^d ; ^e ; Supason Wanichwecharungruang ; PhD^g ; Kitti Intuyod ; BSc^d ; ^f ; Kulthida Vaeteewoottacharn ; MD. PhD^b ; ^d ; Apisit Chaidee ; BSc^a ; ^d ; Puangrat Yongvanit ; PhD^b ; ^d ; Chawalit Pairojkul ; MD^c ; ^d ; Natthakitta Suwannateep ; PhD^h ; Somchai Pinlaor ; PhD^a ; ^d ; ^{psomec@kku.ac.th" class="auth_mail" title="E-mail the corresponding author}

关键词：OV ; Opisthorchis viverrini ; CCA ; cholangiocarcinoma ; NEC ; nanoencapsulated curcumin ; PZQ ; praziquantel ; PDF ; periductal fibrosis ; BC ; bile canaliculi ; Cur ; curcumin ; ALT ; alanine transaminase ; MMP ; matrix metalloproteinases ; TIMP ; tissue inhibitors of MMPs ; CTGF ; connective tissue growth factor ; α-SMA ; alpha-smooth muscle actin ; TGF-β ; transforming growth factor beta ; TNF-α ; tumor necrosis factor alpha ; abcb11 ; ATP-binding cassette sub-family B member 11 ; abcc2 ; ATP-binding cassette sub-family C

刊名：Nanomedicine: Nanotechnology, Biology and Medicine

出版年：2016

4.Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse

作者：Jie Zhang^a ; ¹ ; ^{jie.zhang@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author} ; Kan He^b ; ¹ ; ^{khe@biotranex.com" class="auth_mail" title="E-mail the corresponding author} ; Lining Cai^b ; Yu-Chuan Chen^a ; Yifan Yang^b ; Qin Shi^b ; Thomas F. Woolf^b ; Weigong Ge^a ; Lei Guo^c ; Jü ; rgen Borlak^d ; ¹ ; Weida Tong^a

关键词：Bile salt export pump ; BSEP ; ABCB11 ; Drug-induced liver injury ; DILI ; Bile salts ; Hepatocytes ; Species difference

刊名：Chemico-Biological Interactions

出版年：2016

5.Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice

作者：Rick van der Geest^a ; ^{r.van.der.geest@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Amber B. Ouweneel^a ; ^{a.b.ouweneel@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Ronald J. van der Sluis^a ; ^{r.vandersluis@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Albert K. Groen^b ; ^{a.k.groen@umcg.nl" class="auth_mail" title="E-mail the corresponding author} ; Miranda Van Eck^a ; ^{m.eck@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author} ; Menno Hoekstra^a ; ^{hoekstra@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：ABCB4 ; ATP-binding cassette transporter B4 ; ADX ; adrenalectomy ; ALT/GPT ; alanine transaminase/glutamic pyruvic transaminase ; ANIT ; alpha-naphthylisothiocyanate ; APOA4 ; apolipoprotein A4 ; BSEP/ABCB11 ; bile salt efflux pump ; CYP7A1 ; cholesterol 7alpha-hydroxylase ; FXR/BAR ; farnesoid X receptor/bile acid receptor ; HDL ; high-density lipoprotein ; HMGCR ; HMG-CoA reductase ; LDL ; low-density lipoprotein ; LDLR ; low-density lipoprotein receptor ; NTCP1/SLC10A1 ; sodium/bile acid cotransporter member 1 ; PEPC

刊名：Toxicology and Applied Pharmacology

出版年：2016

6.746 Absence of BSEP/ABCB11 Protects From Cholestatic Liver Injury in Mice

作者：Claudia D. Fuchs ; Gustav Paumgartner ; Annika Wahlström ; Tatjana Stojakovic ; Thierry Claudel ; Hanns-Ulrich Marschall ; Michael H. Trauner

刊名：Gastroenterology

出版年：2016

7.Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid

作者：Noortje Ijssennagger¹ ; Aafke W.F. Janssen² ; Alexandra Milona¹ ; José ; M. Ramos Pittol¹ ; Danielle A.A. Hollman¹ ; Michal Mokry³ ; Bark Betzel⁴ ; Frits J. Berends⁴ ; Ignace M. Janssen⁴ ; Saskia W.C. van Mil¹ ; ^&dagger ; ; ^{S.W.C.vanmil@umcutrecht.nl" class="auth_mail" title="E-mail the corresponding author} ; Sander Kersten² ; ^&dagger ;

关键词：FXR ; farnesoid X Receptor ; OCA ; obeticholic acid ; NASH ; non-alcoholic steatohepatitis ; hPCLS ; human precision cut liver slices ; LDL ; low density lipoprotein ; HDL ; high density lipoprotein ; NAFLD ; non-alcoholic fatty liver disease ; DMSO ; dimethyl sulfoxide ; WT ; wild-type ; RMA ; robust multi-array analysis ; IBMT ; Intensity-Based Moderated T-statistic ; bp ; base pair ; TSS ; transcription start site ; IR1 ; inverted NR-hexamer sequence

刊名：Journal of Hepatology

出版年：2016

8.Hypothyroidism Associated with ATP8B1 Deficiency

作者：Liting Li ; PhD¹ ; Maesha Deheragoda ; MD ; PhD² ; Yi Lu ; MD¹ ; Jingyu Gong ; MD³ ; Jianshe Wang ; MD ; PhD¹ ; ³ ; ^{jshwang@shmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：ABCB11 ; ATP-binding cassette ; subfamily B (MDR/TAP) ; member 11 ; ATP8B1 ; ATPase ; aminophospholipid transporter ; class I ; type 8B ; member 1 ; BRIC ; Benign recurrent intrahepatic cholestasis ; BSEP ; Bile salt export pump ; GGT ; γ-glutamyltransferase ; L-T4 ; Levo-thyroxine ; MRP2 ; Multidrug resistance-associated protein 2 ; OMIM ; Online Mendelian Inheritance in Man ; PCR ; Polymerase chain reaction ; PFIC ; Progressive familial intrahepatic cholestasis ; TJP2 ; Tight junction protein 2 ; TSH ; Thyroid-stimulating

刊名：The Journal of Pediatrics

出版年：2015

9.Transcriptome analysis of grass carp (Ctenopharyngodon idella) fed with animal and plant diets

作者：Ling Li^a ; Xu-Fang Liang^a ; ^{xfliang@mail.hzau.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Shan He^a ; Jian Sun^a ; Zheng-Yong Wen^a ; Yu-Hui He^a ; Wen-Jing Cai^a ; Ya-Ping Wang^b ; Ya-Xiong Tao^c

关键词：ABCA1 ; ATP-binding cassette ; sub-family A ; member 1 ; ABCB11/BSEP ; ATP-binding cassette ; sub-family B (MDR/TAP) ; member 11 ; ABCC2/MRP2 ; ATP-binding cassette ; sub-family C (CFTR/MRP) ; member 2 ; Akt ; serine/threonine-protein kinase ; ANOVA ; one-way analysis of variance ; ApoA-IV ; apolipoprotein A-IV ; ApoB ; apolipoprotein B ; Arntl2 ; aryl hydrocarbon receptor nuclear translocator-like protein 2 ; Bhlhb/Dec ; class B basic helix-loop-helix protein ; BSSL/CEL ; bile salt-stimulated lipase ; CELA ; chymotrypsin

刊名：Gene

出版年：2015

10.Taking the next step forward - Diagnosing inherited infantile cholestatic disorders with next generation sequencing

作者：S.M. Herbst^a ; ¹ ; ^{saskia.herbst@ukr.de" class="auth_mail" title="E-mail the corresponding author} ; S. Schirmer^a ; ¹ ; C. Posovszky^c ; F. Jochum^d ; T. Rö ; dl^a ; J.A. Schroeder^f ; T.F. Barth^e ; U. Hehr^a ; M. Melter^b ; J. Vermehren^b

关键词：Next generation sequencing ; Infantile cholestasis ; PFIC ; Niemann&ndash ; Pick-syndrome ; PKHD1 ; Hepatic fibrosis ; Massive parallel sequencing

刊名：Molecular and Cellular Probes

出版年：2015

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