搜索页_+Copy+number+alterations

常用资源

电子图书

期刊论文

学位会议

在“Elsevier电子期刊”中，命中：489条，耗时：0.0729667 秒

在所有数据库中总计命中：2,654条

1.Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis

作者：Heidi V.N. Kü ; sters-Vandevelde^a ; ¹ ; ^{h.kusters@cwz.nl} ; Vibeke Kruse^b ; ¹ ; ^{Vibeke.Kruse@uzgent.be} ; Tom Van Maerken^c ; ^{Tom.VanMaerken@ugent.be} ; Tom Boterberg^d ; ^{Tom.Boterberg@uzgent.be} ; Rolph Pfundt^e ; ^{Rolph.Pfundt@radboudumc.nl} ; David Creytens^f ; ^{David.Creytens@uzgent.be} ; Caroline Van den Broecke^f ; ^{cvdbroec@me.com} ; Trudi C. Machielsen^e ; ^{Trudi.Machielsen@radboudumc.nl} ; Christian Koelsche^g ; ^{Christian.Koelsche@med.uni-heidelberg.de} ; Andreas von Deimling^g ; ^{Andreas.vonDeimling@med.uni-heidelberg.de} ; Benno Kü ; sters^h ; ⁱ ; ^{Benno.Kusters@radboudumc.nl} ; Patricia J.T.A. Groenen^h ; ^{Patricia.Groenen@radboudumc.nl} ; Pieter Wesseling^j ; ^k ; ^{p.wesseling@vumc.nl} ; Willeke A.M. Blokx^h ; ^{Willeke.Blokx@radboudumc.nl}

关键词：Meningeal melanocytic tumor ; Meningeal melanoma ; Liver metastasis ; GNAQ ; Copy number variations ; Methylation ; Ipilimumab

刊名：Experimental and Molecular Pathology

出版年：2017

2.Improving estimates of the breakpoints in genome copy number alteration profiles with confidence masks

作者：Jorge Muñ ; oz Minjares ; Yuriy S. Shmaliy ; ^{shmaliy@ugto.mx" class="auth_mail" title="E-mail the corresponding author}

关键词：Copy number alterations ; Jitter distribution ; Breakpoints

刊名：Biomedical Signal Processing and Control

出版年：2017

3.Spectrum of mutations in leiomyosarcomas identified by clinical targeted next-generation sequencing

作者：Paul J Lee^a ; ¹ ; Naomi S. Yoo^a ; ¹ ; Ian S. Hagemann^a ; John D Pfeifer^a ; Catherine E Cottrell^a ; ² ; Haley J Abel^b ; Eric J Duncavage^a ; ^{EDuncavage@path.wustl.edu}

关键词：Leiomyosarcoma ; Molecular diagnostics ; Deep sequencing ; DNA mutational analysis ; Copy number alterations ; DNA sequencing ; Single nucleotide variant

刊名：Experimental and Molecular Pathology

出版年：2017

4.Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays

作者：Svetlana A. Yatsenko ; M.D.^a ; ^b ; ^c ; Priya Mittal ; Ph.D.^c ; ^d ; ^e ; Michelle A. Wood-Trageser ; Ph.D.^f ; Mirka W. Jones ; M.D.^b ; Urvashi Surti ; Ph.D.^a ; ^b ; ^c ; ^d ; Robert P. Edwards ; M.D.^a ; ^d ; Anil K. Sood ; M.D.^g ; Aleksandar Rajkovic ; M.D. ; Ph.D.^a ; ^b ; ^c ; ^d ; ^{rajkovic@upmc.edu}

关键词：Uterine leiomyoma ; uterine leiomyosarcoma ; MED12 mutation negative ; whole exome sequencing ; whole genome copy number analysis

刊名：Fertility and Sterility

出版年：2017

5.Unsupervised Analysis of Array Comparative Genomic Hybridization Data from Early-Onset Colorectal Cancer Reveals Equivalence with Molecular Classification and Phenotypes

作者：Marí ; a Arriba^* ; ² ; Juan L. Garcí ; a^&dagger ; ; ^&Dagger ; ; ² ; Daniel Rueda^§ ; ; Jessica Pé ; rez^&dagger ; ; ^&Dagger ; ; Lorena Brandariz^¶ ; ; Oana A. Nutu^¶ ; ; Laura Alonso^¶ ; ; Yolanda Rodrí ; guez^# ; Miguel Urioste^** ; ^&dagger ; &dagger ; ; Rogelio Gonzá ; lez-Sarmiento^&dagger ; ; ^&Dagger ; ; José ; Perea^* ; ^¶ ; ; ^{josepereag@hotmail.com}

关键词：aCGH ; array comparative genomic hybridization ; CIMP ; CpG island methylator phenotype ; CIN ; chromosomal instability ; CNA ; copy number alteration ; CRC ; colorectal cancer ; DFS ; disease-free survival ; EOCRC ; early-onset colorectal cancer ; GII ; genomic Instability Index ; LS ; Lynch syndrome ; MACS ; microsatellite and chromosome stable tumors ; MMR ; mismatch repair ; MSI ; microsatellite instability ; MSS ; microsatellite stability ; OS ; overall survival

刊名：Neoplasia

出版年：2017

6.The race to target MET exon 14 skipping alterations in non-small cell lung cancer: The Why, the How, the Who, the Unknown, and the Inevitable

作者：Thanyanan Reungwetwattana^a ; Ying Liang^b ; Viola Zhu^c ; ^d ; Sai-Hong Ignatius Ou^d ; ^{ignatius.ou@uci.edu}

关键词：ALK ; anaplastic lymphoma kinase ; CNS ; central nervous system ; EGFR ; epidermal growth factor receptor ; FDA ; food and drug administration ; GCN ; gene copy number ; HGF ; hepatocyte growth factor ; IC50 ; half inhibitory concentration ; IHC ; immunohistochemistry ; mAb ; monoclonal antibody ; METex14 ; MET exon 14 ; METex14+ NSCLC ; METex14 altered NSCLC ; NSCLC ; non-small cell lung cancer ; ORR ; overall response rate ; PD-1 ; programmed cell death protein 1 ; RTK ; receptor tyrosine kinase ; SqCC ; squamous cell carci

刊名：Lung Cancer

出版年：2017

7.Mutant allele specific imbalance in oncogenes with copy number alterations: Occurrence, mechanisms, and potential clinical implications

作者：Chih-Chieh Yu^a ; Wanglong Qiu^a ; Caroline S. Juang^a ; Mahesh M. Mansukhani^b ; Balazs Halmos^c ; Gloria H. Su^a ; ^b ; ^d ; ^{gs2157@columbia.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：MASI ; UPD ; Loss of wild-type allele ; KRAS ; EGFR ; PDAC

刊名：Cancer Letters

出版年：2017

8.Comprehensive genomic sequencing and the molecular profiles of clinically advanced breast cancer

作者：Jeffrey S. Ross¹ ; ² ; ^{jross@foundationmedicine.com} ; Laurie M. Gay¹

关键词：Next-generation sequencing ; comprehensive genomic profiling ; breast carcinoma ; ERBB2 ; HER2 ; triple-negative breast cancer ; tumour mutational burden ; clinically relevant genomic alterations

刊名：Pathology

出版年：2017

9.Intratumoral and Intertumoral Genomic Heterogeneity of Multifocal Localized Prostate Cancer Impacts Molecular Classifications and Genomic Prognosticators

作者：Lei Wei^a ; ^&dagger ; ; Jianmin Wang^a ; ^&dagger ; ; Erika Lampert^b ; Simon Schlanger^b ; Adam D. DePriest^c ; Qiang Hu^a ; Eduardo Cortes Gomez^a ; Mitsuko Murakam^a ; Sean T. Glenn^c ; Jeffrey Conroy^d ; Carl Morrison^e ; Gissou Azabdaftari^e ; James L. Mohler^f ; Song Liu^a ; ^&Dagger ; ; Hannelore V. Heemers^b ; ^g ; ^h ; ^&Dagger ; ; ^{heemerh@ccf.org}

关键词：Prostatic adenocarcinoma ; Androgen deprivation therapy ; Castration ; Radiation therapy ; Somatic alterations ; Active surveillance ; Indolent ; Personalized medicine ; Actionable target

刊名：European Urology

出版年：2017

10.Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

作者：Mayuko Furuta¹ ; Masaki Ueno² ; Akihiro Fujimoto¹ ; Shinya Hayami² ; Satoru Yasukawa³ ; Fumiyoshi Kojima⁴ ; Koji Arihiro⁵ ; Yoshiiku Kawakami⁶ ; Christopher P. Wardell¹ ; Yuichi Shiraishi⁷ ; Hiroko Tanaka⁷ ; Kaoru Nakano¹ ; Kazuhiro Maejima¹ ; Aya Sasaki-Oku¹ ; Naoki Tokunaga¹ ; Keith A. Boroevich⁸ ; Tetsuo Abe⁸ ; Hiroshi Aikata⁶ ; Hideki Ohdan⁹ ; Kunihito Gotoh¹⁰ ; Michiaki Kubo¹¹ ; Tatsuhiko Tsunoda⁸ ; ¹² ; Satoru Miyano⁷ ; Kazuaki Chayama⁶ ; Hiroki Yamaue² ; ^{yamaue-h@wakayama-med.ac.jp} ; Hidewaki Nakagawa¹ ; ^{hidewaki@ims.u-tookoyo.ac.jp}

关键词：Liver cancer ; Somatic SNVs ; Multi-centric occurrence ; Intrahepatic metastasis ; Whole genome sequencing ; Hepatocellular Carcinoma

刊名：Journal of Hepatology

出版年：2017

按检索点细分(489)

题名(59)

关键词(21)

文摘(409)

按出版年细分(489)

2027年及以后(16)

2017年(11)

2016年(38)

2015年(11)

2013年(40)

2012年(43)

2011年(46)

2010年(47)

2009年(30)

2008年(30)

2007年(22)

2006年(29)

2005年(28)

2004年(21)

2003年(8)

2002年(17)

2001年(11)

2000年(7)

2000年及以前(34)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700