作者：Inmaculada Medina-Caliz¹ ; ^a ; ^&dagger ; ; Mercedes Robles-Diaz¹ ; ^a ; ^&dagger ; ; Beatriz Garcia-Muñ ; oz¹ ; Camilla Stephens¹ ; ^a ; Aida Ortega-Alonso¹ ; Miren Garcia-Cortes¹ ; ^a ; Andres Gonzá ; lez-Jimenez¹ ; Judith A. Sanabria-Cabrera¹ ; Inmaculada Moreno¹ ; ^a ; M. Carmen Fernandez² ; Manuel Romero-Gomez³ ; ^a ; Jose M. Navarro⁴ ; Ana Mª ; Barriocanal⁵ ; Eva Montane⁵ ; Hacibe Hallal⁶ ; Sonia Blanco⁷ ; German Soriano⁸ ; ^a ; Eva M. Roman⁸ ; ^a ; Elena Gó ; mez-Dominguez⁹ ; Agustin Castiella¹⁰ ; Eva M. Zapata¹⁰ ; Miguel Jimenez-Perez¹¹ ; Jose M. Moreno¹² ; Ana Aldea-Perona¹³ ; Manuel Herná ; ndez-Guerra¹⁴ ; Martin Prieto¹⁵ ; ^a ; Miguel E. Zoubek¹ ; Neil Kaplowitz¹⁶ ; M. Isabel Lucena¹ ; ^a ; ^{lucena@uma.es" class="auth_mail" title="E-mail the corresponding author} ; Raul J. Andrade¹ ; ^a ; on behalf of the Spanish DILI registry

关键词：DILI ; drug-induced liver injury ; ALP ; alkaline phosphatase ; TB ; total bilirubin ; ULN ; upper limit of normal ; AST ; aspartate aminotransferase ; ALT ; alanine aminotransferase ; INR ; international normalized ratio ; R ; ratio ; HC ; hepatocellular ; Chol ; cholestatic ; Mix ; mixed ; CIOMS ; Council for International Organizations of Medical Sciences ; RUCAM ; Roussel Uclaf causality assessment method ; NASH ; non-alcoholic steatohepatitis

刊名：Journal of Hepatology

出版年：2016

作者：Tomas Laho^a ; ^b ; John D. Clarke^a ; Anika L. Dzierlenga^a ; Hui Li^a ; David M. Klein^a ; Michael Goedken^c ; Stanislav Micuda^b ; Nathan J. Cherrington^a ; ^{cherrington@pharmacy.arizona.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ABC ; ATP-binding cassette family ; ABCC4 ; ATP-binding cassette family ; sub-family C ; gene 4 ; ADR ; adverse drug reaction ; ERK ; extracellular signal-regulated kinase ; GFR ; glomerular filtration rate ; MCD ; methionine and choline deficient diet ; NAFLD ; nonalcoholic fatty liver disease ; NASH ; nonalcoholic steatohepatitis

刊名：Biochemical Pharmacology

出版年：2016

作者：Mohammed Azeemuddin^a ; Mohamed Rafiq^a ; ^{dr.rafiq@himalayawellness.com" class="auth_mail" title="E-mail the corresponding author} ; Suryakanth Dattatraya Anturlikar^a ; Lakkavalli Mohan Sharath Kumar^b ; Pralhad Sadashiv Patki^a ; Uddagiri Venkanna Babu^b ; Ramakrishnan Shyam^c

关键词：antifibrotic ; high-fat diet ; insulin resistance ; Liv.52 ; nonalcoholic steatohepatitis

刊名：Journal of Traditional and Complementary Medicine

出版年：2016

作者：Heiko S. Schadt^a ; Armin Wolf^a ; Francois Pognan^a ; Salah-Dine Chibout^a ; Michael Merz^a ; Gerd A. Kullak-Ublick^b ; ^c ; ^{gerd.kullak@usz.ch" class="auth_mail" title="E-mail the corresponding author}

刊名：Clinics and Research in Hepatology and Gastroenterology

出版年：2016

作者：Enas A. Abd El-Haleim ; ^{enas.ahmed@pharma.cu.edu.eg" class="auth_mail" title="E-mail the corresponding author} ; Ashraf K. Bahgat ; Samira Saleh

关键词：PPAR ; NASH ; SOCS-3 ; SREBP-1c ; Leptin ; Adiponectin

刊名：European Journal of Pharmacology

出版年：2016

作者：Justin D. Schumacher ; ^{Justin.d.schumacher@rutgers.edu" class="auth_mail" title="E-mail the corresponding author} ; Grace L. Guo

关键词：ACADL ; acyl-CoA dehydrogenase long chain ; ATF4 ; activating transcription factor 4 ; CAD ; cationic amphiphilic drug ; CASH ; chemotherapy-associated steatohepatitis ; CPT-I ; carnitine palmitoyltransferase I ; ETF ; electron transfer flavoprotein ; FOLFIRI ; chemotherapy regimen containing 5-fluorouracil ; leucovorin ; and irinotecan ; FOLFIRINOX ; 5-fluorouracil ; leucovorin ; irinotecan ; and oxaliplatin ; FOLFOX ; 5-fluorouracil ; leucovorin ; and oxaliplatin ; GI ; gastrointestinal ; HADH尾 ; beta-3-hydroxyacyl-CoA d

刊名：Toxicology and Applied Pharmacology

出版年：2015

作者：Nishika Sahini ; Jü ; rgen Borlak ; ^{Borlak.Juergen@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ACACB ; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta ; ACAT1 ; acetyl-CoA acetyltransferase 1 ; ACLY ; ATP citrate lyase ; AMPK ; 5&prime ; AMP-activated protein kinase ; ASCL1 ; acyl-CoA synthetase long-chain family member 1 ; ACSL4 ; acyl CoA synthetases long chain family4 ; AGPAT9 ; acylglycerol-3-phosphate O-acyltransferase 9 ; ANGPTL4 ; angiopoietin-like 4 ; ANXA2 ; annexin A2 ; APOB ; apolipoprotein B ; AQP4 ; aquaporin 4 ; ARG2 ; arginase 2 ; BCL6 ; B-Cell CLL/lymphoma 6 ; β2AR ; β2 adregenic receptor ; CAV

刊名：Translational Research

出版年：2016

作者：Keisaku Sato¹ ; ² ; ^&dagger ; ; Fanyin Meng¹ ; ² ; ³ ; ⁴ ; ^&dagger ; ; Shannon Glaser¹ ; ² ; ³ ; Gianfranco Alpini¹ ; ² ; ³ ; ^{galpini@medicine.tamhsc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CCA ; cholangiocarcinoma ; DILI ; drug-induced liver injury ; EV ; extracellular vesicle ; MVBs ; multivesicular bodies ; HBV ; hepatitis B virus ; HCC ; hepatocellular carcinoma ; HCV ; hepatitis C virus ; IFN ; interferon ; LPS ; lipopolysaccharide ; miRNA ; microRNA ; MSC ; mesenchymal stem cell ; N-Heps ; normal human hepatocytes ; MVB ; multivesicular bodies ; NAFLD ; non-alcoholic fatty liver disease ; NASH ; non-alcoholic steatohepatitis ; PGDH ; 15-hydroxyprostaglandin dehydrogenase ; Pre-miRNA ; miRNA precursor ; Pri-mi

刊名：Journal of Hepatology

出版年：2016

作者：Deepak Amarapurkar^* ; ^{amarapurkar@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Anjali Amarapurkar^&dagger ;

关键词：AIH ; autoimmune hepatitis ; APRI ; aspartate transaminases to platelet ratio index ; CMV ; cytomegalovirus ; EBV ; Epstein bar virus ; HCC ; hepatocellular carcinoma ; HEV ; hepatitis E virus ; INCPH ; idiopathic noncirrhotic portal hypertension ; LB ; liver biopsy ; LD ; liver disease ; NAFLD ; nonalcoholic fatty liver disease ; NASH ; nonalcoholic steatohepatitis ; NRH ; nodular regenerative hyperplasia

刊名：Journal of Clinical and Experimental Hepatology

出版年：2015

作者：Manuela G. Neuman^a ; ^b ; ^{manuela.neuman@utoronto.ca" class="auth_mail" title="E-mail the corresponding author} ; Stephen Malnick^c ; Yaakov Maor^c ; Radu M. Nanau^a ; Ehud Melzer^c ; Peter Ferenci^d ; Helmut K. Seitz^e ; ^f ; Sebastian Mueller^e ; ^f ; Haim Mell^g ; Didier Samuel^h ; Lawrence B. Cohenⁱ ; Kusum K. Kharbanda^j ; Natalia A. Osna^j ; Murali Ganesan^j ; Kyle J. Thompson^k ; Iain H. McKillop^k ; Abraham Bautista^l ; Ramon Bataller^m ; ⁿ ; Samuel W. French^o

关键词：ALD ; alcoholic liver disease ; ASH ; alcoholic steatohepatitis ; AST ; aspartate aminotransferase ; ALT ; alanine aminotransferase ; BAL ; blood alcohol level ; CI ; confidence interval ; CYP2E1 ; cytochrome p450 2E1 ; DNA ; deoxyribonucleic acid ; HBV ; hepatitis B virus ; HCC ; hepatocellular carcinoma ; HCV ; hepatitis C virus ; HIV ; human immunodeficiency virus ; hsCRP ; high-sensitivity C-reactive protein ; IFN ; interferon ; IL ; interleukin ; LBP ; lipopolysaccharides-binding protein ; LPS ; lipopolysaccharide ; MCP ; mo

刊名：Experimental and Molecular Pathology

出版年：2015