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在“Elsevier电子期刊”中，命中：1,263条，耗时：0.0959456 秒

在所有数据库中总计命中：14,559条

1.Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

作者：Natasha B. Leighl¹ ; Naiyer A. Rizvi² ; Lopes Gilberto de Lima Jr.³ ; ⁴ ; Wichit Arpornwirat⁵ ; Charles M. Rudin⁶ ; Alberto A. Chiappori⁷ ; Myung-Ju Ahn⁸ ; Laura Q.M. Chow⁹ ; Lyudmila Bazhenova¹⁰ ; Arunee Dechaphunkul¹¹ ; Patrapim Sunpaweravong¹² ; Keith Eaton¹³ ; ¹⁴ ; Jihong Chen¹⁵ ; Sonja Medley¹⁵ ; Srinivasu Poondru¹⁵ ; Margaret Singh¹⁵ ; Joyce Steinberg¹⁵ ; Rosalyn A. Juergens¹⁶ ; ^{juergensr@hhsc.ca} ; Shirish M. Gadgeel¹⁷ ; ¹⁸

关键词：Combination ; Epidermal growth factor receptor inhibitor ; First-line therapy ; Insulin-like growth factor-1 inhibitor ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

2.Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility

作者：Duncan Hieu M. Dam¹ ; ² ; Xiao-Qi Wang¹ ; ² ; Sarah Sheu¹ ; Mahima Vijay¹ ; Desmond Shipp¹ ; Luke Miller¹ ; Amy S. Paller¹ ; ^{apaller@northwestern.edu}

关键词：AS ; antisense oligonucleotide ; GCS ; glucosylceramide synthase ; GCSI ; glucosylceramide synthase inhibitor ; GM3S ; ganglioside GM3 synthase ; IGF-1 ; insulin-like growth factor-1 ; IGF1R ; insulin-like growth factor-1 receptor ; IR ; insulin receptor ; M2D3 ; GM2/GD2 and GD3 synthases ; NHEK ; normal human epidermal keratinocyte ; shRNA ; short hairpin RNA ; siRNA ; small interfering RNA ; SNA ; spherical nucleic acid

刊名：Journal of Investigative Dermatology

出版年：2017

3.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

4.Survival of Asian Females With Advanced Lung Cancer in the Era of Tyrosine Kinase Inhibitor Therapy

作者：Daniel J. Becker¹ ; ² ; ^{daniel.becker@nyumc.org} ; Juan P. Wisnivesky³ ; Michael L. Grossbard² ; Abraham Chachoua² ; D. Ross Camidge⁴ ; Benjamin P. Levy³

关键词：Epidermal growth factor receptor ; Ethnic disparities ; Outcome research ; SEER ; TKIs

刊名：Clinical Lung Cancer

出版年：2017

5.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

6.An autopsy case of bronchiolitis obliterans as a previously unrecognized adverse event of afatinib treatment

关键词：BO ; bronchiolitis obliterans ; TKI ; tyrosine kinase inhibitor ; EGFR ; epidermal growth factor receptor ; NSCLC ; non-small cell lung cancer ; ILD ; interstitial lung disease ; FEV1 ; forced expiratory volume in 1s

刊名：Respiratory Investigation

出版年：2017

7.Systematic Identification of Oncogenic EGFR Interaction Partners

作者：Julia Petschnigg¹ ; Max Kotlyar² ; Louise Blair¹ ; Igor Jurisica² ; ³ ; ⁴ ; ⁵ ; Igor Stagljar⁶ ; ⁷ ; ⁸ ; Robin Ketteler¹ ; ^{r.ketteler@ucl.ac.uk}

关键词：EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-regulated kinase ; GFP ; green fluorescent protein ; Grb2 ; growth factor receptor-bound protein 2 ; SH ; Src homology ; MAPK ; mitogen-activated protein kinase ; TK ; tyrosine kinase ; TKI ; TK inhibitor ; NSCLC ; non-small cell lung cancer ; MaMTH ; mammalian membrane two-hybrid ; TACC ; transforming acidic coiled-coil protein ; GO ; gene ontology ; Cub ; C-terminal half of ubiquitin ; TF ; transcription factor ; Nub ; N-ter

刊名：Journal of Molecular Biology

出版年：2017

8.The Na⁺-D-glucose cotransporters SGLT1 and SGLT2 are targets for the treatment of diabetes and cancer

作者：Hermann Koepsell ^{Hermann@koepsell.de}

关键词：AMG ; α-methyl-D-glucopyranoside ; BBB ; blood brain barrier ; BBM ; brush-border membrane ; BLM ; basolateral membrane ; CREB ; cAMP response element binding protein ; DNJ ; 1-deoxynojirimycin ; EKA ; euglycemic ketoacidosis ; GGM ; glucose-galactose malabsorption ; GIP ; glucose-dependent insulinotropic peptide ; GLP-1 ; glucagon like peptide 1 ; GLP-2 ; glucagon like peptide 2 ; EGF ; epidermal growth factor ; EGFR ; EGF receptor ; GIP ; glucose-dependent insulinotropic hormone ; GMI ; genital mycotic infection ; GFR ; glo

刊名：Pharmacology & Therapeutics

出版年：2017

9.Tyrosine kinase/phosphatase inhibitors decrease dengue virus production in HepG2 cells

作者：Thawornchai Limjindaporn^a ; ^{thawornchai.lim@mahidol.ac.th} ; Jutatip Panaampon^a ; Shilu Malakar^b ; Sansanee Noisakran^c ; Pa-thai Yenchitsomanus^d

关键词：Epidermal growth factor receptor inhibitor ; Protein tyrosine phosphatase inhibitor ; Antiviral activity ; Dengue virus ; HepG2 cells

刊名：Biochemical and Biophysical Research Communications

出版年：2017

10.Evolution and Increasing Complexity of the Therapeutic Landscape in Advanced Non-Small-cell Lung Cancer

作者：David R. Gandara ; ^{drgandara@ucdavis.edu} ; Jonathan W. Riess ; Karen Kelly ; Tianhong Li ; Philip C. Mack ; Primo N. Lara Jr.

关键词：Epidermal growth factor receptor ; NSCLC ; Targeted therapy ; Therapeutic landscape ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

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