搜索页_+Anti-Alzheimer

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在“Elsevier电子期刊”中，命中：1,113条，耗时：0.0489796 秒

在所有数据库中总计命中：6,804条

1.A metabolic profiling approach to an Italian sage leaf extract (SoA541) defines its antioxidant and anti-acetylcholinesterase properties

作者：Severina Pacifico^a ; ^{severina.pacifico@unina2.it} ; Simona Piccolella^a ; Annamaria Lettieri^a ; Paola Nocera^a ; Flavia Bollino^b ; Michelina Catauro^b

关键词：LC-MS/MS ; liquid chromatography mass/mass spectrometry ; CNS ; central nervous system ; AD ; Alzheimer&rsquo ; s Disease ; AChE ; acetylcholinesterase ; AChEI ; acetylcholinesterase inhibitors ; UAM ; ultrasound assisted maceration ; LLE ; liquid liquid extraction ; Q ; quercetin ; RA ; rosmarinic acid ; CA ; carnosic acid ; MTT ; 3-(4 ; 5-dimethyl-2-thiazolyl)-2 ; 5-diphenyl-2H-tetrazolium bromide ; TBARS ; ThioBarbituric Acid Reactive Species ; DCFH-DA ; 2&prime ; 7&prime ; -dichlorofluorescein diacetate ; CAA ; cellular antiox

刊名：Journal of Functional Foods

出版年：2017

2.The effects of fluorine substitution on the chemical properties and inhibitory capacity of Donepezil anti-Alzheimer drug; density functional theory and molecular docking calculations

作者：Azita Khosravan^a ; ^{a.khosravan@kgut.ac.ir} ; Safora Marani^b ; Mohammad Sadegh Sadeghi Googheri^b ; ^c ; ^{sadeghi.mohammadsadegh@gmail.com}

关键词：Alzheimer disease ; Donepezil ; Fluorination ; Molecular docking ; Density functional theory ; AIM ; NBO

刊名：Journal of Molecular Graphics and Modelling

出版年：2017

3.Alzheimer’s disease: Development of a sensitive label-free electrochemical immunosensor for detection of amyloid beta peptide

作者：Pedro Carneiro^a ; ^bAuthor Vitae ; Joana Loureiro^aAuthor Vitae ; Cristina Delerue-Matos^bAuthor Vitae ; Simone Morais^b ; ^{sbm@isep.ipp.pt" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; Maria do Carmo Pereira^aAuthor Vitae

关键词：Alzheimer&rsquo ; s disease ; β-Amyloid peptide ; Electrochemical biosensor ; Self-assembled monolayer ; Gold nanoparticles ; Monoclonal antibody

刊名：Sensors & Actuators: B. Chemical

出版年：2017

4.Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer’s disease agents

作者：William Horton^a ; Abha Sood^a ; Swarada Peerannawar^a ; Nandor Kugyela^a ; Aditya Kulkarni^a ; Rekha Tulsan^a ; Chris D. Tran^a ; Jessica Soule^a ; Harry LeVine III^b ; Bé ; la Tö ; rö ; k^a ; Marianna Tö ; rö ; k^a ; ^{marianna.torok@umb.edu}

关键词：Alzheimer&rsquo ; s disease ; Amyloid beta ; Cholinesterase inhibition ; Antioxidant ; β-Carbolines

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

5.In vitro effects of the anti-Alzheimer drug memantine on the human erythrocyte membrane and molecular models

作者：Pablo Zambrano^a ; Mario Suwalsky^a ; ^{msuwalsk@udec.cl} ; Fernando Villena^b ; Malgorzata Jemiola-Rzeminska^c ; ^d ; Kazimierz Strzalka^c ; ^d

关键词：Memantine ; Human erythrocyte ; Cell membrane ; Phospholipid bilayer

刊名：Biochemical and Biophysical Research Communications

出版年：2017

6.N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer’s agents

作者：Urban Ko&scaron ; ak^a ; Damijan Knez^a ; Nicolas Coquelle^b ; Boris Brus^a ; Anja Pi&scaron ; lar^a ; Florian Nachon^c ; Xavier Brazzolotto^c ; Janko Kos^a ; Jacques-Philippe Colletier^b ; Stanislav Gobec^a ; ^{stanislav.gobec@ffa.uni-lj.si}

关键词：Multitarget-directed ligands ; Butyrylcholinesterase inhibitors ; MAO-B inhibitors ; Alzheimer&rsquo ; s disease

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

7.Synergistic effect of tanshinone IIA and mesenchymal stem cells on preventing learning and memory deficits via anti-apoptosis, attenuating tau phosphorylation and enhancing the activity of central cholinergic system in vascular dementia

作者：Deyan Kong^a ; ¹ ; ^{kongdeyangxnn@163.com} ; Qian Liu^b ; ¹ ; ^{conneym@163.com} ; Guangxu Xu^c ; ^{xuguangxu1@126.com} ; Zhenhua Huang^d ; ^{huangzhenhuakdy@163.com} ; Ning Luo^a ; ^{ln760320@163.com} ; Yuanheng Huang^e ; ^{huangyuanheng@163.com} ; Keshu Cai^c ; ^{caikeshu@sina.com}

关键词：VaD ; vascular dementia ; MSCs ; mesenchymal stem cells ; 4-VO ; four-vessel occlusion ; TSA ; tanshinone II A ; AD ; Alzheimer&rsquo ; s disease ; MWM ; morris water maze ; GSK 3β ; glycogen synthase kinase 3β ; ACh ; acetylcholine ; ChAT ; choline acetyltransferase ; AChE ; acetylcholinesterase ; PBS ; phosphate-buffered saline

刊名：Neuroscience Letters

出版年：2017

8.Huperzine A: A promising anticonvulsant, disease modifying, and memory enhancing treatment option in Alzheimer’s disease

作者：Ugur Damar^a ; Roman Gersner^a ; Joshua T. Johnstone^b ; Steven Schachter^c ; Alexander Rotenberg^a ; ^{Alexander.Rotenberg@childrens.harvard.edu}

关键词：Huperzine A ; Acetylcholinesterase ; Nicotinic ; Seizure ; Alzheimer&rsquo ; s disease ; Antiepileptic ; ppTMS

刊名：Medical Hypotheses

出版年：2017

9.Genome-wide pathway-based association analysis identifies risk pathways associated with Parkinson’s disease

作者：Mingming Zhang^a ; ^&dagger ; ; Hongbo Mu^b ; ^&dagger ; ; Zhenwei Shang^a ; ^&dagger ; ; Kai Kang^c ; ^&dagger ; ; Hongchao Lv^a ; Lian Duan^a ; Jin Li^a ; Xinren Chen^a ; Yanbo Teng^a ; Yongshuai Jiang^a ; ^{jiangyongshuai@gmail.com} ; Ruijie Zhang^a ; ^{zhangruijie_2015@163.com}

关键词：AD ; Alzheimer&rsquo ; s disease ; CAMs ; cell adhesion molecules ; dbGaP ; Genotypes and Phenotypes ; ECM ; extra cellular matrix ; FAK ; focal adhesion kinase ; FAs ; focal adhesions ; FDR ; false discovery rate ; GWAS ; genome-wide association study ; HLA ; Human Leucocyte Antigen ; HWE ; Hardy&ndash ; Weinberg equilibrium ; KEGG ; Kyoto Encyclopedia of Genes and Genomes ; LD ; Linkage disequilibrium ; NINDS ; National Institute of Neurological Disorders and Stroke ; PD ; Parkinson&rsquo ; s disease ; RA ; rheumatoid arthritis

刊名：Neuroscience

出版年：2017

10.Network pharmacology-based study on the mechanism of action for herbal medicines in Alzheimer treatment

作者：Jiansong Fang^a ; ^b ; Ling Wang^c ; Tian Wu^a ; ^b ; Cong Yang^a ; ^b ; Li Gao^d ; Haobin Cai^a ; ^b ; Junhui Liu^e ; Shuhuan Fang^a ; ^b ; Yunbo Chen^a ; ^b ; Wen Tan^f ; ^{went@scut.edu.cn} ; Qi Wang^a ; ^b ; ^{wqitcm@qq.com}

关键词：AD ; Alzheimer's disease ; NFT ; neurofibrillary tangles ; ChE ; cholinesterase ; NMDA ; N-methyl-D-aspartate ; TCM ; Traditional Chinese Medicine ; MOA ; mechanisms of action ; TCMSP ; traditional Chinese medicine systems pharmacology ; TCMID ; traditional Chinese medicine integrative database ; MW ; molecular weight ; HBAs ; the number of H acceptors ; HBDs ; the number of H donors ; logPo/w ; Log octanol/water partition coefficient ; b_rotN ; the number of rotable bonds ; TPSA ; topological polar surface area ; logS ; Lo

刊名：Journal of Ethnopharmacology

出版年：2017

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