搜索页_+Caspase+inhibitors

常用资源

电子图书

期刊论文

学位会议

在“Elsevier电子期刊”中，命中：1,877条，耗时：0.0189934 秒

在所有数据库中总计命中：14,447条

1.Ser⁴²² phosphorylation blocks human Tau cleavage by caspase-3: Biochemical implications to Alzheimer’s Disease

作者：Priya Sandhu^a ; Mansur Mohammad Naeem^a ; Chunyu Lu^a ; Premkumari Kumarathasan^b ; James Gomes^a ; Ajoy Basak^a ; ^c ; ¹ ; ^{abasa2@uottawa.ca}

关键词：Aa ; amino acid ; ACN ; acetonitrile ; AUFS ; absorbance units full scale ; CHCA ; 1-Cyano 4-Hydroxy Cinnamic Acid ; Da ; Dalton ; DHB ; 2 ; 5-dihydroxy benzoic acid ; DMF ; N ; N&prime ; -dimethyl formamide ; EDT ; ethane dithiol ; h ; human ; HATU ; 1-[Bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxid hexafluorophosphate ; HBTU ; NN ; N&prime ; N&prime ; -Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate ; HOBT ; 1-hydroxy benzotriazole ; kDa ; kilo Dalton ; MALDI-Tof MS ; matrix assisted laser

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

3.Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers

作者：A.V. Subba Rao^a ; ^b ; Konderu Swapna^c ; Siddiq Pasha Shaik^a ; ^b ; V. Lakshma Nayak^a ; T. Srinivasa Reddy^c ; Satish Sunkari^a ; ^b ; Thokhir Basha Shaik^a ; Chandrakant Bagul^c ; Ahmed Kamal^a ; ^b ; ^c ;

关键词：Combretastatin A-4 ; Benzothiazole ; Triazoles and tetrazoles ; Antiproliferative activity ; Tubulin polymerization ; Colchicine competition assay ; Apoptosis

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

4.In vitro evaluation of penta-O-galloyl-β-d-glucose (PGG) on miRNA expression and apoptosis in BCR-ABL⁺ ALL

作者：N.S. Sanddhya^a ; ^{sanddhya_23@yahoo.com} ; R. Stalin^a ; P. Sachdanandam^a ; R. Malathi^b ; P. Shanthi^a ; ^{shanthipalanivelu@gmail.com}

关键词：HDACi ; histone deacetylase inhibitors ; ATCC ; the American Type Culture Condition ; PGG ; penta-O-galloyl-β-d-glucose ; ALL ; Acute Lymphoblastic Leukemia

刊名：Gene Reports

出版年：2017

5.Microcystin-LR induced liver injury in mice and in primary human hepatocytes is caused by oncotic necrosis

作者：Benjamin L. Woolbright^a ; ^{bwoolbright@kumc.edu} ; C. David Williams^a ; Hongmin Ni^a ; Sean C. Kumer^b ; Timothy Schmitt^b ; Bartholomew Kane^b ; Hartmut Jaeschke^a

关键词：Microcystin ; Apoptosis ; Hepatocytes ; Transporters ; Necrosis ; Primary human hepatocytes

刊名：Toxicon

出版年：2017

6.miR-200c enhances sensitivity of drug-resistant non-small cell lung cancer to gefitinib by suppression of PI3K/Akt signaling pathway and inhibites cell migration via targeting ZEB1

作者：Guohua Zhou^a ; Fangli Zhang^a ; Yu Guo^a ; Jianfei Huang^a ; Yaqiong Xie^a ; Shuanglei Yue^a ; Minghui Chen^a ; Hao Jiang^b ; Mengjie Li^c ; ^{522237197@qq.com}

关键词：miR-200c ; Drug-resistance ; NSCLC ; PI3K

刊名：Biomedicine & Pharmacotherapy

出版年：2017

7.Rutin protects endothelial dysfunction by disturbing Nox4 and ROS-sensitive NLRP3 inflammasome

作者：Wei Wang¹ ; Qiu-hong Wu¹ ; Yong Sui ; Yan Wang ; Xin Qiu ; ^{pluxud@sina.com}

关键词：Rutin ; High glucose ; Endothelial dysfunction ; Nox4 ; ROS ; NLRP3 inflammasome

刊名：Biomedicine & Pharmacotherapy

出版年：2017

8.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

9.Down-regulation of Na⁺/H⁺ exchanger 1 by Toll-like receptor stimulation in macrophages

作者：Shiho Takakuwa ; Natsumi Mizuno ; Takayuki Takano ; Sanki Asakawa ; Taiki Sato ; Masahiro Hiratsuka ; Noriyasu Hirasawa ; ^{hirasawa@m.tohoku.ac.jp}

关键词：Na+/H+ exchanger 1 ; Lipopolysaccharide ; Macrophage ; c-Jun N-terminal kinase

刊名：Immunobiology

出版年：2017

10.In vitro antiglioma action of indomethacin is mediated via AMP-activated protein kinase/mTOR complex 1 signalling pathway

作者：Aleksandar Pantovic^a ; ¹ ; Mihajlo Bosnjak^b ; ¹ ; Katarina Arsikin^c ; Milica Kosic^c ; Milos Mandic^c ; Biljana Ristic^c ; Jelena Tosic^d ; Danica Grujicic^e ; Aleksandra Isakovic^d ; Nikola Micic^d ; Vladimir Trajkovic^c ; ^{vtrajkovic@med.bg.ac.rs} ; Ljubica Harhaji-Trajkovic^f ; ^{buajk@yahoo.com}

关键词：Indomethacin ; Glioma ; Apoptosis ; AMPK ; mTOR

刊名：The International Journal of Biochemistry & Cell Biology

出版年：2017

按检索点细分(1877)

题名(128)

关键词(65)

文摘(1724)

按出版年细分(1877)

2027年及以后(47)

2017年(10)

2016年(47)

2015年(16)

2014年(1)

2013年(111)

2012年(102)

2011年(113)

2010年(109)

2009年(133)

2008年(142)

2007年(142)

2006年(125)

2005年(103)

2004年(120)

2003年(122)

2002年(92)

2001年(75)

2000年(96)

2000年及以前(171)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700