搜索页_ Extracellular signal-regulated kinase (ERK)

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在“Elsevier电子期刊”中，命中：6,250条，耗时：0.0489751 秒

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1.Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-opioid receptor agonist is related to resistance to rewarding effects in a mouse model of bone cancer

作者：Atsushi Nakamura ; ^{atsushi_nakamura@shionogi.co.jp} ; Hiroko Ono ; Azusa Ando ; Mikie Hinata ; Kazuki Niidome ; Shigeki Omachi ; Gaku Sakaguchi ; Shunji Shinohara

关键词：Antinociception ; Bone cancer pain ; Extracellular regulated kinase ; Opioid ; Rewarding effect

刊名：Journal of Pharmacological Sciences

出版年：2017

2.5-HT₇ receptor-mediated fear conditioning and possible involvement of extracellular signal-regulated kinase

作者：Kotaro Takeda ; Minoru Tsuji ; ^{mtsuji@iuhw.ac.jp} ; Kazuya Miyagawa ; Hiroshi Takeda

关键词：5-HT ; serotonin ; DR4004 ; 2a-[4-(4-phenyl-123 ; 6-tetrahydropyridyl)butyl]-2a34 ; -tetrahydrobenzo(c ; d)indol-2-(1H)-one ; ERK ; extracellular signal-regulated kinase 1/2 ; pERK ; phosphorylated ERK ; CS ; conditioned stimulus ; US ; unconditioned stimulus ; mRNA ; messenger RNA ; i.p. ; intraperitoneally ; ANOVA ; analysis of variance ; TrkB ; tropomyosin-related kinase B ; BDNF ; brain-derived neurotrophic factor

刊名：Neuroscience Letters

出版年：2017

3.Cigarette smoke extract induces epithelial-mesenchymal transition of human bladder cancer T24 cells through activation of ERK1/2 pathway

作者：Xin Sun^a ; ¹ ; Qifei Deng^b ; ¹ ; Zhaofeng Liang^c ; Zhiqi Liu^a ; Hao Geng^a ; Li Zhao^a ; Qirui Zhou^d ; Jie Liu^a ; Jiaxing Ma^a ; Daming Wang^a ; Dexin Yu^a ; ^{yudx_urology@126.com} ; Caiyun Zhong^e ; ^{cyzhong@njmu.edu.cn}

关键词：CSE ; Cigarette smoke extract ; CS ; Cigarette smoke ; EMT ; Epithelial&ndash ; mesenchymal transition ; MAPK ; Mitogen-activated protein kinase ; ERK1/2 ; extracellular regulated protein kinases 1 and 2 ; AP-1 ; activator protein 1 ; DMSO ; dimethyl sulfoxide ; MTT ; thiazolyl blue tetrazolium bromide ; qRT-PCR ; quantitative reverse transcription-polymerase chain reaction

刊名：Biomedicine & Pharmacotherapy

出版年：2017

4.Perilla frutescens leaves extract ameliorates ultraviolet radiation-induced extracellular matrix damage in human dermal fibroblasts and hairless mice skin

作者：Jung-Soo Bae^a ; ^b ; ^c ; ¹ ; Mira Han^a ; ^b ; ^c ; ¹ ; Hee Soon Shin^d ; Min-Kyoung Kim^a ; ^b ; ^c ; Chang-Yup Shin^a ; ^b ; ^c ; Dong Hun Lee^a ; ^b ; ^c ; ^{ivymed27@snu.ac.kr} ; Jin Ho Chung^a ; ^b ; ^c ; ^e ; ^{jhchung@snu.ac.kr}

关键词：AP-1 ; activator protein-1 ; ECM ; extracellular matrix ; EMSA ; electrophoretic mobility shift assays ; ERK ; extracellular signal-regulated kinase ; HDF ; human dermal fibroblast ; JNK ; c-Jun N-terminal kinase ; MED ; minimal erythema dose ; MMP ; matrix metalloproteinases ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)&minus2 ; 5-diphenyltetrazolium bromide ; PBS ; phosphate-buffered saline ; PLE ; Perilla frutescens leaves extract ; ROS ; reactive oxygen species ; SDS-PAGE ; sodium dodecyl sulfate-polyacrylamide gel electropho

刊名：Journal of Ethnopharmacology

出版年：2017

5.Agastache rugosa Kuntze extract, containing the active component rosmarinic acid, prevents atherosclerosis through up-regulation of the cyclin-dependent kinase inhibitors p21^WAF1/CIP1 and p27^KIP1

作者：Jung-Jin Lee^a ; ^{mhjj3998@kiom.re.kr} ; Ji-Hye Lee^a ; ^{ideal0723@kiom.re.kr} ; Min Jung Gu^a ; ^{guminjung@kiom.re.kr} ; Joo-Hui Han^b ; ^{han5621@cnu.ac.kr} ; Won-Kyung Cho^a ; ^{wkcho@kiom.re.kr} ; Jin Yeul Ma^a ; ^{jyma@kiom.re.kr}

关键词：AKT ; phosphatidylinositol 3-kinase-linked protein kinase ; A.rugose ; Agastacherugosa Kuntze ; BrdU ; bromodeoxyuridine ; CA ; caffeic acid ; CCK-8 ; cell counting Kit-8 ; CDK ; cyclin-dependent kinase ; CKI ; cyclin-dependent kinase inhibitor ; DAD ; diode array UV/VIS detector ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; ERK ; extracellular signal regulated kinase 1/2 ; FBS ; fetal bovine serum ; HPLC ; high-performance liquid chromatographic ; JNK ; c-Jun N-terminal kinase ; PBS ; phosphate-buffered salin

刊名：Journal of Functional Foods

出版年：2017

6.Expression and activation of platelet-derived growth factor β receptor, mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) and extracellular signal-regulated kinase (ERK) in canine mammary tumours

作者：Gennaro Altamura^a ; ^{gennaro.altamura@unina.it} ; Barbara degli Uberti^b ; ^{barbara.degliuberti@cert.izsmportici.it} ; Giorgio Galiero^b ; ^{giorgio.galiero@cert.izsmportici.it} ; Manuela Martano^a ; ^{manuela.martano@unina.it} ; Antonella Pirro^a ; ^{divas3@hotmal.it} ; Marco Russo^a ; ^{marco.russo@unina.it} ; Giuseppe Borzacchiello^a ; ^{borzacch@unina.it}

关键词：PDGFβR ; MEK ; ERK ; TKR inhibitors ; Oncology

刊名：Research in Veterinary Science

出版年：2017

7.Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation

作者：Wei Wu^a ; ^b ; Mahendra D. Chordia^c ; ^g ; Barry P. Hart^d ; E. Sathyajith Kumarasinghe^c ; Min K. Ji^c ; Ajay Bhargava^e ; Michael W. Lawlor^f ; Ji-Yeon Shin^a ; ^b ; Fusako Sera^a ; Shunichi Homma^a ; Antoine Muchir^a ; ^b ; ^h ; Uday R. Khire^c ; ^d ; ^{ukhire@allomek.com} ; Howard J. Worman^a ; ^b ; ^{hjw14@columbia.edu}

关键词：Cardiomyopathy ; Emery-Dreifuss muscular dystrophy ; Extracellular signal-regulated kinase ; Lamin ; MEK inhibitor ; Mitogen-activated protein kinase

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

8.Contrary influence of clinically applied sorafenib concentrations among hepatocellular carcinoma patients

作者：Zu-Yau Lin^a ; ^b ; ^{linzuyau@yahoo.com.tw} ; Wan-Long Chuang^a ; ^b

关键词：HCC ; hepatocellular carcinoma ; MAPK ; mitogen-activated protein kinase ; ERK ; extracellular signal regulated kinase ; MEK ; MAPK (ERK) kinase ; RT-PCR ; reverse transcriptase-polymerase chain reaction

刊名：Biomedicine & Pharmacotherapy

出版年：2017

9.Chemerin-induced arterial contraction is G_i- and calcium-dependent

作者：David J. Ferland ; ^{ferlandd@msu.edu} ; Emma S. Darios ; Richard R. Neubig ; Benita Sjö ; gren ; Nguyen Truong ; Rosa Torres ; Thomas S. Dexheimer ; Janice M. Thompson ; Stephanie W. Watts

关键词：Akt ; protein kinase B ; ANG II ; angiotensin II ; CaM ; calmodulin ; CCRL2 ; chemokine (CC motif) receptor-like 2 ; CMKLR1 ; chemokine-like receptor 1 ; Erk MAPK ; extracellular signal-regulated kinase mitogen activated protein kinase ; GAP ; GTPase activating protein ; GEF ; guanine nucleotide exchange factor ; GPR1 ; G protein-coupled receptor 1 ; MLC ; myosin light-chain ; MLCK ; myosin light-chain kinase ; MLCP ; myosin light-chain phosphatase ; PD098059 ; 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one ; PE ; phenyleph

刊名：Vascular Pharmacology

出版年：2017

10.Potentiation and tolerance of toll-like receptor priming in human endothelial cells

作者：Stephen R. Koch^a ; Fred S. Lamb^a ; Judith Hellman^b ; Edward R. Sherwood^c ; Ryan J. Stark^a ; ^{ryan.stark@vanderbilt.edu}

关键词：ELISA ; enzyme-linked immunosorbent assay ; ERK ; extracellular signal-regulated kinase ; HMVEC ; human dermal microvascular endothelial cell ; HUVEC ; human umbilical vein endothelial cell ; IL-6 ; interleukin 6 ; IKK ; IκB kinase ; IP-10 ; interferon gamma-induced protein 10 ; IRF ; interferon regulatory factor ; JNK ; c-Jun amino-terminal kinase ; LPS ; lipopolysaccharide ; LTA ; lipoteichoic acid ; MAPK ; mitogen-activated protein kinase ; MyD88 ; myeloid differentiation primary response gene 88 ; Nec-1s ; 7-Cl-O-Nec1

刊名：Translational Research

出版年：2017

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