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在“Elsevier电子期刊”中，命中：26条，耗时：小于0.01 秒

1.Novel 12N-substituted matrinanes as potential anti-coxsackievirus agents

作者：Ying&ndash ; Hong Li^a ; ¹ ; Sheng Tang^a ; ¹ ; Yu&ndash ; Huan Li^a ; Xin&ndash ; Yue Cheng^a ; Xin Zhang^a ; Yan&ndash ; Xiang Wang^a ; Feng Su^b ; ^{sufengvip@126.com} ; Dan&ndash ; Qing Song^a ; ^{songdanqingsdq@hotmail.com}

关键词：Matrinane ; Structure&ndash ; activity relationship ; Coxsakievirus ; Broad-spectrum ; Druglike

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Optimization and biological evaluation of celastrol derivatives as Hsp90-Cdc37 interaction disruptors with improved druglike properties

作者：Fen Jiang ; Hui-Jie Wang ; Qi-Chao Bao ; Lei Wang ; Yu-Hui Jin ; Qiong Zhang ; Di Jiang ; Qi-Dong You ; ^{youqidong@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Xiao-Li Xu ; ^{xuxiao_li@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Celastrol ; Hsp90&ndash ; Cdc37 interaction ; HTRF ; Structure&ndash ; activity relationship ; Druglike properties

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

3.Synthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitors

作者：Sheng-Biao Wang^a ; Mu-Tian Cui^a ; Xiao-Feng Wang^a ; ^d ; Emika Ohkoshi^b ; Masuo Goto^b ; De-Xuan Yang^c ; Linna Li^c ; Shoujun Yuan^c ; Susan L. Morris-Natschke^b ; Kuo-Hsiung Lee^b ; ^e ; ^{khlee@unc.edu" class="auth_mail" title="E-mail the corresponding author} ; Lan Xie^a ; ^b ; ^{lanxie4@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：PXQXFGCRWHTVBD-UHFFFAOYSA-N ; NRYHKDJEPGDAGX-UHFFFAOYSA-N ; IWPFYKIFKHNHAS-UHFFFAOYSA-N ; XMKZPZBUKQMHNF-UHFFFAOYSA-N ; AFNWKIKMTQIWHU-UHFFFAOYSA-N ; QGEAHLONJRLMKZ-UHFFFAOYSA-N ; ZEXOTOJJEIBRDN-UHFFFAOYSA-N ; HMMJKDJDJCYCBK-UHFFFAOYSA-N ; RMRSKURFSGCSFM-UHFFFAOYSA-N ; HKIFQJOVGYXXBB-UHFFFAOYSA-N ; RQKOQBFNLXPPSW-UHFFFAOYSA-N ; IJLDJEASLDJCDS-UHFFFAOYSA-N ; RANDQPGUBTWPSC-UHFFFAOYSA-N ; ZVIBISIIUYWHAM-UHFFFAOYSA-N ; HUZKIRAWCBJPAF-UHFFFAOYSA-N ; PEBCBFJYPZBCNX-UHFFFAOYSA-N ; QDFNTPGVPJPEHU-UHFFFAOYSA-N ; QXDLEVG

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Design of Druglike Small Molecules with LYN-Specific Binding

作者：D.S. Dalafave

刊名：Biophysical Journal

出版年：28 January, 2014

5.Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines as highly potent EGFR-TK inhibitors with Src-family activity

关键词：Pyrrolopyrimidine ; EGFR-TK ; Src-kinase ; Cancer ; CSF1R kinase ; Erlotinib

刊名：European Journal of Pharmaceutical Sciences

出版年：1 August 2014

6.AutoGrow 3.0: An improved algorithm for chemically tractable, semi-automated protein inhibitor design

作者：Jacob D. Durrant ; Steffen Lindert ; J. Andrew McCammon

关键词：Drug design ; Click chemistry ; Autogrow ; Computational chemistry

刊名：Journal of Molecular Graphics and Modelling

出版年：2013

7.Small Druglike Molecules with Specific Binding to Plk1 Or LYN Kinases

作者：D.S. Dalafave

刊名：Biophysical Journal

出版年：2013

8.Novel, druglike 1,7-disubstituted 2,3,4,5-tetrahydro-1H-benzo[b]azepine-based selective inhibitors of human neuronal nitric oxide synthase (nNOS)

作者：Subhash C. Annedi^a ; ^{sannedi@neuraxon.com} ; Jailall Ramnauth^a ; Michele Cossette^a ; Shawn P. Maddaford^a ; Peter Dove^a ; Suman Rakhit^a ; John S. Andrews^a ; Frank Porreca^b

关键词：234 ; 5-Tetrahydro-1H-benzo[b]azepine derivatives ; Nitric oxide ; Nitric oxide synthase ; Selective neuronal nitric oxide synthase inhibitors ; Neuropathic pain

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

9.Sweetened-Fat Intake Sensitizes Gamma-Aminobutyric Acid¡ªMediated Feeding Responses Elicited from the Nucleus Accumbens Shell

作者：Sarah Newman^a ; Lindsay Pascal^a ; ^b ; Ken Sadeghian^a ; Brian A. Baldo^a ; ^b ; ^{babaldo@wisc.edu}

关键词：DAMGO ; feeding behavior ; GABAA receptor ; musimol ; opioid ; sensitization

刊名：Biological Psychiatry

出版年：2013

10.A novel druglike spleen tyrosine kinase binder prevents anaphylactic shock when administered orally

作者：Elsa Mazuc ; Bruno O. Villoutreix ; Odile Malbec ; Thomas Roumier ; Sé ; bastien Fleury ; Jean-Paul Leonetti ; David Dombrowicz ; Marc Daë ; ron ; Pierre Martineau ; Piona Dariavach

关键词：Allergy and inflammation ; anaphylactic shock ; degranulation ; druglike compound ; mast cells/basophils ; tyrosine kinase ; Syk

刊名：Journal of Allergy and Clinical Immunology

出版年：2008

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