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在“Elsevier电子期刊”中，命中：2,258条，耗时：0.0649679 秒

在所有数据库中总计命中：13,331条

1.Molecular dynamics simulation of the human estrogen receptor alpha: contribution to the pharmacophore of the agonists

作者：Dessislava Jereva^a ; ^{dessislava.jereva@biomed.bas.bg} ; Filip Fratev^a ; ^b ; ^{fratev@biomed.bas.bg} ; Ivanka Tsakovska^a ; ^{itsakovska@biomed.bas.bg} ; Petko Alov^a ; ^{petko.alov@biophys.bas.bg} ; Tania Pencheva^a ; ^{tania.pencheva@biomed.bas.bg} ; Ilza Pajeva^a ; ^{pajeva@biomed.bas.bg}

关键词：Human estrogen receptor alpha ; Agonist ; Pharmacophore ; Molecular dynamics simulation

刊名：Mathematics and Computers in Simulation

出版年：2017

2.BODIPY-17α-ethynylestradiol conjugates: Synthesis, fluorescence properties and receptor binding affinities

作者：Samira Osati^a ; Hasrat Ali^a ; Fernanda Marques^b ; Michel Paquette^a ; Simon Beaudoin^a ; Brigitte Guerin^a ; ^c ; Jeffrey V. Leyton^a ; ^c ; Johan E. van Lier^a ; ^c ; ^{Johan.E.vanlier@usherbrooke.ca}

关键词：BODIPY ; 17α-Ethynylestradiol conjugates ; Estrogen receptor ; RBA ; Fluorescence imaging

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.Sensitive detection of estradiol based on ligand binding domain of estrogen receptor and gold nanoparticles

作者：Pimchanok Busayapongchai^a ; Sineenat Siri^b ; ^{ssinee@sut.ac.th}

关键词：Colorimetric detection ; Co-activator ; Estradiol ; Estrogen receptor ; Gold nanoparticles

刊名：Analytical Biochemistry

出版年：2017

4.Estradiol prodrugs (EP) for efficient oral estrogen treatment and abolished effects on estrogen modulated liver functions

作者：W. Elger^a ; R. Wyrwa^d ; G. Ahmed^a ; F. Meece^a ; H.B. Nair^a ; B. Santhamma^a ; Z. Killeen^e ; B. Schneider^a ; R. Meister^c ; H. Schubert^b ; K. Nickisch^a ; ^{knickisch@evestra.com} ; ^{klausnickisch@aol.com}

关键词：AUC ; area under the curve ; BW ; body weight ; C0 ; extrapolated concentration time zero (i. v.) ; Cmax ; maximum concentration ; CA-II ; carbonic anhydrase II ; CBG ; cortisol binding globulin ; COC ; combined oral contraceptive ; EDTA ; ethylene diamine tetra acetic acid ; EE ; ethinyl estradiol ; EMATE ; estrone sulfamate ; EP ; estradiol prodrug ; ER ; estrogen receptor ; ERT ; estrogen replacement therapy ; ES ; estradiol sulfamate ; E2 ; estradiol ; FSH ; follicle stimulating hormone ; GH-/IGF1 ; growth hormone / insulin

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

5.ERα inhibited myocardin-induced differentiation in uterine fibroids

作者：Xing-Hua Liao^a ; ^b ; ¹ ; ^{xinghualiao@hotmail.com} ; Jun-Yan Li^d ; ¹ ; Xiu-Mei Dong^a ; ^f ; Xiuhong Wang^e ; Yuan Xiang^a ; Hui Li^a ; Cheng-Xi Yu^a ; Jia-Peng Li^a ; Bai-Yin Yuan^a ; Jun Zhou^a ; ^c ; ^{zhoujun@wust.edu.cn} ; Tong-Cun Zhang^a ; ^b ; ^{zhangtongcun@wust.edu.cn}

关键词：USMC ; uterine smooth muscle cells ; α-SMA ; alpha smooth muscle actin ; PBS ; phosphate-buffered saline ; H&E ; hematoxylin and eosin ; DAPI ; 4&prime ; 6&prime ; -diamidino-2-phenylindole ; RT-PCR ; reverse-transcription polymerase chain reaction ; qRT-PCR ; quantitative real-time RT-PCR ; ChIP ; chromatin immunoprecipitation ; SERMs ; selective estrogen receptor modulators ; ERE ; estrogen receptor binding element ; ER ; estrogen receptors

刊名：Experimental Cell Research

出版年：2017

6.Metals and metastasis: Exploiting the role of metals in cancer metastasis to develop novel anti-metastatic agents

作者：Leyla Fouani¹ ; Sharleen V. Menezes¹ ; Mellow Paulson ; Des R. Richardson ; Zaklina Kovacevic ; ^{zaklina.kovacevic@sydney.edu.au}

关键词：CCBE1 ; collagen and calcium-binding EGF domains 1 ; CO ; carbon monoxide ; CSC ; cancer stem cell ; CTCs ; circulating tumor cells ; DpC ; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone ; DpT ; di-2-pyridylketone thiosemicarbazone ; Dp44mT ; 2-pyridylketone 4 ; 4-dimethyl-3-thiosemicarbazone ; ECM ; extracellular matrix ; eIF3a ; eukaryotic initiation factor 3a ; EMT ; epithelial to mesenchymal transition ; EPC ; epithelial progenitor cells ; ER ; estrogen receptor ; FAK ; focal adhesion kinase ; HIF-1α ; hyp

刊名：Pharmacological Research

出版年：2017

7.Estrogen receptors modulate striatal metabotropic receptor type 5 in intact and MPTP male mice model of Parkinson’s disease

作者：S. Al-Sweidi^a ; ^b ; M. Morissette^a ; T. Di Paolo^a ; ^b ; ^{therese.dipaolo@crchul.ulaval.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：A ; adenosine ; DA ; dopamine ; CNS ; central nervous system ; CREB ; cAMP response element-binding protein ; DAT ; dopamine transporter ; ERK ; extracellular signal-regulated kinase ; ER ; estrogen receptor ; ERKO ; estrogen receptor knock out ; L-DOPA ; levodopa ; MAPK ; mitogen-activated protein kinase ; mGlu ; metabotropic glutamate ; MPEP ; [2-methyl-6-(phenylethynyl)pyridine ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MTEP ; 3-[(2-methyl-1 ; 3-thiazol-4-yl)ethynyl] pyridine ; PD ; Parkinson&rsquo ; s disease

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2016

8.Simulations reveal increased fluctuations in estrogen receptor-alpha conformation upon antagonist binding

作者：Ho Leung Ng ^{hng@hawaii.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Estrogen receptor ; Hormone receptor ; Molecular dynamics ; Drug binding

刊名：Journal of Molecular Graphics and Modelling

出版年：2016

9.Recent progress in the development of protein-protein interaction inhibitors targeting androgen receptor-coactivator binding in prostate cancer

作者：Eric Biron^a ; ^b ; ^{eric.biron@pha.ulaval.ca" class="auth_mail" title="E-mail the corresponding author} ; Franç ; ois Bé ; dard^a ; ^b

关键词：AB ; Sandrogen-binding site ; AF ; activation function ; AR ; androgen receptor ; ARA ; androgen receptor-associated protein ; ARE ; androgen-responsive elements ; BF3 ; binding function 3 ; CBI ; coactivator binding inhibitor ; CBP ; CREB-binding protein ; CPRC ; castration-resistant prostate cancer ; CYP ; cytochrome P450 ; DBD ; DNA-binding domain ; DHT ; 5α-dihydrotestosterone ; ER ; estrogen receptor ; FP ; fluorescence polarization ; GRIP1 ; glutamate receptor interacting protein 1 ; LBD ; ligand-binding domain ; NLS ; n

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2016

10.A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β

作者：Li-Ming Zhao^a ; ^b ; Hai-Shan Jin^a ; ^b ; Jinzhong Liu^c ; Todd C. Skaar^c ; Joseph Ipe^c ; Wei Lv^a ; David A. Flockhart^c ; Mark Cushman^a ; ^{cushman@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AIs ; aromatase inhibitors ; ATAC ; arimidex ; tamoxifen ; alone or in combination ; DMSO ; dimethyl sulfoxide ; ER ; estrogen receptor ; EtOAc ; ethyl acetate ; EtOH ; ethanol ; MeOH ; methanol ; SAR ; structure&ndash ; activity relationship ; SERM ; selective estrogen receptor modulator ; THF ; tetrahydrofuran

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

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