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在“Elsevier电子期刊”中，命中：16条，耗时：小于0.01 秒

在所有数据库中总计命中：28条

1.545 - Identifying high quality, potent and selective inhibitors of ATM kinase: Discovery of AZD0156

作者：B. Barlaam ; K. Pike

刊名：European Journal of Cancer

出版年：2016

2.Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers

作者：Bernard Barlaam^b ; ^{bernard.barlaam2@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Sabina Cosulich^b ; Bé ; né ; dicte Delouvrié ; ^a ; Rebecca Ellston^b ; Martina Fitzek^b ; Hervé ; Germain^a ; Stephen Green^b ; Urs Hancox^b ; Craig S. Harris^a ; ^&dagger ; ; Kevin Hudson^b ; Christine Lambert-van der Brempt^a ; Honorine Lebraud^a ; Franç ; oise Magnien^a ; Maryannick Lamorlette^a ; Antoine Le Griffon^a ; Ré ; my Morgentin^a ; ^&Dagger ; ; Gilles Ouvry^a ; ^&dagger ; ; Ken Page^b ; Georges Pasquet^a ; Urszula Polanska^b ; Linette Ruston^b ; Twana Saleh^a ; Michel Vautier^a ; Lara Ward^b

关键词：PI3Kα ; PI3Kδ ; Kinase ; PIK3CA mutation

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

3.Applying early discovery safety science to eliminate chemical toxicity and improve the pre-clinical efficacy of focal adhesion kinase inhibitors

作者：M. Anderton¹ ; ; S. Ashton² ; B. Barlaam³ ; C. Jones² ; C. Jones²

刊名：Toxicology Letters

出版年：2015

4.Body schema building during childhood and adolescence: A neurosensory approach

作者：C. Assaiante ; F. Barlaam ; F. Cignetti ; M. Vaugoyeau

关键词：Body schema ; Internal representations ; Anticipation ; Multisensory integration ; Childhood and adolescence

刊名：Neurophysiologie Clinique / Clinical Neurophysiology

出版年：January, 2014

5.Rythme mu et pr茅cision temporelle de l鈥檌nhibition musculaire聽: une longue maturation au cours de l鈥檃dolescence

作者：F. Barlaam ; C. Fortin ; M. Vaugoyeau ; C. Schmitz ; C. Assaiante

关键词：Ajustements posturaux anticipés ; Adolescence ; É ; lectromyographie ; É ; lectroencé ; phalographie ; Rythme mu

刊名：Neurophysiologie Clinique / Clinical Neurophysiology

出版年：January, 2014

6.Preparation of 6-aminoquinazolin-4(3H)-ones via direct S_NAr on the quinazoline ring

作者：Bernard Barlaam ; Craig S. Harris ; ; ; ^{craig.harris2@astrazeneca.com} ; Jonathan Lecoq ; Ha Thi Hoang Nguyen

关键词：Direct S_NAr ; Unactivated fluorides ; Quinazolin-4-(3H)-one

刊名：Tetrahedron

出版年：2012

7.Development of action representation during adolescence as assessed from anticipatory control in a bimanual load-lifting task

作者：F. Barlaam ; C. Fortin ; M. Vaugoyeau ; C. Schmitz ; C. Assaiante

关键词：APAs ; anticipatory postural adjustments ; EMG ; electromyographic ; MA ; maximum angular amplitude ; MA % ; maximum angular amplitude expressed in percentages of imposed situation ; T0 ; onset of unloading

刊名：Neuroscience

出版年：2012

8.Inhibitors of the tyrosine kinase EphB4. Part 3: Identification of non-benzodioxole-based kinase inhibitors

作者：Catherine Bardelle ; Bernard Barlaam ; Nigel Brooks ; Tanya Coleman ; Darren Cross ; Richard Ducray ; Isabelle Green ; Christine Lambert-van der Brempt ; Annie Olivier ; Jon Read

关键词：EphB4 kinase inhibitor ; bis-Anilinopyrimidine

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2010

9.Novel 3-alkoxy-1H-pyrazolo[3,4-d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors

作者：Richard Ducray ; Peter Ballard ; Bernard C. Barlaam ; Mark D. Hickinson ; Jason G. Kettle ; Donald J. Ogilvie ; Catherine B. Trigwell

关键词：Pyrazolopyrimidines ; erbB2 ; Receptor tyrosine kinase

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2008

10.A new series of neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase

作者：Bernard Barlaam ; Peter Ballard ; Robert H. Bradbury ; Richard Ducray ; Hervé ; Germain ; D. Mark Hickinson ; Kevin Hudson ; Jason G. Kettle ; Teresa Klinowska ; Franç ; oise Magnien ; Donald J. Ogilvie ; A

关键词：Anilinoquinazoline ; C-5 substitution ; erbB2 kinase inhibitor

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2008

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